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Attention Deficit Disorder with Hyperactivity, Autistic Disorder, Brain Neoplasms, Cerebrovascular Disorders, Developmental Disabilities, Epilepsy, Intellectual Disability, Tic Disorders

NCT06462430 2025-12-04

PTEN Hamartoma Tumor Syndrome Pediatric Patient Registry

Recruiting

100 enrolled

Macrocephaly Autism Syndrome, Autistic Disorder, Hamartoma Syndrome, Multiple, Megalencephaly

NCT07218575 2025-10-20

Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

Phase 2/3 Not yet recruiting

60 enrolled

Autistic Disorder, Hamartoma Syndrome, Multiple

NCT06209463 2025-09-26

Posture, Hand Functions and Sensory Processing Skills on Nutrition

Completed

80 enrolled

Lymphoid

Autism Spectrum Disorder, Autistic Disorder, Lymphoma, Follicular

NCT04031469 2025-07-31

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Suspended

1,000 enrolled

GastrointestinalOtherOther solid neoplasmThoracic

Autism Spectrum Disorder, Bipolar and Related Disorders, Post-Lyme Disease Syndrome, Generalized Anxiety Disorder, Acne Vulgaris, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Anxiety Disorders, Arthritis, Rheumatoid, Autistic Disorder, Bipolar Disorder, Celiac Disease, Colitis, Ulcerative, Colonic Neoplasms, Compulsive Personality Disorder, Constipation, Crohn Disease, Depression, Depressive Disorder, Major, Diabetes Mellitus, Eczema, Epidermolysis Bullosa, Gout, Hypercholesterolemia, Lyme Disease, Mesothelioma, Migraine Disorders, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Obsessive-Compulsive Disorder, Parkinson Disease, Psoriasis, Colorectal Neoplasms, Fatigue Syndrome, Chronic, Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Relapsing-Remitting, Lyme Neuroborreliosis, Irritable Bowel Syndrome

NCT06081348 2025-07-16

CALM

Phase 2 Recruiting

130 enrolled

Autism Spectrum Disorder, Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Autistic Disorder, DiGeorge Syndrome, Fragile X Syndrome, Tourette Syndrome, Tic Disorders, Tuberous Sclerosis, 22q11 Deletion Syndrome, Neurodevelopmental Disorders

NCT02991807 2025-02-17

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

Phase 1/2 Completed

46 enrolled 15 charts

Autistic Disorder, Hamartoma Syndrome, Multiple, Intellectual Disability

NCT02461446 2024-10-26

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

Recruiting

170 enrolled

Autistic Disorder, Hamartoma Syndrome, Multiple, Megalencephaly

NCT02461459 2024-10-26

Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

Active not recruiting

205 enrolled

Autistic Disorder, Intellectual Disability, Tuberous Sclerosis

NCT05671107 2024-09-19

Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients

Completed

300 enrolled

Autistic Disorder, Hamartoma Syndrome, Multiple, Neurodevelopmental Disorders

NCT05635266 2024-05-07

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Recruiting

20,000 enrolled

Classical hematologyGenitourinaryHead & NeckLymphoidOther hematologic neoplasmPlasma cell

red meat allergy, Alopecia Areata, Alzheimer Disease, Amyloidosis, Anemia, Sickle Cell, Arthritis, Asthma, Autistic Disorder, Behcet Syndrome, Celiac Disease, Colitis, Ulcerative, Crohn Disease, Cystic Fibrosis, Dermatitis, Atopic, Diabetes Mellitus, Epilepsies, Myoclonic, Fibrosis, Fibromyalgia, Graves Disease, Heart Diseases, Hepatitis, Hypersensitivity, Kidney Diseases, Leukemia, Lupus Erythematosus, Systemic, Lymphoma, Macular Degeneration, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Parkinson Disease, Pemphigus, Psoriasis, Schizophrenia, Spondylitis, Ankylosing, Thyroid Diseases, Vasculitis, Vitiligo, beta-Thalassemia, Hidradenitis Suppurativa, Hepatitis, Autoimmune, Stroke, Pulmonary Disease, Chronic Obstructive, Scleroderma, Diffuse

NCT01431326 2023-09-06

PTN_POPS

Completed

3,520 enrolled

CNSClassical hematology

Healthcare-Associated Pneumonia, Pulmonary Arterial Hypertension, Schizophrenia, Treatment-Resistant, Adenoviridae Infections, Anxiety Disorders, Arrhythmias, Cardiac, Autistic Disorder, Bipolar Disorder, Bradycardia, Central Nervous System Infections, Endocarditis, Epilepsy, Headache, Heart Arrest, Heart Failure, Hemophilia A, Herpes Simplex, Hyperaldosteronism, Hypertension, Hypokalemia, Infections, Inflammation, Influenza, Human, Sleep Initiation and Maintenance Disorders, Meningitis, Menorrhagia, Migraine Disorders, Neutropenia, Pain, Pneumonia, Retinitis, Schizophrenia, Seizures, Spasm, Staphylococcal Infections, Urinary Tract Infections, Meningitis, Bacterial, Cytomegalovirus Retinitis, Hemangioma, Capillary, Sepsis, Renal Insufficiency, Chronic, Intraabdominal Infections

NCT03944447 2022-06-02

OMNI-Can

Phase 2 Unknown

200,000 enrolled

Classical hematology

Chronic Traumatic Encephalopathy, Brain Injuries, Traumatic, COVID-19, Acquired Immunodeficiency Syndrome, Amyotrophic Lateral Sclerosis, Anemia, Sickle Cell, Anxiety Disorders, Autistic Disorder, Bipolar Disorder, Colitis, Ulcerative, Crohn Disease, Depression, Epilepsy, Fibromyalgia, Tourette Syndrome, Glaucoma, Hepatitis C, Sleep Initiation and Maintenance Disorders, Multiple Sclerosis, Opioid-Related Disorders, Neoplasms, Parkinson Disease, Seizures, Stress Disorders, Post-Traumatic, Inflammatory Bowel Diseases, Coronavirus Infections, Severe Acute Respiratory Syndrome, Chronic Pain

NCT01929642 2021-03-29