Clinical Trials

48 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05839626 2026-05-27

A Study to Investigate Safety and Efficacy With SAR445514 in Participants With Relapsed/Refractory Multiple Myeloma (RRMM) and Relapsed/Refractory Light-chain Amyloidosis (RRLCA)

Phase 1 Terminated

32 enrolled

Plasma cell

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT05870579 2026-05-27

[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

48 enrolled

Breast Neoplasms

NCT06077500 2026-05-27

DAREONᵀᴹ-8

46 enrolled

Thoracic

Small Cell Lung Carcinoma

NCT06120283 2026-05-27

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

399 enrolled

BreastThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT06132113 2026-05-27

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

55 enrolled

Endocrine

Neuroendocrine Neoplasms

NCT06248411 2026-05-27

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

189 enrolled

Advanced or Metastatic Solid Tumors

NCT06458712 2026-05-27

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

180 enrolled

CNS

Kenny-Caffey syndrome, Type 1, Anophthalmia with pulmonary hypoplasia, Brain Neoplasms

NCT06496568 2026-05-27

A Study Evaluating Single-agent Inavolisib, Inavolisib Plus Atezolizumab in PIK3CA-Mutated Cancers

30 enrolled

PIK3CA-Mutated Cancers

NCT06619873 2026-05-27

A Clinical Study to Evaluate the Relative Bioavailability and Food Effect of HRS-8080 in Healthy Subjects

Phase 1 Completed

24 enrolled

Breast Neoplasms

NCT06714591 2026-05-27

Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1

Other hematologic neoplasm

120 enrolled

Leukemia, Myeloid, Acute

NCT06880549 2026-05-27

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

42 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence

NCT07073547 2026-05-27

A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

40 enrolled

Plasma cell

Multiple Myeloma

NCT07226349 2026-05-27

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

105 enrolled

Advanced Solid Tumor

NCT07306559 2026-05-27

A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)

187 enrolled

Gynecologic

Ovarian Neoplasms, Endometrial Neoplasms

NCT07407504 2026-05-27

GenSci145 as Monotherapy or in Combination Therapy, in Participants With PIK3CA-mutated, Locally Advanced or Metastatic Solid Tumors.

186 enrolled

Locally Advanced or Metastatic Solid Tumors With PIK3CA-mutated

NCT07414836 2026-05-27

A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors

84 enrolled

Advanced Solid Tumor

NCT07438782 2026-05-27

First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors

97 enrolled

Tumor-Agnostic

Neoplasms

NCT07604571 2026-05-27

Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer

194 enrolled

Advanced HR+/HER2- Breast Cancer

NCT07607678 2026-05-27

A Study in People With Advanced Cancer to Test How Well Different Doses of BI 3819026 Are Tolerated When Taken Alone and Together With Ezabenlimab

60 enrolled

Unresectable Advanced or Metastatic Solid Cancer

NCT07609706 2026-05-27

A Study of the Combination of Belantamab Mafodotin, Bortezomib, and Dexamethasone (BVd) in Participants With Multiple Myeloma and Moderate Hepatic Impairment

20 enrolled

Plasma cell

Multiple Myeloma

NCT07610148 2026-05-27

A Study to Estimate Effect of Formulation and Food on Relative Bioavailability of HRS-6209 in Healthy Participants

21 enrolled

Breast Neoplasms

NCT04250155 2026-05-26

An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

195 enrolled

Solid Tumors

NCT04929223 2026-05-26

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

542 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT05067283 2026-05-26

KANDLELIT-001

830 enrolled

Advanced Solid Tumors

NCT06147037 2026-05-26

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

GastrointestinalGenitourinaryHead & NeckThoracic

70 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Stomach Neoplasms, Colorectal Neoplasms

NCT06492122 2026-05-26

ProTACT

50 enrolled

Genitourinary

Metastatic Castration-resistant Prostate Cancer

NCT06533059 2026-05-26

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

BreastGenitourinaryGynecologic

110 enrolled

Breast Neoplasms, Uterine Cervical Neoplasms, Genital Neoplasms, Female, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06596473 2026-05-26

A Study of BG-C477 in Participants With Advanced Solid Tumors

310 enrolled

Advanced Solid Tumors

NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

GastrointestinalGynecologicThoracic

750 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07128303 2026-05-26

Study of GS-5319 in Adults With Solid Tumors

178 enrolled

Advanced Solid Tumor

NCT07176975 2026-05-26

A Study to Test How Well Different Doses of BI 1831169 in Combination With an Anti-PD1 Antibody Are Tolerated in Japanese People With Different Advanced Cancers

46 enrolled

Solid Tumors

NCT07181681 2026-05-26

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

63 enrolled

Solid Tumors

NCT07226427 2026-05-26

A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer

100 enrolled

Gynecologic

Ovarian Neoplasms

NCT07572006 2026-05-26

A Study of JNJ-95804306 for Relapsed or Refractory Hematological Malignancies

Other hematologic neoplasm

280 enrolled

Hematologic Neoplasms

NCT07606612 2026-05-26

A Study of SI-B036 in Patients With Locally Advanced or Metastatic Solid Tumors

31 enrolled

Solid Tumor

NCT07607054 2026-05-26

A First-in-human Phase I Study to Evaluate EMB-15 in Patients With Locally Advanced or Metastatic Solid Tumors.

50 enrolled

Locally Advanced or Metastatic Solid Tumors

NCT02632708 2026-05-22

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Other hematologic neoplasm

153 enrolled

Leukemia, Myeloid, Acute

NCT03715933 2026-05-22

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

411 enrolled

Sarcoma

Sarcoma, Sarcoma, Ewing

NCT04277637 2026-05-22

Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies

437 enrolled

Lymphoid

Mature B-Cell Malignancies

NCT04846920 2026-05-22

MK-6482-018

Phase 1 Completed

29 enrolled

Genitourinary

Carcinoma, Renal Cell

NCT05109728 2026-05-22

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

65 enrolled

CNS

Glioblastoma

NCT05277051 2026-05-22

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

152 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05362773 2026-05-22

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

LymphoidMyeloidOther hematologic neoplasm

130 enrolled

Blastic Plasmacytoid Dendritic Cell Neoplasm, Leukemia, Hairy Cell, Myelodysplastic Syndromes, Leukemia, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Mastocytosis, Systemic

NCT05464030 2026-05-22

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

200 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT05839600 2026-05-22

A Study to Find a Suitable Dose of BI 1821736 and Test Whether it Helps People With Advanced Cancer

Phase 1 Terminated

10 enrolled 12 charts