Clinical Trials Browser

Urothelial Cancer

NCT07419295 2026-04-13

TroFuse-031

Phase 3 Recruiting

590 enrolled

Genitourinary

Urinary Bladder Neoplasms

NCT03474107 2026-01-09

A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301)

Phase 3 Completed

608 enrolled 22 charts 2 FDA

Genitourinary

Urinary Bladder Neoplasms, Ureteral Neoplasms

NCT04527991 2025-08-03

TROPiCS-04

Phase 3 Completed

712 enrolled

Genitourinary

Locally Advanced or Metastatic Unresectable Urothelial Cancer

NCT01095003 2022-04-28

Trial of Vinflunine Plus Capecitabine in Advanced Breast Cancer

Phase 3 Completed

770 enrolled 13 charts

Breast

Breast Neoplasms

NCT02256436 2021-09-20

MK-3475-045

Phase 3 Completed

542 enrolled 31 charts

Genitourinary

Parkinson Disease 4, Autosomal Dominant Lewy Body, Urinary Bladder Neoplasms

NCT01091168 2019-09-16

Trial of Vinflunine Versus Alkylating Agent in Metastatic Breast Cancer

Phase 3 Completed

594 enrolled 11 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT02302807 2019-08-01

A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

Phase 3 Completed

931 enrolled 21 charts

Genitourinary

Urinary Bladder Neoplasms

NCT01953003 2019-05-02

Phase III Study of Vinflunine Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer

Phase 3 Completed

112 enrolled 11 charts

Breast

Breast Neoplasms

NCT02347332 2019-03-05

Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer

Phase 3 Completed

459 enrolled 13 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Recurrence

NCT02845050 2018-02-13

JaNEO

Phase 1/2 Withdrawn

Genitourinary

Urinary Bladder Neoplasms

NCT00362830 2016-09-19

A Study of the Alternative Administration of Ixabepilone and Vinflunine

Phase 1 Completed

60 enrolled

Tumor-Agnostic

Neoplasms

NCT00388557 2016-09-19

Effect of Ketoconazole on the Pharmacokinetics of Vinflunine

Phase 1 Completed

35 enrolled

Tumor-Agnostic

Neoplasms

NCT01599013 2015-12-08

JASINT1

Phase 2 Completed

69 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Neoplasm Metastasis, Urogenital Neoplasms, Urologic Neoplasms, Renal Insufficiency

NCT00389155 2015-12-07

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Phase 2/3 Completed

34 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Neoplasm Metastasis

NCT00534807 2015-09-01

A Study of the Interaction of Rifampin and Vinflunine in Subjects With Advanced Cancer

Phase 1 Withdrawn

Tumor-Agnostic

Neoplasms

NCT00101608 2010-03-02

Vinflunine in Patients With Locally Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium

Phase 2 Completed

150 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Kidney Neoplasms, Ureteral Neoplasms

NCT00359476 2010-03-02

A Study of Vinflunine in Patients With Gastric Cancer

Phase 2/3 Terminated

55 enrolled

Gastrointestinal

Stomach Neoplasms

NCT00315237 2010-01-07

Phase III Trial of Vinflunine Plus Best Supportive Care vs. Best Supportive Care in Patients With Transitional Cell Carcinoma (TCC) of the Urothelial Tract

Phase 3 Completed

364 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

Clinical Trials

THOR

TroFuse-031

A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301)

TROPiCS-04

Trial of Vinflunine Plus Capecitabine in Advanced Breast Cancer

MK-3475-045

Trial of Vinflunine Versus Alkylating Agent in Metastatic Breast Cancer

A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

Phase III Study of Vinflunine Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer

Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer

JaNEO

A Study of the Alternative Administration of Ixabepilone and Vinflunine

Effect of Ketoconazole on the Pharmacokinetics of Vinflunine

JASINT1

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

A Study of the Interaction of Rifampin and Vinflunine in Subjects With Advanced Cancer

Vinflunine in Patients With Locally Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium

A Study of Vinflunine in Patients With Gastric Cancer

Phase III Trial of Vinflunine Plus Best Supportive Care vs. Best Supportive Care in Patients With Transitional Cell Carcinoma (TCC) of the Urothelial Tract