Clinical Trials Browser

Phase 2 × INDUSTRY × vandetanib × Clear all

NCT00537095 2024-04-19

Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer

Phase 2 Completed

164 enrolled 10 charts

Head & Neck

Thyroid Neoplasms

NCT00098345 2018-05-07

Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer

Phase 2 Completed

40 enrolled 12 charts

Head & Neck

Thyroid Neoplasms

NCT00500292 2018-01-25

A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal Cancer

Phase 2 Completed

109 enrolled 8 charts

Tumor-Agnostic

Neoplasms

NCT00358956 2017-01-30

A Study To Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer

Phase 2 Completed

19 enrolled 10 charts

EndocrineHead & Neck

Familial medullary thyroid carcinoma, Thyroid Neoplasms, Carcinoma, Medullary

NCT00686036 2016-12-21

ZENITH

Phase 2 Terminated

17 enrolled 4 charts

Genitourinary

Prostatic Neoplasms

NCT00659438 2016-12-05

Efficacy and Safety of Zactima™ in Patients With Castration-refractory Metastatic Prostate Cancer

Phase 2 Completed

95 enrolled 12 charts

Genitourinary

Prostatic Neoplasms

NCT00752986 2016-12-05

ZACFAST

Phase 2 Terminated

39 enrolled 7 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT00753714 2016-10-17

ZELIG

Phase 2 Completed

124 enrolled 11 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT00508001 2016-10-10

Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC)

Phase 2 Completed

67 enrolled 12 charts

Gastrointestinal

Carcinoma, Hepatocellular, Neoplasms

NCT00597116 2016-10-10

An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesothelioma

Phase 2 Terminated

25 enrolled 8 charts

Other solid neoplasmThoracic

Mesothelioma, Recurrence

NCT00753675 2016-10-10

VANGOGH

Phase 2 Completed

174 enrolled 12 charts

Gastrointestinal

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT00777179 2016-10-10

Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet Chemotherapy

Phase 2 Completed

117 enrolled 15 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00454116 2016-10-07

A Phase II, Double Blind Study of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients

Phase 2 Completed

106 enrolled 8 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00498797 2016-10-07

E3-Hormone Refractory Prostrate Cancer Taxotere Combination

Phase 2 Completed

86 enrolled 8 charts

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms

NCT00494481 2016-09-30

E3 Breast Cancer Taxotere Combination

Phase 2 Completed

64 enrolled 7 charts

Breast

Advanced Breast Cancer

NCT00047840 2016-08-25

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.

Phase 2 Completed

129 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00071188 2016-08-25

ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

Phase 2 Completed

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00252746 2016-08-25

ZD6474 Phase IIa Dose Finding Multicentre Study

Phase 2 Completed

53 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00034918 2016-08-24

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Metastatic Breast Cancer

Phase 2 Completed

44 enrolled

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT00047788 2016-08-24

Efficacy Study of ZD6474 to Treat Multiple Myeloma Cancer

Phase 2 Completed

30 enrolled

Plasma cell

Multiple Myeloma

NCT00059722 2016-08-24

This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.

Phase 2 Completed

160 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00066313 2016-08-24

ZD6474 in Treating Patients With Small Cell Lung Cancer

Phase 2 Completed

Thoracic

Lung Neoplasms