Clinical Trials

Bone Neoplasms

NCT01896505 2024-01-08

A Phase I Trial to Assess the Effects of Food and Formulation on PK of KPT-330 in Patients With Sarcoma

Phase 1 Completed

54 enrolled 28 charts

Bone Neoplasms, Sarcoma

NCT01336803 2023-12-27

Osteosarcoma

32 enrolled 11 charts

GastrointestinalHead & NeckSarcoma

Bone Neoplasms, Chondrosarcoma, Osteomyelitis, Osteonecrosis, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT03525392 2023-12-12

Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.

Phase 1 Terminated

14 enrolled 20 charts

Squamous Cell Carcinoma of Head and Neck, Bone Neoplasms, Neoplasm Metastasis, Recurrence, Stomach Neoplasms, Colorectal Neoplasms

NCT04788147 2023-10-31

BIOGUIDE-X

30 enrolled 17 charts

SarcomaThoracic

Bone Neoplasms, Lung Neoplasms, Neoplasms

NCT02500797 2023-10-17

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

164 enrolled 22 charts

Other hematologic neoplasmPlasma cellSarcoma

Bone Neoplasms, Liposarcoma, Sarcoma, Histiocytoma, Malignant Fibrous

NCT01345019 2022-11-08

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Phase 3 Completed

1,718 enrolled 22 charts

Blood Protein Disorders, Bone Diseases, Bone Marrow Diseases, Bone Neoplasms, Hematologic Diseases, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Paraproteinemias, Spinal Cord Compression, Hematologic Neoplasms, Fractures, Bone, Neoplasms, Plasma Cell

NCT03072186 2021-04-26

ICG2

23 enrolled 5 charts

Bone Diseases, Bone Neoplasms, Musculoskeletal Diseases, Neoplasms, Skull Neoplasms, Skull Base Neoplasms

NCT00525057 2021-01-22

Dalteparin in Preventing DVT in Participants With Cancer

LymphoidPlasma cellSarcoma

65 enrolled 14 charts

Bone Neoplasms, Femoral Fractures, Fractures, Spontaneous, Lymphoma, Multiple Myeloma, Neoplasm Metastasis, Sarcoma

NCT00381095 2021-01-20

COPE

Phase 4 Terminated

152 enrolled 14 charts

Bone Neoplasms, Neoplasms, Pain, Intractable

NCT03468075 2020-12-10

Gemcitabine Plus Ascorbate for Sarcoma in Adults

Phase 2 Terminated

10 enrolled 13 charts

Bone Neoplasms, Sarcoma

NCT02301039 2020-09-29

SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas

144 enrolled 16 charts

Bone Neoplasms, Sarcoma

NCT03204942 2020-07-07

Dorsal Root Ganglion Thermal Radiofrequency Versus Pulsed Radiofrequency for Metastatic Pain in Thoracic Vertebral Body

69 enrolled 16 charts

BreastGenitourinarySarcomaThoracic

Cancer Pain, Bone Neoplasms

NCT00981578 2020-03-11

ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain

Phase NA Terminated

37 enrolled 10 charts

Cancer Pain, Bone Neoplasms, Breast Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Prostatic Neoplasms

NCT00656305 2020-02-05

ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain

BreastGenitourinaryPlasma cellSarcomaThoracic

147 enrolled 12 charts

Cancer Pain, Bone Neoplasms, Breast Neoplasms, Lung Neoplasms, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Prostatic Neoplasms

NCT01185639 2019-11-29

Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung Cancer

EndocrineGastrointestinalSarcomaThoracic

29 enrolled 8 charts

Adrenal Gland Neoplasms, Bone Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT01886105 2019-10-29

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma

Phase 2 Terminated

4 enrolled 9 charts

Bone Neoplasms, Sarcoma, Osteosarcoma

NCT00960063 2018-08-27

A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006)

Phase 1 Terminated

4 enrolled 8 charts

CNSGenitourinarySarcoma

Bone Neoplasms, Carcinoma, Renal Cell, Neoplasms, Neuroblastoma

NCT01553539 2018-07-05

Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery

20 enrolled 10 charts

Bone Neoplasms, Chondrosarcoma, Sarcoma, Osteosarcoma

NCT01610570 2018-03-02

Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma

Phase 1/2 Terminated

8 enrolled 20 charts

Bone Neoplasms, Sarcoma, Sarcoma, Ewing

NCT02443103 2018-02-13

Study Evaluating the Biologic Activity of Guanabenz in Bone Metastasis

Phase NA Terminated

4 enrolled 7 charts

Bone Neoplasms, Neoplasm Metastasis

NCT01313884 2017-11-24

Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma

Phase 2 Terminated

3 enrolled 7 charts

Bone Neoplasms, Sarcoma, Ewing

NCT03002454 2017-10-03

Sodium Pertechnetate (99Tc) Injection Generator: 99mTc From Neutron-activation 99Mo v 99mTc From Fission 99Mo

Phase 3 Terminated

4 enrolled 5 charts

Bone Neoplasms

NCT01541358 2017-06-14

Sodium Fluoride PET/CT for the Evaluation of Skeletal Cancer

Phase NA Terminated

2 enrolled 8 charts

Bone Neoplasms

NCT00474994 2016-01-20

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

53 enrolled 6 charts

GynecologicSarcoma

Malignant mesenchymal tumor, AIDS-related Kaposi sarcoma, Hemangiopericytoma, Malignant, Chondrosarcoma, Extraskeletal Myxoid, Bone Neoplasms, Chondrosarcoma, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Ovarian Neoplasms, Rhabdomyosarcoma, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Sarcoma, Synovial, Endometrial Neoplasms, Sarcoma, Endometrial Stromal, Desmoid Tumors, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Neuroectodermal Tumors, Primitive, Peripheral, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT01132547 2015-07-02

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Phase 3 Terminated

22 enrolled 9 charts

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Body Weight Changes, Bone Neoplasms, Cachexia, Chondrosarcoma, Fibrosarcoma, Glioblastoma, Hemangiosarcoma, Liposarcoma, Medulloblastoma, Nausea, Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Sarcoma, Sarcoma, Ewing, Mast-Cell Sarcoma, Osteosarcoma, Testicular Neoplasms, Vomiting, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Hepatoblastoma, Sarcoma, Endometrial Stromal, Neuroectodermal Tumors, Primitive, Peripheral, Neoplasms, Neuroepithelial, Optic Nerve Glioma

NCT00558272 2013-05-27

Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic Bone Disease