Clinical Trials

GastrointestinalGynecologic

12 enrolled 18 charts

Adenocarcinoma, Peritoneal Neoplasms, Stomach Neoplasms

NCT03737994 2026-04-23

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

10 enrolled 17 charts

Thoracic

Lung Neoplasms

NCT04166383 2026-03-10

VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)

14 enrolled 13 charts

Colorectal Neoplasms

NCT05554354 2026-03-03

Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)

1 enrolled

Breast

Anatomic Stage IV Breast Cancer AJCC v8

NCT03785210 2026-02-23

Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers

22 enrolled 13 charts

Carcinoma, Hepatocellular, Liver Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03165721 2026-02-18

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

CNSEndocrineGastrointestinalGenitourinarySarcoma

9 enrolled 11 charts

Carcinoma, Renal Cell, Kidney Neoplasms, Paraganglioma, Pheochromocytoma, Gastrointestinal Stromal Tumors

NCT06865677 2026-01-21

Sacituzumab Govitecan for Relapsed Ovarian, Endometrial, and Cervical Carcinomas

2 enrolled 7 charts

Recurrence

NCT04616547 2025-10-03

Treatment of Cancer-Related Bone Pain by Using Bone-Targeted Radiation-Based Therapy (Sn-117m-DTPA) in Patients With Prostate Cancer That Has Spread to Bones

1 enrolled 8 charts

Prostatic Neoplasms

NCT05009979 2025-08-28

18F-DCFPyL PET/CT in Hepatocellular Carcinoma

8 enrolled 14 charts

Carcinoma, Hepatocellular, Liver Neoplasms

NCT04936230 2025-08-17

Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer

1 enrolled 1 chart

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT03018288 2025-08-08

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

90 enrolled 24 charts

CNS

Glioblastoma, Glioma

NCT04370834 2025-02-04

Tocilizumab for Patients With Cancer and COVID-19 Disease

Other hematologic neoplasm

1 enrolled 10 charts

Pneumonia, Respiratory Distress Syndrome, Hematologic Neoplasms

NCT04538378 2025-01-27

Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumors

4 enrolled 11 charts

EndocrineThoracic

EGFR-Mutated Non-Small-Cell Lung Carcinoma

NCT01413750 2024-11-12

Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancer

23 enrolled 10 charts

Stage IIIA Lung Non-Small Cell Cancer AJCC v7

NCT04027946 2024-04-16

LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

6 enrolled 14 charts

Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00019695 2024-03-04

Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate Cancer

Neoplasm Metastasis, Neoplasms, Prostatic Neoplasms, Genetic Diseases, Inborn

NCT02899728 2023-10-17

Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung Cancer

9 enrolled 4 charts

Extensive Stage Lung Small Cell Carcinoma

NCT03592641 2023-10-17

Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer

5 enrolled 8 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04566133 2023-08-21

Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).

2 enrolled 9 charts

Bile Duct Neoplasms, Biliary Tract Neoplasms, Cholangiocarcinoma

NCT02059265 2023-08-01

Dasatinib in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, Endometrial or Peritoneal Cancer

35 enrolled 13 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02917629 2023-03-08

ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment

6 enrolled 22 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT02408887 2022-09-27

Total Thyroidectomy With and Without Prophylactic Central Neck Lymph Node Dissection in People With Low-risk Papillary Thyroid Cancer

14 enrolled 14 charts

Head & Neck

Thyroid Neoplasms

NCT02572453 2022-09-13

Phase 2 Study of AT13387 (Onalespib) in ALK+ ALCL, MCL, and BCL-6+ DLBCL

25 enrolled 15 charts

Lymphoid

Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, Mantle-Cell

NCT02203513 2022-09-10

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

BreastGenitourinaryGynecologic

111 enrolled 15 charts

Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT03727841 2022-07-27

Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma

4 enrolled 13 charts

Ependymoma, Disease Progression

NCT03531827 2022-07-12

Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment

4 enrolled 12 charts

Prostatic Neoplasms

NCT04150562 2022-05-17

Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal Carcinoma

2 enrolled 13 charts

Carcinoma, Renal Cell

NCT03641326 2022-04-19

Sunitinib in Sarcomas of the Central Nervous System

5 enrolled 14 charts

CNSSarcoma

Brain Neoplasms, Gliosarcoma

NCT04501094 2022-03-22

A Phase II Study of Bintrafusp Alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects With Urothelial Carcinoma

