Announcements Trials
Browse Landscape

Phase

Phase 2 5Phase 1/2 2

Status

Terminated 4Completed 2Unknown 1

Sponsor Class

INDUSTRY 7OTHER 2

Study Type

Interventional 7

Sponsor

Cancer Type

Gastrointestinal 2Thoracic 1Other solid neoplasm 1Lymphoid 1Head & Neck 1Genitourinary 1Dermatologic 1Breast 1

Conditions

Triple Negative Breast Neoplasms 1Thyroid Diseases 1Solid Tumors 1Prostatic Neoplasms 1Neoplasms 1Melanoma 1Lymphoma 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Hepatocellular 1

Interventions

pembrolizumab 1033Carboplatin 971Paclitaxel 942Gemcitabine 799Cisplatin 757Docetaxel 698Bevacizumab 637Nivolumab 520Pemetrexed 507Capecitabine 475Cyclophosphamide 473Fluorouracil 425Dexamethasone 410Rituximab 391Oxaliplatin 352Injections 347Trastuzumab 313atezolizumab 312Cetuximab 291Leucovorin 290Irinotecan 271130-nm albumin-bound paclitaxel 257Prednisone 251Ipilimumab 244Doxorubicin 241Lenalidomide 231Fulvestrant 226fludarabine 219durvalumab 211Erlotinib Hydrochloride 196

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
INDUSTRY × tomivosertib × Clear all
NCT03690141 2024-06-21

An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer

Effector Therapeutics

Phase 2 Terminated
16 enrolled 9 charts
Genitourinary

Prostatic Neoplasms

NCT04622007 2024-04-30

KICKSTART

Effector Therapeutics

Phase 2 Unknown
68 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03616834 2023-03-22

Tomivosertib (eFT-508) in Combination With PD-1/PD-L1 Inhibitor Therapy

Effector Therapeutics

Phase 2 Completed
39 enrolled
Other solid neoplasm

Solid Tumors

NCT02605083 2020-11-02

A Dose Escalation and Cohort-Expansion Study of Oral eFT508 in Subjects With Advanced Solid Tumors

Effector Therapeutics

Phase 1/2 Terminated
66 enrolled
DermatologicHead & Neck

Melanoma, Neoplasms, Thyroid Diseases

NCT02937675 2020-11-02

A Phase 1-2 Dose-Escalation and Cohort-Expansion Study of Oral Tomivosertib (eFT-508) in Subjects With Hematological Malignancies

Effector Therapeutics

Phase 1/2 Terminated
28 enrolled
Lymphoid

Lymphoma

NCT03258398 2019-07-18

A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer

Effector Therapeutics

Phase 2 Completed
56 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT03318562 2019-07-18

A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC

Effector Therapeutics

Phase 2 Terminated
3 enrolled
BreastGastrointestinal

Carcinoma, Hepatocellular, Triple Negative Breast Neoplasms

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