Clinical Trials
44 trialsNCT01298323 2026-04-17
Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment
Sanofi
Phase 3 Completed
NCT04211337 2026-03-19
LIBRETTO-531
Eli Lilly and Company
Phase 3 Active not recruiting
NCT01496313 2025-10-03
To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid Cancer
Sanofi
Phase 4 Completed
NCT00410761 2025-09-24
An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer
Sanofi
Phase 3 Completed
NCT00418886 2024-12-31
ZEAL
Sanofi
Phase 3 Completed
NCT01876784 2024-07-23
VERIFY
Sanofi
Phase 3 Completed
NCT00537095 2024-04-19
Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer
Sanofi
Phase 2 Completed
NCT04760288 2024-01-05
AcceleRET-MTC
Hoffmann-La Roche
Phase 3 Withdrawn
NCT00098345 2018-05-07
Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer
Sanofi
Phase 2 Completed
NCT00364351 2018-01-25
Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy
Sanofi
Phase 3 Completed
NCT00500292 2018-01-25
A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal Cancer
Sanofi
Phase 2 Completed
NCT01539655 2017-05-02
Vandetanib
Sanofi
Phase 1 Completed
NCT00358956 2017-01-30
A Study To Assess ZD6474 (ZACTIMAâ„¢) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer
Sanofi
Phase 2 Completed
NCT00686036 2016-12-21
ZENITH
Sanofi
Phase 2 Terminated
NCT00659438 2016-12-05
Efficacy and Safety of Zactimaâ„¢ in Patients With Castration-refractory Metastatic Prostate Cancer
Sanofi
Phase 2 Completed
NCT00752986 2016-12-05
ZACFAST
Sanofi
Phase 2 Terminated
NCT01661179 2016-12-05
Evaluate the Safety and Tolerability of Vandetanib in Japanese Patients With Medullary Thyroid Carcinoma
Sanofi
Phase 1/2 Completed
NCT00753714 2016-10-17
ZELIG
Sanofi
Phase 2 Completed
NCT00508001 2016-10-10
Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC)
Sanofi
Phase 2 Completed
NCT00597116 2016-10-10
An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesothelioma
Sanofi
Phase 2 Terminated
NCT00753675 2016-10-10
VANGOGH
Sanofi
Phase 2 Completed
NCT00777179 2016-10-10
Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet Chemotherapy
Sanofi
Phase 2 Completed
NCT00862836 2016-10-10
ZACFAST
Sanofi
Phase 1/2 Terminated
NCT00454116 2016-10-07
A Phase II, Double Blind Study of 2 Doses of ZACTIMAâ„¢(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients
Sanofi
Phase 2 Completed
NCT00498797 2016-10-07
E3-Hormone Refractory Prostrate Cancer Taxotere Combination
Sanofi
Phase 2 Completed
NCT00312377 2016-09-30
ZODIAC
Sanofi
Phase 3 Completed
NCT00404924 2016-09-30
ZD6474 (ZACTIMAâ„¢) Phase III Study in EGFR Failures
Sanofi
Phase 3 Completed
NCT00494481 2016-09-30
E3 Breast Cancer Taxotere Combination
Sanofi
Phase 2 Completed
NCT00503711 2016-08-31
Phase I Chinese PK
Sanofi
Phase 1 Completed
NCT00450138 2016-08-29
Open Label, Phase I ZD6474 Head and Neck Cancer Study
Sanofi
Phase 1 Completed
NCT00681798 2016-08-29
Dose Escalation Study With Zactima and Chemotherapy in Metastatic Pancreas Carcinoma
Sanofi
Phase 1 Completed
NCT00807170 2016-08-29
Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases
Sanofi
Phase 1 Terminated
NCT00496275 2016-08-26
Phase I Combination With Vinorelbine or Gemcitabine Plus Cisplatin in Locally Advanced or Metastatic NSCLC
Sanofi
Phase 1 Completed
NCT00496509 2016-08-26
Phase I Efficacy On Vascular Permeability In Patients With Advanced Colorectal Cancer
Sanofi
Phase 1 Completed
NCT00047840 2016-08-25
This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.
Sanofi
Phase 2 Completed
NCT00071188 2016-08-25
ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Sanofi
Phase 2 Completed
NCT00252746 2016-08-25
ZD6474 Phase IIa Dose Finding Multicentre Study
Sanofi
Phase 2 Completed
NCT00499850 2016-08-25
Phase I FOLFOX Combination
Sanofi
Phase 1 Completed
NCT00506051 2016-08-25
ZD6474(Vandetanib) + Alimta Combo Study
Sanofi
Phase 1 Completed
NCT00507091 2016-08-25
Phase I Irinotecan, 5-Fluorouracil and Leucovorin Combination
Sanofi
Phase 1 Completed
NCT00034918 2016-08-24
This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Metastatic Breast Cancer
Sanofi
Phase 2 Completed
NCT00047788 2016-08-24
Efficacy Study of ZD6474 to Treat Multiple Myeloma Cancer
Sanofi
Phase 2 Completed
NCT00059722 2016-08-24
This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.
Sanofi
Phase 2 Completed
NCT00066313 2016-08-24
ZD6474 in Treating Patients With Small Cell Lung Cancer
Sanofi
Phase 2 Completed