Clinical Trials

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT05327023 2026-04-28

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Phase 1/2 Recruiting

430 enrolled

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT06427811 2026-04-17

ASC4INDIA

Phase 4 Completed

85 enrolled

Phase 2 Active not recruiting

Bronchiolitis Obliterans Syndrome, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT04710576 2026-03-16

AGAVE-201

241 enrolled 11 charts 1 FDA

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease

NCT04294641 2026-01-23

Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease

10 enrolled 15 charts

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT04063215 2026-01-15

A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy

24 enrolled 67 charts

Lymphoid

Brain Injuries, Traumatic, Bronchiolitis Obliterans Syndrome, Cerebral Palsy, Lymphoma, Follicular, Trauma, Nervous System, Intracranial Hemorrhages, Stroke, Hypoxia-Ischemia, Brain

NCT03774082 2025-12-11

REACH 5

46 enrolled 21 charts

Lymphoid

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease, Lymphoma, Follicular

NCT06075836 2025-11-24

AID-CXR

Completed

33 enrolled

Thoracic

Bronchiolitis Obliterans Syndrome, Pulmonary Atelectasis, Solitary Pulmonary Nodule, Cardiomegaly, Pleural Effusion, Pneumoperitoneum, Pneumothorax, Pulmonary Fibrosis, Multiple Pulmonary Nodules

NCT03790332 2025-10-21

Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)

59 enrolled 1 FDA

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease

NCT07200882 2025-10-01

What is the Impact of TKI on Thyroid Function in CML Patients?

Not yet recruiting

76 enrolled

330 enrolled 32 charts 1 FDA

Bronchiolitis Obliterans Syndrome, Leukemia

NCT05951777 2025-09-29

Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury

Phase 2 Recruiting

51 enrolled

Lymphoid

Brain Injuries, Traumatic, Bronchiolitis Obliterans Syndrome, Lymphoma, Follicular, Trauma, Nervous System, Intracranial Hemorrhages

NCT03112603 2025-08-12

A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

Phase 3 Completed

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease

NCT07079150 2025-07-22

Real-world Study Evaluating the Long-term Outcomes of Pegylated Interferon α-2b Treatment in the Families With Clusters of HBV Infection and Unfavorable Prognosis - A Prospective, Controlled, Multicenter, Cohort Study

Recruiting

1,500 enrolled

Gastrointestinal

Bronchiolitis Obliterans Syndrome, Fibrosis, Hepatitis B, Carcinoma, Hepatocellular

NCT04795427 2025-04-18

Study of Efficacy and Safety of CML-CP Patients Treated With Asciminib Versus Best Available Therapy, Previously Treated With 2 or More Tyrosine Kinase Inhibitors

84 enrolled

LymphoidMyeloidOther hematologic neoplasm

Bronchiolitis Obliterans Syndrome, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT06462365 2025-04-15

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

Phase 1 Recruiting

36 enrolled

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT02743546 2025-02-03

Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Duvortuxizumab (JNJ-64052781) Plus Ibrutinib in Lymphoma

Phase 1 Withdrawn

Bronchiolitis Obliterans Syndrome, Lymphoma, Follicular, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT02388048 2025-01-29

Ofatumumab & Ibrutinib + Allogeneic Bone Marrow Transplant or Consolidation in High Risk Chronic Lymphocytic Leukemia

19 enrolled

Bronchiolitis Obliterans Syndrome, Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT04716075 2025-01-16

ACALLO

29 enrolled

159 enrolled 25 charts 1 FDA

Bronchiolitis Obliterans Syndrome, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Neoplasm, Residual, Lymphoma, Mantle-Cell

NCT03640481 2024-12-12

Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy

Phase 2 Terminated

Bronchiolitis Obliterans Syndrome

NCT00457782 2024-04-25

A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma

Phase 1 Completed

27 enrolled

LymphoidOther hematologic neoplasmPlasma cell

Bronchiolitis Obliterans Syndrome, Hematologic Diseases, Leukemia, Lymphoma, Multiple Myeloma, Neoplasms, Leukemia, B-Cell, Lymphoma, B-Cell

NCT01063907 2024-04-25

A Study of KW-2478 in Combination With Bortezomib in Subjects With Relapsed and/or Refractory Multiple Myeloma

LymphoidOther hematologic neoplasmPlasma cell

95 enrolled 13 charts

Bronchiolitis Obliterans Syndrome, Blood Protein Disorders, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Paraproteinemias, Leukemia, B-Cell, Neoplasms, Plasma Cell

