Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 1/2 2Phase 1 1

Status

Recruiting 3Active not recruiting 2

Sponsor Class

OTHER 100INDUSTRY 38NIH 5NETWORK 4OTHER_GOV 1

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 3Sarcoma 2Plasma cell 1

Conditions

Glioblastoma 2Sarcoma, Alveolar Soft Part 1Multiple Myeloma 1Gliosarcoma 1Glioma 1

Interventions

Cyclophosphamide 385Specimen Handling 371Magnetic Resonance Spectroscopy 325Radiotherapy 306Biopsy 269Cisplatin 257Carboplatin 253Paclitaxel 235Doxorubicin 226Fluorouracil 200Etoposide 197Vincristine 182Bevacizumab 180Filgrastim 170Gemcitabine 163Leucovorin 149Cytarabine 144aldesleukin 140Taxes 127Docetaxel 122Oxaliplatin 113Chemotherapy, Adjuvant 113fludarabine phosphate 111Rituximab 107Methotrexate 107Radiation 106Bortezomib 105Prednisone 102Irinotecan 100Dexamethasone 100

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
NIH × Interventional × selinexor × Clear all
NCT05099003 2026-05-29

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

National Cancer Institute (NCI)

Phase 1/2 Recruiting
132 enrolled
CNS

Glioma

NCT05432804 2026-05-18

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

National Cancer Institute (NCI)

Phase 1/2 Recruiting
97 enrolled
CNS

Glioblastoma

NCT05333458 2026-05-13

Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial

National Cancer Institute (NCI)

Phase 2 Recruiting
27 enrolled
Sarcoma

Sarcoma, Alveolar Soft Part

NCT06169215 2026-05-13

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

National Cancer Institute (NCI)

Phase 2 Active not recruiting
70 enrolled
Plasma cell

Multiple Myeloma

NCT04216329 2026-01-23

Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1 Active not recruiting
11 enrolled 19 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

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