Clinical Trials Browser

Phase 2 × Interventional × reolysin × Clear all

NCT07446322 2026-05-05

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

Phase 2 Recruiting

60 enrolled

Gastrointestinal

Ras-mutated Metastatic Colorectal Cancer

NCT04445844 2025-04-04

INCMGA00012 and Pelareorep for the Treatment of Metastatic Triple Negative Breast Cancer, IRENE Study

Phase 2 Active not recruiting

25 enrolled

Breast

Triple Negative Breast Neoplasms

NCT04215146 2025-01-16

A Study to Assess Overall Response Rate by Inducing an Inflammatory Phenotype in Metastatic BReast cAnCEr With the Oncolytic Reovirus PeLareorEp in CombinaTion With Anti-PD-L1 Avelumab and Paclitaxel - BRACELET-1 Study

Phase 2 Active not recruiting

48 enrolled 13 charts

Breast

Breast Neoplasms

NCT01622543 2023-08-23

Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Cancer

Phase 2 Completed

109 enrolled 13 charts

Gastrointestinal

Colorectal Neoplasms

NCT01619813 2023-08-04

Reolysin Combined With Docetaxel and Prednisone or Docetaxel and Prednisone Alone in Metastatic Castration Resistant Prostate Cancer

Phase 2 Completed

85 enrolled

Genitourinary

Prostatic Neoplasms

NCT01656538 2023-08-04

A Study of Reolysin For Patients With Advanced/Metastatic Breast Cancer

Phase 2 Completed

81 enrolled

Breast

Breast Neoplasms

NCT01708993 2023-08-04

Reolysin in Previously Treated Advanced/Metastatic, Non Small Cell Lung Cancer Receiving Standard Salvage Therapy

Phase 2 Completed

166 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03723915 2022-10-05

Pembrolizumab and Pelareorep in Treating Patients With Advanced Pancreatic Cancer

Phase 2 Terminated

17 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT01199263 2020-09-16

Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Completed

108 enrolled 12 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01280058 2018-03-09

Carboplatin and Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Metastatic Pancreatic Cancer

Phase 2 Completed

73 enrolled 11 charts

Gastrointestinal

Pancreatic Neoplasms

NCT00998192 2016-03-31

A Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Squamous Cell Carcinoma of the Lung

Phase 2 Completed

32 enrolled

Tumor-Agnostic

Carcinoma, Neoplasm Metastasis

NCT00861627 2015-12-02

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin for Non-Small Cell Lung Cancer With KRAS or EGFR Activation

Phase 2 Completed

37 enrolled

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT00984464 2015-04-10

Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma

Phase 2 Completed

14 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT00998322 2015-04-10

A Study of REOLYSIN® in Combination With Gemcitabine in Patients With Advanced Pancreatic Adenocarcinoma

Phase 2 Completed

34 enrolled

Tumor-Agnostic

Adenocarcinoma, Neoplasm Metastasis

NCT00753038 2014-11-04

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Head and Neck Carcinoma

Phase 2 Completed

14 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma

NCT00503295 2014-10-02

Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung

Phase 2 Completed

53 enrolled

Sarcoma

Fibrosarcoma, Leiomyosarcoma, Sarcoma, Osteosarcoma, Sarcoma, Synovial, Histiocytoma, Malignant Fibrous

NCT00651157 2014-04-22

Viral Therapy in Treating Patients With Metastatic Melanoma

Phase 2 Completed

23 enrolled 6 charts

Dermatologic

Melanoma