Clinical Trials

LymphoidOther hematologic neoplasm

533 enrolled 18 charts

Leukemia, Lymphocytic, Chronic, B-Cell

NCT02568267 2026-05-27

STARTRK-2

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

534 enrolled 1 FDA

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT04704934 2026-05-27

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

490 enrolled

Adenocarcinoma, Stomach Neoplasms

NCT04720157 2026-05-27

PSMAddition

1,140 enrolled

Phase 1/2 Active not recruiting

Prostatic Neoplasms

NCT04938817 2026-05-27

KEYNOTE-B98

110 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Small Cell Lung Carcinoma

NCT04958239 2026-05-27

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

151 enrolled

Tumor-Agnostic

Neoplasms

NCT05068102 2026-05-27

A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab

DermatologicHead & NeckThoracic

14 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05249426 2026-05-27

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

48 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05456191 2026-05-27

ASC4START

MyeloidOther hematologic neoplasm

568 enrolled 11 charts

Leukemia, Myeloproliferative Disorders, Philadelphia Chromosome, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT05849298 2026-05-27

PSMACare

49 enrolled

Prostatic Neoplasms

NCT05887011 2026-05-27

PASSAT

2,000 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06012435 2026-05-27

A Study of SGN-B6A Versus Docetaxel in Previously Treated Non-small Cell Lung Cancer

762 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms

NCT06077500 2026-05-27

DAREONᵀᴹ-8

46 enrolled

Small Cell Lung Carcinoma

NCT06120491 2026-05-27

EvoPAR-PR01

1,889 enrolled

Prostatic Neoplasms

NCT06225596 2026-05-27

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

375 enrolled

Urinary Bladder Neoplasms

NCT06346392 2026-05-27

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

592 enrolled

Stomach Neoplasms

NCT06459180 2026-05-27

TroFuse-020

686 enrolled

Gynecologic

Uterine Cervical Neoplasms

NCT06496568 2026-05-27

A Study Evaluating Single-agent Inavolisib, Inavolisib Plus Atezolizumab in PIK3CA-Mutated Cancers

30 enrolled

PIK3CA-Mutated Cancers

NCT06566547 2026-05-27

GR1803 Injection in Patients With Relapsed/Refractory Multiple Myeloma

116 enrolled

Plasma cell

Multiple Myeloma

NCT06619236 2026-05-27

RAINFOL-02

448 enrolled

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT06880549 2026-05-27

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

42 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence

NCT03875235 2026-05-26

TOPAZ-1

810 enrolled 24 charts 1 FDA

Biliary Tract Neoplasms

NCT04250155 2026-05-26

An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

195 enrolled

Other solid neoplasm

Solid Tumors

NCT04618913 2026-05-26

VICTORIE

1 enrolled

Classical hematology

Embolism, Neoplasms, Venous Thromboembolism

NCT04624204 2026-05-26

MK 7339-013

672 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Small Cell Lung Carcinoma

NCT05184088 2026-05-26

CArdiag

200 enrolled

Plasma cell

Immunoglobulin Light-chain Amyloidosis, Amyloid Neuropathies, Familial

NCT05445778 2026-05-26

GLORIOSA

Phase 1/2 Active not recruiting

520 enrolled

Gynecologic

Fallopian Tube Neoplasms, Neoplasms, Ovarian Neoplasms

NCT05593094 2026-05-26

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

210 enrolled

CNS

Brain Neoplasms

NCT05668988 2026-05-26

A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28)

324 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05723562 2026-05-26

AZUR-1

154 enrolled

Rectal Neoplasms

NCT05943106 2026-05-26

PATAPSCO

100 enrolled

Phase 1/2 Active not recruiting

Non-Muscle Invasive Bladder Neoplasms

NCT06188702 2026-05-26

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

60 enrolled

GastrointestinalThoracic

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT06533059 2026-05-26

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

BreastGenitourinaryGynecologic

110 enrolled

Breast Neoplasms, Uterine Cervical Neoplasms, Genital Neoplasms, Female, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

GastrointestinalGynecologicThoracic

750 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06612151 2026-05-26

A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer

438 enrolled

Small Cell Lung Carcinoma

NCT02632708 2026-05-22

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Other hematologic neoplasm

153 enrolled

Leukemia, Myeloid, Acute

NCT03311451 2026-05-22

C2 CryoBalloon™ 180 Ablation System Dose De-escalation Study.

Phase NA Active not recruiting

62 enrolled

Barrett Esophagus

NCT03941379 2026-05-22

A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma

63 enrolled

Dermatologic

Uveal Melanoma

NCT04277637 2026-05-22

Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies

Phase EARLY_PHASE1 Active not recruiting

437 enrolled

Lymphoid

Mature B-Cell Malignancies

NCT04541108 2026-05-22

Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

15 enrolled

DermatologicHead & NeckLymphoidSarcoma

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Lymphoma, Melanoma, Sarcoma

NCT04628494 2026-05-22

EPCORE DLBCL-1

483 enrolled

Lymphoid

Lymphoma, Large B-Cell, Diffuse

NCT04784715 2026-05-22

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

1,157 enrolled 1 FDA

Breast

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis

NCT04940052 2026-05-22

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer

153 enrolled 15 charts

EndocrineHead & Neck

Differentiated Thyroid Cancer (DTC)

NCT04961996 2026-05-22

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

4,170 enrolled

Breast

Breast Neoplasms

NCT04985643 2026-05-22

LEADER

357 enrolled

Plasma cell

Multiple Myeloma

NCT05043090 2026-05-22

SAMETA

148 enrolled

Carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis

NCT05109728 2026-05-22

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

65 enrolled

CNS

Glioblastoma

NCT05186753 2026-05-22

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

237 enrolled

Myeloid

Hematologic Diseases, Hypersensitivity, Immune Complex Diseases, Immune System Diseases, Mastocytosis, Mastocytosis, Systemic

NCT05208047 2026-05-22

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors