Announcements Trials
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Phase

Phase 2 6Phase 3 4Phase 4 2Phase 1/2 2

Status

Terminated 4Completed 2

Sponsor Class

OTHER 19INDUSTRY 6OTHER_GOV 1

Study Type

Interventional 6

Sponsor

Cancer Type

Breast 3Thoracic 2Genitourinary 1

Conditions

Triple Negative Breast Neoplasms 3Neoplasm Metastasis 2Breast Neoplasms 2Urinary Bladder Neoplasms 1Small Cell Lung Carcinoma 1Lung Neoplasms 1Carcinoma, Transitional Cell 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Carboplatin 273Paclitaxel 267Gemcitabine 244Bevacizumab 226Cisplatin 218pembrolizumab 214Docetaxel 210Pemetrexed 162Capecitabine 148Fluorouracil 129Oxaliplatin 121Cyclophosphamide 121Nivolumab 112Dexamethasone 100Trastuzumab 89Leucovorin 87Cetuximab 85Rituximab 83Irinotecan 82Injections 81Erlotinib Hydrochloride 70Prednisone 68Doxorubicin 68Temozolomide 67atezolizumab 65Bortezomib 65Ipilimumab 64Fulvestrant 59Radiotherapy 54Drug Therapy 51

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 2 × INDUSTRY × trilaciclib × Clear all
NCT03041311 2025-09-25

Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLC

G1 Therapeutics, Inc.

Phase 2 Completed
107 enrolled 42 charts
Thoracic

Small Cell Lung Carcinoma

NCT04887831 2025-09-08

PRESERVE3

G1 Therapeutics, Inc.

Phase 2 Terminated
92 enrolled 24 charts
Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT05113966 2025-01-29

Trilaciclib in Patients Receiving Sacituzumab Govitecan-hziy for Triple Negative Breast Cancer

G1 Therapeutics, Inc.

Phase 2 Terminated
30 enrolled 16 charts
Breast

Triple Negative Breast Neoplasms

NCT05112536 2024-03-12

Trilaciclib, a CDK4/6 Inhibitor, in Patients With Early-Stage Triple Negative Breast Cancer

G1 Therapeutics, Inc.

Phase 2 Completed
24 enrolled 17 charts
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04863248 2023-04-14

PRESERVE 4

G1 Therapeutics, Inc.

Phase 2 Terminated
10 enrolled 14 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT02978716 2022-03-23

Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Gemcitabine and Carboplatin in Metastatic Triple Negative Breast Cancer (mTNBC)

G1 Therapeutics, Inc.

Phase 2 Terminated
102 enrolled 51 charts
Breast

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

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