Clinical Trials

200 enrolled

CNS

Glioblastoma

NCT05237986 2026-04-16

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

LymphoidOther hematologic neoplasm

60 enrolled

Leukemia, Lymphoma

NCT05724121 2026-04-16

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

LymphoidOther hematologic neoplasm

135 enrolled

Arrhythmias, Cardiac, Atrial Fibrillation, Leukemia, Lymphocytic, Chronic, B-Cell, Death, Sudden, Cardiac, Hematologic Neoplasms, Lymphoma, Mantle-Cell

NCT06744283 2026-04-16

Experience and Management of Cancer Screening-Related Anxiety in Fanconi Anemia

20 enrolled

Classical hematology

Fanconi Anemia, Neoplasms

NCT07489378 2026-04-16

NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors

4,000 enrolled

Other solid neoplasm

Very Rare Tumors

NCT00092235 2026-04-15

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

650 enrolled

Chronic Graft vs. Host Disease

NCT01834001 2026-04-15

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

300 enrolled

Prostatic Neoplasms

NCT03952624 2026-04-15

Patient-Centered Assessment of Symptoms and Outcomes

692 enrolled

Fatigue, Neoplasms, Fatigue Syndrome, Chronic

NCT00001160 2026-04-14

Studies on Tumors of the Thyroid

2,500 enrolled

EndocrineHead & Neck

Thyroid cancer, Hurthle cell, Thyroid Cancer, Papillary, Thyroid Neoplasms, Adenocarcinoma, Follicular

NCT00001403 2026-04-14

Study of Proteus Syndrome and Related Congenital Disorders

1,500 enrolled

Abnormalities, Multiple, Growth Disorders, Proteus Syndrome

NCT00001532 2026-04-14

Role of Genetic Factors in the Development of Lung Disease

3,500 enrolled

Asthma, Cystic Fibrosis, Lung Diseases, Pulmonary Fibrosis, Tuberous Sclerosis, Sarcoidosis, Pulmonary, alpha 1-Antitrypsin Deficiency

NCT00001823 2026-04-14

Evaluation for NCI Surgery Branch Clinical Research Protocols

DermatologicGastrointestinalGenitourinaryThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Colorectal Neoplasms

NCT00006518 2026-04-14

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

1,029 enrolled

LymphoidSarcoma

Multi-centric Castleman's Disease, Acquired Immunodeficiency Syndrome, Lymphoma, Neoplasms, Sarcoma, Kaposi, Virus Diseases, Lymphoma, Primary Effusion

NCT00026650 2026-04-14

Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy

700 enrolled

Tumor-Agnostic

Neoplasms

NCT00026884 2026-04-14

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

5,950 enrolled

Urinary Bladder Neoplasms, Kidney Neoplasms, Neoplasms, Neoplastic Syndromes, Hereditary

NCT00027274 2026-04-14

Cancer in Inherited Bone Marrow Failure Syndromes

Classical hematologyDermatologic

4,000 enrolled

Congenital Bone Marrow Failure Syndromes, Shwachman-Diamond Syndrome, Anemia, Aplastic, Fanconi Anemia, Dyskeratosis Congenita, Anemia, Diamond-Blackfan

NCT00033137 2026-04-14

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

950 enrolled

Kidney Neoplasms, Neoplasms, Pneumothorax

NCT00034216 2026-04-14

Collection of Blood From Patients With Cancer

BreastGastrointestinalGenitourinaryThoracic

1,750 enrolled

Breast Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Prostatic Neoplasms

NCT00044122 2026-04-14

Study of Factors Regulating Mast Cell Proliferation

600 enrolled

Myeloid

Mastocytosis

NCT00050752 2026-04-14

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

1,130 enrolled

Kidney Neoplasms, Leiomyoma

NCT00060541 2026-04-14

Evaluation and Treatment of Neurosurgical Disorders

5,000 enrolled

CNSEndocrine

Brain Neoplasms, Epilepsy, Nervous System Diseases, Parkinson Disease, Pituitary Neoplasms, Spinal Cord Neoplasms

NCT00106925 2026-04-14

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

Plasma cell

Graft vs Host Disease, Neoplasms, Plasma Cell

NCT00598351 2026-04-14

Natural History Study of Patients With Neurofibromatosis Type 2

269 enrolled

CNS

Ependymoma, Meningioma, Neurilemmoma, Neuroma, Acoustic, Spinal Cord Neoplasms, Neurofibromatoses