2 enrolled 13 charts

Camurati-Engelmann Syndrome

NCT02362451 2022-03-18

Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men With Stage D0 Prostate Cancer

7 enrolled 10 charts

Prostatic Neoplasms

NCT04209621 2022-03-09

Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

LymphoidOther hematologic neoplasm

3 enrolled 12 charts

Leukemia, Lymphocytic, Chronic, B-Cell

NCT04015336 2022-02-24

E7 TCR Cell Induction Immunotherapy for Stage II and Stage III HPV-Associated Oropharyngeal Cancer

1 enrolled 6 charts

Head & Neck

Oropharyngeal Neoplasms, Papillomavirus Infections

NCT03050814 2021-12-20

Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

30 enrolled 15 charts

Turcot syndrome, Colorectal Neoplasms

NCT03644550 2021-12-02

Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma

Other solid neoplasmThoracic

18 enrolled 15 charts

Mesothelioma

NCT00001880 2021-11-10

Stem Cell Transplantation for Metastatic Solid Tumors

42 enrolled 11 charts

Graft vs Host Disease, Neoplasm Metastasis, Neoplasms

NCT03910439 2021-05-12

Avelumab in Combination With Hypofractionated Radiotherapy in Patients With Relapsed Refractory Multiple Myeloma

4 enrolled 12 charts

Plasma cell

Multiple Myeloma

NCT03937791 2021-04-13

Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

1 enrolled 8 charts

Neoplasms, Squamous Cell, Papillomavirus Infections

NCT03510455 2021-04-08

BGJ398 for the Treatment of Tumor-Induced Osteomalacia

4 enrolled 28 charts

Oncogenic osteomalacia, Hypophosphatemia

NCT00437034 2021-02-08

Aflibercept for Relapsed Multiple Myeloma

6 enrolled 5 charts

Plasma cell

Multiple Myeloma

NCT02315625 2020-09-09

Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery

16 enrolled 15 charts

EndocrineNET

Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT02326844 2020-08-18

BMN 673 (Talazoparib), an Oral PARP Inhibitor, in People With Deleterious BRCA1/2 Mutation-Associated Ovarian Cancer Who Have Had Prior PARP Inhibitor Treatment

3 enrolled 10 charts

Gynecologic

Ovarian Neoplasms

NCT02169284 2020-07-07

Erlotinib Hydrochloride in Treating Patients With Bladder Cancer Undergoing Surgery

50 enrolled 27 charts

Urinary Bladder Neoplasms

NCT01624090 2019-12-30

Mithramycin for Lung, Esophagus, and Other Chest Cancers

BreastGastrointestinalOther solid neoplasmThoracic

16 enrolled 13 charts

Breast Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Mesothelioma

NCT03300843 2019-12-13

Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer

BreastDermatologicGastrointestinalGynecologic

1 enrolled 7 charts

Breast Neoplasms, Gastrointestinal Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms

NCT01369875 2019-12-10

Modified Tumor Infiltrating Lymphocytes for Metastatic Melanoma

2 enrolled 8 charts

Dermatologic

Melanoma, Neoplasm Metastasis, Skin Neoplasms

NCT00924066 2019-11-21

Ixabepilone to Treat Cervical Cancer

41 enrolled 11 charts

Gynecologic

Uterine Cervical Neoplasms

NCT00117845 2019-11-19

Phase II Study of the Efficacy and Toxicity of Ontak(Registered Trademark) (Denileukin Diftitox) in the Therapy of Adult T-Cell Leukemia

LymphoidOther hematologic neoplasm

17 enrolled 9 charts

Lymphoproliferative Disorders, Leukemia-Lymphoma, Adult T-Cell

NCT00670748 2019-11-19

Chemotherapy Followed by ESO-1 Lymphocytes and Aldesleukin to Treat Metastatic Cancer

DermatologicGenitourinary

45 enrolled 15 charts

Carcinoma, Renal Cell, Melanoma, Neoplasm Metastasis

NCT01248455 2019-11-19

A Phase II Trial of Anti-KIR in Smoldering Multiple Myeloma