Clinical Trials

33 enrolled 10 charts

Breast Neoplasms

NCT00021541 2018-04-17

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

62 enrolled 13 charts

CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT00005832 2015-11-17

S9924 R115777 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

58 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT00047216 2015-07-23

Tipifarnib in Treating Patients With Recurrent Bladder Cancer

Genitourinary

Urinary Bladder Neoplasms

NCT01361464 2015-04-08

Tipifarnib in Treating Older Patients With Acute Myeloid Leukemia

21 enrolled 8 charts

Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00602771 2014-10-09

Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed, Previously Untreated Acute Myeloid Leukemia

84 enrolled 7 charts

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00281957 2014-05-20

Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery

109 enrolled 8 charts

Dermatologic

Melanoma

NCT00006376 2013-12-04

R115777 in Treating Patients With Advanced Bladder Cancer

Genitourinary

Urinary Bladder Neoplasms

NCT00070525 2013-10-08

Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma

90 enrolled

CNS

Astrocytoma, Medulloblastoma, Oligodendroglioma, Optic Nerve Glioma

NCT00005848 2013-07-11

R115777 in Treating Patients With Progressive, Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

7 enrolled

Genitourinary

Prostatic Neoplasms

NCT00052728 2013-06-19

Tipifarnib Plus Tamoxifen in Treating Women With Metastatic Breast Cancer

Breast Neoplasms

NCT00049114 2013-06-06

Tipifarnib, Doxorubicin, and Cyclophosphamide in Treating Women With Locally Advanced Breast Cancer

62 enrolled

Breast Neoplasms, Inflammatory Breast Neoplasms

NCT00060125 2013-06-05

Tipifarnib in Treating Patients With Metastatic Malignant Melanoma

40 enrolled

Dermatologic

Melanoma

NCT00047190 2013-06-04

Tipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia

35 enrolled

Myeloid

Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

NCT00055757 2013-06-04

Tipifarnib, Gemcitabine, and Cisplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

48 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00025038 2013-04-11

Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia

100 enrolled

Leukemia, Myelomonocytic, Juvenile

NCT00058097 2013-04-09

Tipifarnib and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

54 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT00027872 2013-03-25

Tipifarnib in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

125 enrolled

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00077363 2013-02-27

Capecitabine and Tipifarnib in Treating Women With Taxane-Resistant Metastatic Breast Cancer

70 enrolled

Breast Neoplasms

NCT00005843 2013-02-11

R115777 in Treating Patients Who Have Metastatic Pancreatic Cancer

40 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT00050141 2013-02-01

Study of Letrozole Plus Tipifarnib or Placebo in the Treatment of Advanced Breast Cancer

121 enrolled

Breast Neoplasms

NCT00093418 2013-01-15

S0432 Tipifarnib in Treating Older Patients With Acute Myeloid Leukemia

296 enrolled

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00005041 2012-11-09

R115777 in Treating Patients With Relapsed Small Cell Lung Cancer

Thoracic

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00012350 2012-10-23

Phase II Evaluation of FTase Inhibitor (FTI)in Treatment of Advanced Multiple Myeloma

44 enrolled

Plasma cell

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00005833 2012-06-14

S9923 R115777 in Treating Patients With Advanced Colorectal Cancer

62 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00209989 2011-11-24

Phase II Trial to Assess the Radiosensitizing Effect of ZARNESTRA in Patients With Glioblastoma Multiforme

27 enrolled

CNS

Glioblastoma

NCT00005989 2011-08-04

R115777 in Treating Patients With Recurrent or Metastatic Non-small Cell Lung Cancer

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00354146 2011-02-01

A Phase 2 Study of Farnesyl Transferase Inhibitor (R115777, Tipifarnib) in Patients With Refractory or Relapsed Acute Myeloid Leukemia.

252 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT00048503 2010-04-27

Study of Tipifarnib as Postconsolidation Therapy for Acute Myeloid Leukemia in Patients 60 Years and Older

88 enrolled