NCT00867269 2026-04-14

Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

950 enrolled

Classical hematology

Autoimmune Diseases, Immunologic Deficiency Syndromes, Opportunistic Infections, Warts, Meningitis, Cryptococcal, T-Lymphocytopenia, Idiopathic CD4-Positive

NCT00900198 2026-04-14

Collection of Tissue Samples for Cancer Research

LymphoidMyeloidPlasma cell

5,000 enrolled

Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms

NCT00923221 2026-04-14

Collection of Blood From Patients With Prostate Cancer

Prostatic Neoplasms

NCT00923507 2026-04-14

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Waldenstrom Macroglobulinemia, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Marginal Zone

NCT01005654 2026-04-14

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

2,415 enrolled

CNSEndocrineHead & Neck

Adrenal Gland Neoplasms, Endocrine Gland Neoplasms, Neuroblastoma, Parathyroid Neoplasms, Thyroid Neoplasms

NCT01109394 2026-04-14

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

CNSGenitourinaryOther solid neoplasmSarcoma

6,035 enrolled

Kidney Neoplasms, Neoplasms, Neuroblastoma, Retinoblastoma, Sarcoma

NCT01143480 2026-04-14

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

725 enrolled

Asthma, Insulin Resistance, Neoplasms, Metabolic Syndrome, Atherosclerosis

NCT01441089 2026-04-14

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

BreastGenitourinaryGynecologicLymphoidThoracic

1,100 enrolled

Breast Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms

NCT02146170 2026-04-14

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

2,000 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT02595957 2026-04-14

Genomic Services Research Program

5,000 enrolled

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms

NCT02682667 2026-04-14

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

LymphoidOther hematologic neoplasmOther neoplasmPlasma cellThoracic

500 enrolled

Carcinoma, Non-Small-Cell Lung, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Precancerous Conditions, Leukemia-Lymphoma, Adult T-Cell

NCT03374215 2026-04-14

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

1,150 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Gland Neoplasms, Bone Diseases, Metabolic, Cardiovascular Diseases, Hyperaldosteronism, Hyperinsulinism, Hypertension

NCT04557969 2026-04-14

Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

400 enrolled

GastrointestinalSarcoma

Stomach Neoplasms, Gastrointestinal Stromal Tumors

NCT04706663 2026-04-14

Precision-Based Genomics in Prostate Cancer

2,000 enrolled

Prostatic Neoplasms, Genetic Predisposition to Disease

NCT05350761 2026-04-14

Rare Tumors and Cancer Predisposition in Individuals and Families

500 enrolled

Tumor-Agnostic

Neoplasms

NCT05588128 2026-04-14

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

350 enrolled

Prostatic Neoplasms

NCT00071045 2026-04-13

Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members

Other hematologic neoplasm

6,000 enrolled

Neoplasms, Hematologic Neoplasms

NCT01247597 2026-04-13

DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

1,500 enrolled

Head & Neck

Pleuropulmonary blastoma, Thyroid Neoplasms

NCT01905826 2026-04-13

Natural History Study of GATA2 Deficiency and Related Disorders

MyeloidOther hematologic neoplasm

600 enrolled

GATA2 Deficiency, Herpes Simplex, Leukemia, Myelodysplastic Syndromes

NCT05026138 2026-04-13

Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)

850 enrolled

Infections, Neoplasms

NCT05588154 2026-04-13

Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01950572 2026-04-09

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

GastrointestinalGynecologicOther solid neoplasmThoracic

Biliary Tract Neoplasms, Lung Neoplasms, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma

NCT04717349 2026-04-09

Data Collection Study of Pediatric and Adolescent Gynecology Conditions

11,000 enrolled

Congenital Abnormalities, Disorders of Sex Development

NCT04969926 2026-04-09

Natural History Study of Parathyroid Disorders

3,000 enrolled

EndocrineHead & Neck

Hyperparathyroidism, Parathyroid Neoplasms, Pseudohypoparathyroidism, Multiple Endocrine Neoplasia Type 1, Hyperparathyroidism, Primary

NCT06880991 2026-04-09

Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study

110 enrolled

CNS

Neurofibroma, Neurofibromatosis 1

NCT00032513 2026-04-08

Genetic Studies of Chronic Active Epstein-Barr Disease

300 enrolled

Lymphoid

Herpes Simplex, Infectious Mononucleosis, Lymphoproliferative Disorders, Virus Diseases, Epstein-Barr Virus Infections

NCT01087333 2026-04-08

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment