Announcements Trials
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Phase

Phase 2 20Phase 1 14Phase 1/2 9Phase 3 5Phase EARLY_PHASE1 1Phase 4 1

Status

Recruiting 2Active not recruiting 2Completed 1

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 3Gastrointestinal 2

Conditions

Neoplasms 2Lung Neoplasms 2Colorectal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2KRAS p, G12c Mutated /Advanced Metastatic NSCLC 1

Interventions

Cisplatin 725Carboplatin 607Paclitaxel 578Cyclophosphamide 516Radiotherapy 511Docetaxel 475Fluorouracil 453Gemcitabine 437Doxorubicin 383Capecitabine 361Dexamethasone 327Oxaliplatin 288pembrolizumab 283Leucovorin 282Bevacizumab 275Etoposide 271Vincristine 270Rituximab 246Prednisone 222Pemetrexed 217Cytarabine 205Drug Therapy 194Trastuzumab 175Irinotecan 172Methotrexate 171Lenalidomide 137Nivolumab 135Filgrastim 135Epirubicin 129Tamoxifen 127

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 3 × sotorasib × Clear all
NCT05920356 2026-05-22

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

Amgen

Phase 3 Recruiting
750 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT04303780 2026-04-30

Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200).

Amgen

Phase 3 Active not recruiting
345 enrolled 11 charts
Thoracic

KRAS p, G12c Mutated /Advanced Metastatic NSCLC

NCT05198934 2026-04-27

CodeBreak300

Amgen

Phase 3 Completed
160 enrolled 1 FDA
Gastrointestinal

Colorectal Neoplasms

NCT06252649 2026-04-24

CodeBreaK 301

Amgen

Phase 3 Recruiting
450 enrolled
Gastrointestinal

Neoplasms, Colorectal Neoplasms

NCT06497556 2026-04-20

Krascendo 1

Hoffmann-La Roche

Phase 3 Active not recruiting
338 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

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