Announcements Trials
Browse Landscape

Phase

Phase 2 12Phase 1 5Phase 3 1

Status

Completed 5

Sponsor Class

INDUSTRY 4NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Other solid neoplasm 3Tumor-Agnostic 1Head & Neck 1Genitourinary 1Gastrointestinal 1Endocrine 1CNS 1

Conditions

Solid Tumors 2Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1Squamous Cell Carcinoma of Head and Neck 1Salivary Gland Neoplasms 1Parathyroid Neoplasms 1Neoplasms 1Kidney Neoplasms 1Head and Neck Neoplasms 1Esthesioneuroblastoma, Olfactory 1Colorectal Neoplasms 1Colonic Neoplasms 1Carcinoma, Renal Cell 1Carcinoma, Medullary 1Advanced Solid Tumors 1Adenocarcinoma, Follicular 1

Interventions

Paclitaxel 291Gemcitabine 254Carboplatin 253Cisplatin 250Radiotherapy 219Cyclophosphamide 218Irinotecan 184pembrolizumab 180Docetaxel 174Bevacizumab 166Capecitabine 148Nivolumab 141Fluorouracil 132Dexamethasone 125Bortezomib 123Oxaliplatin 115Cytarabine 113Erlotinib Hydrochloride 112Temozolomide 110Sorafenib 110Doxorubicin 106Rituximab 105Leucovorin 105Etoposide 105Filgrastim 99Everolimus 97Lenalidomide 95Ipilimumab 90Pemetrexed 89fludarabine phosphate 84

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × Completed × tumor necrosis factor-alpha, CNGRC fusion protein, human × Clear all
NCT00419328 2022-07-21

A Modified Phase I Study of NGR-hTNF in Advanced Solid Tumors

AGC Biologics S.p.A.

Phase 1 Completed
16 enrolled
Other solid neoplasm

Advanced Solid Tumors

NCT00305084 2019-10-04

Study of NGR-hTNF in Combination With Doxorubicin in Solid Tumors

AGC Biologics S.p.A.

Phase 1 Completed
15 enrolled 20 charts
Tumor-Agnostic

Neoplasms

NCT00878111 2018-08-29

Study of NGR-hTNF Administered at High Doses in Patient With Advanced or Metastatic Solid Tumour

AGC Biologics S.p.A.

Phase 1 Completed
48 enrolled
Other solid neoplasm

Solid Tumors

NCT00483093 2014-05-30

Study of NGR-hTNF in Combination With Cisplatin in Solid Tumor

AGC Biologics S.p.A.

Phase 1 Completed
22 enrolled
Other solid neoplasm

Solid Tumors

NCT00098943 2012-09-24

NGR-TNF in Treating Patients With Advanced Solid Tumors

European Organisation for Research and Treatment of Cancer - EORTC

Phase 1 Completed
70 enrolled
CNSEndocrineGastrointestinalGenitourinaryHead & Neck

Squamous Cell Carcinoma of Head and Neck, Thyroid Cancer, Papillary, Carcinoma, Renal Cell, Colonic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Parathyroid Neoplasms, Salivary Gland Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Thyroid Carcinoma, Anaplastic

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