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Phase

Phase 2 8Phase 1 5Phase EARLY_PHASE1 1Phase 3 1Phase 1/2 1

Status

Completed 4Withdrawn 1

Sponsor Class

INDUSTRY 5OTHER 4NIH 4

Study Type

Interventional 5

Sponsor

Cancer Type

Tumor-Agnostic 3CNS 1Breast 1

Conditions

Neoplasms 3Glioma 1Glioblastoma 1Breast Neoplasms 1

Interventions

pembrolizumab 304Paclitaxel 206Carboplatin 200Gemcitabine 173Cisplatin 139Docetaxel 138Cyclophosphamide 136Nivolumab 129Bevacizumab 118Injections 111fludarabine 96atezolizumab 91Pemetrexed 90Dexamethasone 90Cetuximab 90Fluorouracil 84Irinotecan 77Rituximab 72Capecitabine 72venetoclax 71Azacitidine 70130-nm albumin-bound paclitaxel 67Leucovorin 65Fulvestrant 58Oxaliplatin 57durvalumab 56Trastuzumab 56Lenalidomide 55Ipilimumab 55Midazolam 54

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × INDUSTRY × reolysin × Clear all
NCT05519059 2023-11-22

Pelareorep and Paclitaxel Injection in Chinese Patients With Advanced or Metastatic Breast Cancer

Adlai Nortye Biopharma Co., Ltd.

Phase 1 Completed
15 enrolled
Breast

Breast Neoplasms

NCT01274624 2018-12-19

Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer

Oncolytics Biotech

Phase 1 Completed
36 enrolled
Tumor-Agnostic

Neoplasms

NCT02620423 2018-09-13

Study of Pembrolizumab With REOLYSIN® and Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma

Oncolytics Biotech

Phase 1 Completed
11 enrolled
Tumor-Agnostic

Neoplasms

NCT02723838 2017-03-07

Study of Intratumoral REOLYSIN® in Combination With Gemcitabine and Cisplatin as Neoadjuvant Therapy in Muscle-invasive Transitional Cell Carcinoma of the Bladder

Oncolytics Biotech

Phase 1 Withdrawn
Tumor-Agnostic

Neoplasms

NCT00528684 2014-10-02

Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas

Oncolytics Biotech

Phase 1 Completed
18 enrolled
CNS

Glioblastoma, Glioma

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