NCT05963061 2024-04-09

Chronic Myeloid Leukemia (CML) Real-Life Database

Recruiting

3,500 enrolled

Bronchiolitis Obliterans Syndrome, Leukemia, Leukemia, Myeloid, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematologic Neoplasms

NCT06335277 2024-03-28

Total Body Irradiation Treatments for Patients Treated at European Institute of Oncology

Classical hematologyLymphoidOther hematologic neoplasm

50 enrolled

Bronchiolitis Obliterans Syndrome, Anemia, Aplastic, Leukemia, Lymphoma

NCT06279585 2024-02-28

Physical Therapy in Patients Undergoing Allo-HSCT With cGVHD

Phase NA Unknown

108 enrolled

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease, Motor Activity, Hematologic Neoplasms

NCT05692713 2023-12-08

Polyomic Biomarker Verification in Adult Chronic Graft-Versus-Host Disease (ABLE3.0/CTTC2201)

320 enrolled

Bronchiolitis Obliterans Syndrome, Leukemia, Hematologic Neoplasms

NCT04372524 2023-12-05

Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study

350 enrolled

Bronchiolitis Obliterans Syndrome, Leukemia, Hematologic Neoplasms

NCT04884204 2023-11-28

SIMPly-CARE

Phase NA Completed

35 enrolled

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT03557749 2023-08-21

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Terminated

210 enrolled

Cytokine Release Syndrome, Bronchiolitis Obliterans Syndrome, Neoplasms

NCT02743351 2023-02-08

Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies

LymphoidMyeloidOther hematologic neoplasm

96 enrolled 13 charts

Bronchiolitis Obliterans Syndrome, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05413356 2022-10-19

Ruxolitinib for Newly Diagnosed Bronchiolitis Obliterans Syndrome

Phase 2 Unknown

50 enrolled

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT05355675 2022-08-02

The Association of Microbiota Composition With cGVHD After Allo-HSCT

300 enrolled

Bronchiolitis Obliterans Syndrome, Hematologic Neoplasms

NCT01991184 2022-06-21

A Study of GDC-0853 in Patients With Resistant B-Cell Lymphoma or Chronic Lymphocytic Leukemia.

Phase 1 Completed

24 enrolled

Bronchiolitis Obliterans Syndrome, Leukemia, Lymphoid, Lymphoma, Large B-Cell, Diffuse

NCT01994382 2022-04-05

Phase 1/2a Dose Escalation Study in Participants With CLL, SLL, or NHL

DermatologicLymphoidOther hematologic neoplasm

260 enrolled 33 charts

Bronchiolitis Obliterans Syndrome, Leukemia, Lymphoma, Follicular, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT03759184 2022-03-22

Human IL-15 (rhIL-15) and Obinutuzumab for Relapsed and Refractory Chronic Lymphocyte Leukemia

Phase 1 Terminated

1 enrolled 13 charts

Bronchiolitis Obliterans Syndrome, Leukemia

NCT03251352 2022-03-16

TFR_china

98 enrolled

Bronchiolitis Obliterans Syndrome, Leukemia

NCT02228382 2021-12-30

Safety And Efficacy Study Of Bosutinib In Patients With Philadelphia Chromosome Positive Chronic Myeloid Leukemia Previously Treated With One Or More Tyrosine Kinase Inhibitors

Phase 4 Terminated

163 enrolled 27 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Bronchiolitis Obliterans Syndrome, Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT01663766 2021-08-19

Phase I Study of Milatuzumab for Graft Versus Host Disease

Phase 1 Terminated

12 enrolled

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04118075 2021-05-21

PT-CY With or Without Low-dose ATG for Lymphoid Malignancies Undergoing Allo-HSCT

536 enrolled 24 charts 1 FDA

23 enrolled

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease

NCT02130557 2021-05-18

A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

Phase 3 Completed

Bronchiolitis Obliterans Syndrome, Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Myeloid, Neoplasms by Histologic Type, Pathologic Processes, Philadelphia Chromosome, Translocation, Genetic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT01844765 2021-04-22

DIALOG

59 enrolled 33 charts 1 FDA

Bronchiolitis Obliterans Syndrome, Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myeloproliferative Disorders, Neoplastic Processes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT03672422 2020-11-06

INSPPIRE 2

Completed

623 enrolled

Bronchiolitis Obliterans Syndrome, Pancreatitis, Recurrence, Pancreatitis, Chronic

NCT02638467 2020-11-05

Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs Therapy

2 enrolled