Clinical Trials Browser

Observational × trastuzumab deruxtecan × Clear all

NCT06551220 2026-05-22

HEROIC

Breast Neoplasms

NCT06663787 2026-05-13

HER2 CR

Active not recruiting

Breast Neoplasms, Neoplasm Metastasis, Neoplasm, Residual

NCT07582887 2026-05-13

Impact of Genetic Variants on the Toxicity of Antibody-Drug Conjugates in Locally Advanced or Metastatic Breast Cancer: The Role of the UGT1A1 Gene as a Predictive Biomarker of Therapeutic Response

Breast Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT05993234 2026-05-08

A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)

Gastrointestinal

HER2-positive Advanced Gastric Cancer

NCT07124000 2026-05-01

DP-04

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Adenocarcinoma, Anus Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Melanoma, Mouth Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma

NCT05945732 2026-02-12

DESTINY Breast Respond HER2-low Europe

Breast Neoplasms

NCT06210776 2026-01-12

A Study to Assess the Effectiveness of Trastuzumab Deruxtecan in Chinese Breast Cancer Patients (REFRESH)

Breast Neoplasms

NCT07180264 2025-11-18

Trastuzumab Deruxtecan in Advanced Breast Cancer

Advanced Breast Cancer

NCT06386263 2025-10-15

HER-TEMPO

Breast Neoplasms

NCT06504719 2025-09-15

Safety and Efficacy Real-world Data of Trastuzumab Deruxtecan and Sacituzumab Govitecan

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT06846996 2025-07-08

RECOVER

Gastrointestinal

HER2-positive Gastric Cancer

NCT06727227 2025-07-01

EXPLORE

Breast Neoplasms

NCT07035353 2025-06-25

A Real-world Clinical Study of T-DXd for the Treatment of Chinese Patients With HER2 Overexpressing and HER2 Underexpressing Advanced Breast Cancer

Not yet recruiting

HER2 Overexpression

NCT07030569 2025-06-22

RADIOSPHER2

Breast Neoplasms

NCT06231693 2025-05-08

Trastuzumab-deruxtecan in Patients With Triple-negative Metastatic HER2-Low Breast Cancer: Real-world Experience in Brazil

Breast Neoplasms

NCT05458401 2024-03-15

EUROPA T-DXd

HER2-positive Breast Cancer

NCT06135194 2023-11-18

Efficacy of T-Dxd in the Treatment of HER2-positive BCBM After Prior Pyrotinib

Breast Neoplasms

NCT05594082 2023-04-04

Real-world Effectiveness and Safety Study of T-Dxd in Chinese Metastatic Breast Cancer

Breast Neoplasms