Announcements Trials
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Phase

Phase 1 3Phase 2 2Phase 1/2 2

Status

Completed 3Withdrawn 2Terminated 2

Sponsor Class

INDUSTRY 5OTHER 2

Study Type

Interventional 7

Sponsor

Cancer Type

Thoracic 3Tumor-Agnostic 2Other solid neoplasm 1

Conditions

Small Cell Lung Carcinoma 2Neoplasms 2Solid Tumor 1Medical Oncology 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Cyclophosphamide 3162Cisplatin 3160Carboplatin 2938Paclitaxel 2673Radiotherapy 2648Gemcitabine 2547pembrolizumab 2331Docetaxel 2157Bevacizumab 2128Fluorouracil 1822Capecitabine 1784Oxaliplatin 1713Dexamethasone 1590Nivolumab 1517Doxorubicin 1477Rituximab 1454Etoposide 1342Magnetic Resonance Spectroscopy 1266Irinotecan 1235Leucovorin 1216Cytarabine 1123Pemetrexed 1062Drug Therapy 1062fludarabine 1050Vincristine 956Specimen Handling 936Prednisone 926Cetuximab 921Lenalidomide 916Trastuzumab 902

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Interventional × roniciclib × Clear all
NCT01573338 2021-04-08

Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 When Given Together With Chemotherapy and the Effectiveness of This Combination Treatment in Shrinking a Specific Type of Lung Tumors (Small Cell Lung Cancer)

Bayer

Phase 1/2 Terminated
43 enrolled
Thoracic

Small Cell Lung Carcinoma

NCT02161419 2018-06-25

CONCEPT-SCLC

Bayer

Phase 2 Terminated
142 enrolled
Thoracic

Small Cell Lung Carcinoma

NCT01188252 2017-01-09

Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 Given in a 3 Days on / 4 Days Off Schedule in Subjects With Advanced Malignancies

Bayer

Phase 1 Completed
112 enrolled
Tumor-Agnostic

Neoplasms

NCT02522910 2016-08-10

An Open-label Phase Ib/II Study of BAY 1000394 (Roniciclib) in Combination With Docetaxel in Second- or Third-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

Yonsei University

Phase 1/2 Withdrawn
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02390154 2016-07-15

Roniciclib Mass Balance Study

Bayer

Phase 1 Completed
7 enrolled
Tumor-Agnostic

Neoplasms

NCT02656849 2016-07-01

BAY 1000394 for MCL-1-, MYC-, and CCNE1-Amplified Tumors

Dana-Farber Cancer Institute

Phase 2 Withdrawn
Other solid neoplasm

Solid Tumor

NCT02457351 2016-05-23

Roniciclib (BAY 1000394) Drug-Drug Interaction (DDI) Study

Bayer

Phase 1 Completed
14 enrolled

Medical Oncology

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