Clinical Trials Browser

Completed × Interventional × sotorasib × Clear all

Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation

NCT06333678 2026-01-29

A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)

Phase 2 Completed

10 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05054725 2026-01-06

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Phase 2 Completed

47 enrolled 17 charts

Thoracic

Bronchial Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Hereditary Sensory and Autonomic Neuropathies, Respiratory Tract Diseases, Respiratory Tract Neoplasms

NCT04933695 2025-10-22

CodeBreaK201

Phase 2 Completed

42 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04720976 2025-04-11

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

Phase 1/2 Completed

58 enrolled

Other solid neoplasmThoracic

Solid Tumor

NCT06314763 2024-04-30

ROSIE

Phase 4 Completed

21 enrolled

Classical hematologyThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Venous Thromboembolism

NCT05045638 2023-08-14

Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants

Phase 1 Completed

13 enrolled 14 charts

Healthy Participants

NCT04959981 2023-07-25

HERKULES-2

Phase 1 Completed

24 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Noonan Syndrome, Thoracic Neoplasms

Clinical Trials

AMG 510 Ethnic Sensitivity Study (CodeBreaK 105).

A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

CodeBreaK201

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

ROSIE

Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants

HERKULES-2