Clinical Trials Browser

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NCT07395258 2026-06-04

A Study to Test Different Doses of BI 3923948 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

Phase 1 Suspended

Other solid neoplasm

Solid Tumors

NCT05155332 2026-05-20

A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

Phase 1 Suspended

Other solid neoplasm

Solid Tumors

NCT02354547 2026-05-08

A Study of SGT-53 in Children With Refractory or Recurrent Solid Tumors

Phase 1 Suspended

Neoplasms

NCT07529535 2026-04-17

A First-in-Human Study of ALK-N001 for Injection in Patients With Advanced Solid Tumors

Phase 1 Suspended

Other solid neoplasm

Advance Solid Tumors

NCT06388902 2025-11-21

A Phase I Study of BR115 for Injection Alone in Subjects With Advanced Solid Malignancies

Phase 1 Suspended

Advanced Solid Malignancies

NCT05938296 2025-11-19

oHSV2-PD-L1/CD3-BsAb Administered Via Intratumoral Injection

Phase 1 Suspended

Other solid neoplasm

Solid Tumor

NCT03392064 2025-10-15

A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC

Phase 1 Suspended

Small Cell Lung Carcinoma

NCT04418167 2025-09-03

JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations

Phase 1 Suspended

DermatologicEndocrineHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Thyroid Carcinoma, Anaplastic

NCT05055518 2025-06-27

APL-102 Capsule in Patients With Advanced Solid Tumors

Phase 1 Suspended

Other solid neoplasm

Advanced Solid Tumor

NCT05958199 2025-06-27

A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7

Phase 1 Suspended

BreastGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Osteosarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT05191667 2025-02-13

AN0025 and Chemoradiotherapy Combination in Esophageal Cancer

Phase 1 Suspended

Gastrointestinal

Esophageal Neoplasms

NCT04120246 2024-07-10

Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer

Phase 1 Suspended

Breast Neoplasms, Neoplasm Metastasis

NCT04714983 2024-04-09

DNX-2440 for Resectable Colorectal Liver Metastasis

Phase 1 Suspended

BreastDermatologicGastrointestinalGenitourinarySarcoma

Breast Neoplasms, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Melanoma, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Gastrointestinal Stromal Tumors

NCT03932253 2024-03-27

MEK Inhibitor FCN-159 To Treat Advanced Melanoma With NRAS-aberrant (Ia) and NRAS-mutant (Ib)or NF1-mutant(1b)

Phase 1 Suspended

Melanoma

NCT04711161 2024-01-23

First-in-Human Evaluation of GRN-300 in Subjects With Recurrent Ovarian, Primary Peritoneal, and Fallopian Tube Cancers.

Phase 1 Suspended

Ovarian Neoplasms

NCT04996030 2024-01-23

A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia

Phase 1 Suspended

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT04053062 2024-01-05

LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer

Phase 1 Suspended

Castrate-Resistant Prostate Cancer

NCT03859752 2023-09-22

TR1801-ADC in Patients With Tumors That Express c-Met

Phase 1 Suspended

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT04650451 2023-04-20

Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors

Phase 1 Suspended

BreastGastrointestinal

Breast Neoplasms, Stomach Neoplasms

NCT03970382 2022-08-18

A Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid Tumors

Phase 1 Suspended

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Melanoma, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT03722186 2021-03-22

Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of SHR-1603 in Subjects With Advanced Malignancies

Phase 1 Suspended

LymphoidOther hematologic neoplasm

Lymphoma, Neoplasms by Histologic Type, Hematologic Neoplasms

NCT03120130 2019-10-14

Amblyomin-X

Phase 1 Suspended

Advanced Cancer

NCT02093871 2017-07-21

PISH-2

Phase 1 Suspended

Hyperthermia, Ovarian Neoplasms

NCT01762410 2014-09-29

Clinical Study of Oral PI3K/mTOR Inhibitor in Patients With Advanced Refractory Solid Tumors

Phase 1 Suspended

Other solid neoplasm

Advanced Refractory Solid Tumors

NCT01779336 2014-09-29

Clinical Study of Oral IGF-1R Inhibitor in Subjects With Advanced Refractory Solid Tumors

Phase 1 Suspended

Other solid neoplasm

Advanced Refractory Solid Tumors

NCT01841463 2014-09-04

Study of an Oral Cdk Inhibitor Administered With an Oral BRAF Inhibitor in Patients With Advanced or Inoperable Malignant Melanoma With BRAF Mutation

Phase 1 Suspended

Melanoma

NCT02117336 2014-09-03

Clinical Study of Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Phase 1 Suspended

LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

NCT01337518 2012-12-18

A Phase 1a/1b Study to Evaluate the Safety of EZN-4176, in Adult Patients With Castration-Resistant Prostate Cancer

Phase 1 Suspended

Adenocarcinoma, Neoplasm Metastasis, Prostatic Neoplasms, Bulbo-Spinal Atrophy, X-Linked

NCT01604863 2012-11-01

A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid Malignancies

Phase 1 Suspended

GenitourinaryOther solid neoplasmThoracic

Lung Neoplasms, Mesothelioma, Neoplasms, Prostatic Neoplasms, Small Cell Lung Carcinoma

NCT00909558 2010-02-24

Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on Cancer

Phase 1 Suspended

BreastCNSGastrointestinalGenitourinary

Breast Neoplasms, Colonic Neoplasms, Glioma, Liver Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT00459823 2009-03-24

A Dose Escalation Study of E7107 Administered IV (Bolus) on Days 1, 8, and 15 Every 28 Days to Patients With Solid Tumours

Phase 1 Suspended

Neoplasms

NCT00827203 2009-03-09

A Safety Study to Determine the Maximum Tolerated Dose of Elesclomol Sodium in Patients With Solid Tumors

Phase 1 Suspended

Neoplasm Metastasis, Neoplasms

NCT00499499 2009-02-04

A Dose Escalation Study of E7107 Administered Intravenously on Days 1 and 8 Every 21 Days to Patients With Solid Tumors

Phase 1 Suspended

Neoplasms

NCT00264472 2008-12-15

A Study of 5 Fluorouracil and the Anti-Tumor Activity of ADH300004 and 5 Fluorouracil in Subjects With Incurable Solid Tumors

Phase 1 Suspended

Neoplasms

NCT00753480 2008-11-07

A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 1 Suspended

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00460278 2008-06-04

Study of XL418 in Adults With Solid Tumors

Phase 1 Suspended

Neoplasms

NCT00607711 2008-05-05

Study of Oral Palifosfamide Tris in Solid Tumors

Phase 1 Suspended

Advanced Cancer

NCT00591682 2008-03-26

MSX-122 Administered Orally in Patients With Refractory Metastatic or Locally Advanced Solid Tumors

Phase 1 Suspended

Other solid neoplasm

Solid Tumors

NCT00077493 2007-12-28

BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma

Phase 1 Suspended

LymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating