Clinical Trials
60 trialsPersonalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
National Cancer Institute (NCI)
A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma
AstraZeneca
DG-03
AstraZeneca
Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma
National Cancer Institute (NCI)
DL-05
AstraZeneca
A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors
AstraZeneca
A Trial of Trastuzumab Rezetecan in Unresectable Locally Recurrent/Metastatic Breast Cancer
Jiangsu HengRui Medicine Co., Ltd.
TUXEDO-4
MedSIR
Trial of Trastuzumab Deruxtecan in Previously Treated HER2
Yale University
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers
NRG Oncology
DEMETHER
MedSIR
Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction
Brown University
TROY
Yonsei University
DPT02
AstraZeneca
Phase 2 Study of Trastuzumab Deruxtecan in the Neoadjuvant Treatment, or Trastuzumab Deruxtecan Plus Capecitabine Plus Durvalumab(MEDI4736) in the Preoperative and Postoperative Adjuvant Treatment for Patients With HER2 Positive Gastric and Gastroesophageal Junction Adenocarcinoma
National Cancer Center Hospital East
TRANSCENDER
Spanish Breast Cancer Research Group
PONTIAC
MedSIR
TOP-REAL
SOLTI Breast Cancer Research Group
HER2CLIMB-04
Seagen Inc.
DPT01
AstraZeneca
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)
Gruppo Oncologico del Nord-Ovest
Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer
Memorial Sloan Kettering Cancer Center
HERCULES
Memorial Sloan Kettering Cancer Center
Trastuzumab Rezetecan vs Trastuzumab Deruxtecan in the Neoadjuvant Treatment of HER2 Positive Breast Cancer
Henan Cancer Hospital
CHIMERA
Gruppo Oncologico del Nord-Ovest
ELPIS
Yonsei University
Neoadjuvant Trastuzumab Deruxtecan (SHR-A1811) + Pertuzumab in HER2+ Breast Cancer
Shanghai Jiao Tong University School of Medicine
STORM
Fudan University
DESTINY-CRC02
Daiichi Sankyo
Trastuzumab Deruxtecan to Treat HER2 + Newly Diagnosed Metastatic GI Cancers
University of Chicago
Perioperative Therapies in Locally Advanced Unresectable Gastric Cancer
Samsung Medical Center
Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
ANISE
The Netherlands Cancer Institute
DESTINY-LUNG02
Daiichi Sankyo
Scalp Cooling in MBC
Dana-Farber Cancer Institute
ADAPTHER2-IV
West German Study Group
Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer
Jonsson Comprehensive Cancer Center
HUDSON
AstraZeneca
TRADE DXd
Dana-Farber Cancer Institute
TRUDI
Dana-Farber Cancer Institute
ALTER
UNICANCER
THUNDER
Fudan University
ARIADNE
Karolinska University Hospital
THUMB
Fudan University
DESTINY-Breast01
Daiichi Sankyo
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
Dana-Farber Cancer Institute
DEBBRAH
MedSIR
A Phase II Study of HLX22 in Combination With Trastuzumab Deruxtecan in HER2-low, Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer Patients
Shanghai Henlius Biotech
DAISY
UNICANCER
DESTINY-Lung01
Daiichi Sankyo