Announcements Trials
Browse Landscape

Phase

Phase 1 14Phase 2 6Phase 1/2 2Phase NA 1

Status

Completed 6Terminated 4Withdrawn 1Recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 4OTHER 2

Study Type

Interventional 6

Sponsor

Cancer Type

Dermatologic 3Plasma cell 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Carcinoma, Basal Cell 3Skin Neoplasms 2Recurrence 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Multiple Myeloma 1Medulloblastoma 1Leukemia, Myeloid, Acute 1Leukemia 1Basal Cell Nevus Syndrome 1

Interventions

Cyclophosphamide 741Cisplatin 688Gemcitabine 641Bevacizumab 616Carboplatin 605Paclitaxel 601Docetaxel 565Radiotherapy 536Fluorouracil 405Oxaliplatin 387Rituximab 369Doxorubicin 361Capecitabine 342Filgrastim 333Etoposide 330Dexamethasone 312Irinotecan 309pembrolizumab 282Leucovorin 274Cetuximab 268Cytarabine 242Erlotinib Hydrochloride 231Nivolumab 228Prednisone 227Trastuzumab 225Vincristine 221Bortezomib 221Methotrexate 207Pemetrexed 199fludarabine phosphate 195

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 2 × Completed × sonidegib × Clear all
NCT03534947 2025-12-16

SONIB

Melanoma Institute Australia

Phase 2 Completed
16 enrolled
Dermatologic

Carcinoma, Basal Cell, Skin Neoplasms

NCT02086552 2021-12-03

Sonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma

Mayo Clinic

Phase 2 Completed
28 enrolled 9 charts
Plasma cell

Multiple Myeloma

NCT01327053 2019-08-28

BOLT

Novartis

Phase 2 Completed
230 enrolled 26 charts
Dermatologic

Carcinoma, Basal Cell, Skin Neoplasms

NCT01708174 2017-08-11

A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)

Novartis

Phase 2 Completed
22 enrolled 12 charts
CNS

Medulloblastoma, Recurrence

NCT01826214 2016-08-30

Study of Efficacy and Safety of LDE225 in Adult Patients With Relapsed/Refractory Acute Leukemia

Novartis

Phase 2 Completed
70 enrolled 12 charts
LymphoidOther hematologic neoplasm

Leukemia, Recurrence, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01350115 2015-10-19

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Novartis

Phase 2 Completed
10 enrolled 9 charts
Dermatologic

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

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