Clinical Trials Browser

Phase 2 × NIH × temsirolimus × Clear all

NCT00977574 2026-05-29

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Phase 2 Active not recruiting

349 enrolled 11 charts

GynecologicSarcoma

Endometrial Adenocarcinoma

NCT01767194 2022-10-24

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

Phase 2 Completed

73 enrolled 12 charts

Neuroblastoma, Ganglioneuroblastoma

NCT00376688 2020-02-24

Temsirolimus in Treating Patients With Locally Advanced or Metastatic Breast Cancer

Phase 2 Completed

31 enrolled 5 charts

Breast Neoplasms

NCT01196429 2019-08-08

Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer

Phase 2 Completed

90 enrolled 10 charts

Ovarian Neoplasms

NCT00429793 2019-07-24

Temsirolimus in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Completed

60 enrolled 13 charts

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms

NCT00723255 2019-07-23

Bevacizumab and Temsirolimus in Treating Patients With Recurrent or Persistent Endometrial Cancer

Phase 2 Completed

53 enrolled 15 charts

Endometrial Neoplasms

NCT00729586 2019-07-23

Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer

Phase 2 Completed

73 enrolled 13 charts

Endometrial Neoplasms

NCT01010126 2019-01-25

Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer

Phase 2 Completed

252 enrolled 20 charts

GastrointestinalGynecologic

Fallopian Tube Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Somatostatinoma

NCT01614795 2018-12-11

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Phase 2 Completed

46 enrolled 13 charts

Fibrosarcoma, Hemangiosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00378703 2018-11-14

Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer

Phase 2 Completed

361 enrolled 12 charts

Carcinoma, Renal Cell

NCT00397982 2017-06-09

Mel47

Phase 2 Completed

17 enrolled 12 charts

Melanoma

NCT01222715 2017-05-05

Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma

Phase 2 Completed

87 enrolled 11 charts

Rhabdomyosarcoma, Sarcoma

NCT01256385 2017-03-27

MAESTRO HN

Phase 2 Completed

86 enrolled 11 charts

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT00093782 2017-02-07

Temsirolimus in Treating Patients With Metastatic Neuroendocrine Carcinoma

Phase 2 Completed

36 enrolled 12 charts

Carcinoma, Islet Cell

NCT01061606 2016-11-09

Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus

Phase 2 Terminated

8 enrolled 6 charts

GynecologicSarcoma

Recurrent Uterine Sarcoma

NCT01206140 2015-10-05

Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery

Phase 2 Completed

70 enrolled 8 charts

Sarcoma

NCT01026792 2015-09-10

Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery

Phase 2 Completed

38 enrolled 5 charts

Uterine Cervical Neoplasms

NCT01016015 2015-07-30

Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma

Phase 2 Completed

178 enrolled 6 charts

Sarcoma, Osteosarcoma

NCT01851408 2015-04-15

Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma

Phase 2 Withdrawn

Melanoma, Recurrence

NCT00072176 2015-02-23

Temsirolimus in Treating Patients With Metastatic or Locally Advanced Recurrent Endometrial Cancer

Phase 2 Completed

62 enrolled 7 charts

Endometrial Neoplasms

NCT00290472 2014-05-23

CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

Phase 2 Completed

89 enrolled 9 charts

LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00281957 2014-05-20

Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery

Phase 2 Completed

109 enrolled 8 charts

Melanoma

NCT01166126 2014-05-15

Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV

Phase 2 Terminated

4 enrolled 7 charts

Melanoma

NCT00109967 2014-04-17

CCI-779 and Rituximab in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Phase 2 Completed

71 enrolled 10 charts

Lymphoma, Mantle-Cell

NCT00033267 2014-04-03

CCI-779 in Treating Patients With Mantle Cell Non-Hodgkin's Lymphoma

Phase 2 Completed

Lymphoma, Mantle-Cell

NCT00079456 2013-10-11

Temsirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma

Phase 2 Completed

Multiple Myeloma

NCT00016328 2013-07-18

CCI-779 in Treating Patients With Recurrent Glioblastoma Multiforme

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00079235 2013-07-16

CCI-779 in Treating Patients With Stage IIIB (With Pleural Effusion) or Stage IV Non-Small Cell Lung Cancer

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung

NCT00012142 2013-06-24

CCI-779 in Treating Patients With Prostate Cancer

Phase 2 Completed

Prostatic Neoplasms

NCT00087074 2013-06-04

CCI-779 in Treating Patients With Soft Tissue Sarcoma or Gastrointestinal Stromal Tumor

Phase 2 Completed

GastrointestinalSarcoma

Sarcoma, Gastrointestinal Stromal Tumors

NCT00028028 2013-02-28

CCI-779 in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Phase 2 Completed

Extensive Stage Small Cell Lung Cancer

NCT00086840 2013-01-24

CCI-779 in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia

Phase 2 Terminated

LymphoidOther hematologic neoplasm

Hodgkin Disease, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse

NCT00084916 2013-01-23

CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase

Phase 2 Completed

Classical hematologyLymphoidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00075647 2013-01-17

CCI-779 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Phase 2 Completed

Gastrointestinal

Pancreatic Neoplasms