Clinical Trials Browser

Fibroma, Desmoid Tumors

NCT06268457 2026-05-14

Embodesmo

Recruiting

20 enrolled

Sarcoma

Desmoid Tumors

NCT06660121 2026-05-14

ECT-DESMO

Withdrawn

Sarcoma

Desmoid Tumors

NCT02834013 2026-05-13

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Phase 2 Active not recruiting

818 enrolled

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

Nasopharyngeal Carcinoma, Bile Duct Neoplasms, Carcinoma, Basal Cell, Adenocarcinoma, Bronchiolo-Alveolar, Adenocarcinoma, Mucinous, Carcinoma, Transitional Cell, Carcinosarcoma, Chordoma, Carcinoma, Adenoid Cystic, Fibroma, Gallbladder Neoplasms, Hemangiosarcoma, Mouth Neoplasms, Paget Disease, Extramammary, Paraganglioma, Paranasal Sinus Neoplasms, Parathyroid Neoplasms, Pheochromocytoma, Pseudomyxoma Peritonei, Somatostatinoma, Thyroid Neoplasms, Vulvar Neoplasms, Desmoid Tumors, Seminoma, Carcinoma, Acinar Cell, Adrenocortical Carcinoma, Carcinoma, Endometrioid, Cholangiocarcinoma, Cystadenocarcinoma, Mucinous, Cystadenocarcinoma, Serous, Carcinoma, Giant Cell, Neurofibrosarcoma, Gestational Trophoblastic Disease, Rare Diseases, Gastrointestinal Stromal Tumors, Perivascular Epithelioid Cell Neoplasms

NCT05919264 2026-05-12

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Phase 1/2 Recruiting

595 enrolled

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Craniopharyngioma, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT06224283 2026-05-12

Cryomics

Recruiting

21 enrolled

Sarcoma

Desmoid Tumors

NCT05041036 2026-05-08

Individual Patient Compassionate Use of Nirogacestat

Available

Sarcoma

Desmoid Tumors

NCT07170644 2026-05-08

A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

Phase 2 Active not recruiting

20 enrolled

Sarcoma

Desmoid Tumors

NCT07176689 2026-05-08

Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

Phase 4 Recruiting

50 enrolled

Sarcoma

Desmoid Tumors

NCT02402244 2026-05-05

Project: Every Child for Younger Patients With Cancer

Recruiting

75,000 enrolled

CNSDermatologicEndocrineLymphoidMyeloidNETSarcoma

Carcinoma in Situ, Ganglioneuroma, Lymphoproliferative Disorders, Melanoma, Myeloproliferative Disorders, Neoplasms, Pheochromocytoma, Central Nervous System Neoplasms, Nephroma, Mesoblastic, Desmoid Tumors, Neuroendocrine Tumors

NCT04851119 2026-05-05

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Phase 1/2 Recruiting

147 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Carcinoma, Hepatocellular, Lymphoma, Non-Hodgkin, Melanoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Ewing, Osteosarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Hepatoblastoma, Desmoid Tumors

NCT07541430 2026-04-30

A Study in Adults With Desmoid Tumors

Phase 2 Recruiting

50 enrolled

Sarcoma

Desmoid Tumors

NCT06502483 2026-04-21

PRISM

Phase NA Completed

13 enrolled

Sarcoma

Anxiety Disorders, Depression, Depressive Disorder, Desmoid Tumors

NCT04195399 2026-04-15

A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery

Phase 2 Active not recruiting

31 enrolled

Sarcoma

Desmoid Tumors

NCT02867033 2026-03-30

ALTITUDES

Phase NA Active not recruiting

628 enrolled

Sarcoma

Desmoid Tumors

NCT07496242 2026-03-27

Immunological Phenotype of Desmoid-fibromatosis-affected Patients.

Recruiting

200 enrolled

Sarcoma

Desmoid Tumors

NCT01046487 2026-03-13

PALANGI3

Phase 1 Completed

26 enrolled

DermatologicGastrointestinalSarcoma

Uveal Melanoma, Chordoma, Carcinoma, Adenoid Cystic, Neoplasms, Desmoid Tumors, Dermatofibrosarcoma, Gastrointestinal Stromal Tumors

NCT07461246 2026-03-10

RIPAF

Active not recruiting

1,500 enrolled

GastrointestinalSarcoma

Turcot syndrome, Attenuated familial adenomatous polyposis, Polyposis Syndrome, Hereditary Mixed, 1, Gardner Syndrome, Neoplastic Syndromes, Hereditary, Adenomatous Polyposis Coli, Colorectal Neoplasms, Desmoid Tumors

NCT03833700 2026-02-27

A Study of E7386 in Participants With Advanced Solid Tumor Including Colorectal Cancer (CRC)

Phase 1 Active not recruiting

70 enrolled

EndocrineGastrointestinalNETSarcoma

Gastro-enteropancreatic neuroendocrine tumor, Digestive System Neoplasms, Carcinoma, Hepatocellular, Colorectal Neoplasms, Desmoid Tumors, Adrenocortical Carcinoma

NCT04871282 2026-02-05

RINGSIDE

Phase 2/3 Active not recruiting

198 enrolled

Sarcoma

Desmoid Tumors

NCT05111964 2026-02-04

SarcAblate

Phase NA Recruiting

10 enrolled

Sarcoma

Sarcoma, Desmoid Tumors

NCT02476305 2026-01-20

CRYODESMO01

Phase NA Completed

50 enrolled

Sarcoma

Desmoid Tumors

NCT01273168 2025-12-23

Endoxifen in Adults With Hormone Receptor Positive Solid Tumors

Phase 1 Completed

40 enrolled

BreastGynecologicSarcoma

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT06081400 2025-11-19

CRYODESMO-02

Phase NA Recruiting

150 enrolled

Sarcoma

Desmoid Tumors

NCT06945887 2025-09-12

TAE-DESMO

Recruiting

20 enrolled

Sarcoma

Desmoid Tumors

NCT02547831 2025-09-11

Tailored Beta-catenin Mutational Approach in Extra-abdominal Sporadic Desmoids Tumor Patients

Completed

100 enrolled

Sarcoma

Desmoid Tumors

NCT05949099 2025-09-08

Study of Cryoablation and Nirogacestat for Desmoid Tumor

Phase 2 Recruiting

28 enrolled

Sarcoma

Desmoid Tumors

NCT06258421 2025-08-24

PROSa Desmoid

Completed

100 enrolled

Sarcoma

Desmoid Tumors

NCT05091255 2025-08-01

Cryotherapy in the Treatment of Desmoid Tumors

Phase NA Recruiting

94 enrolled

Sarcoma

Desmoid Tumors

NCT02228889 2025-06-06

RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction

Phase NA Completed

46 enrolled 7 charts

GynecologicSarcoma

Hernia, Hernia, Ventral, Intestinal Fistula, Peritoneal Neoplasms, Fibromatosis, Abdominal, Desmoid Tumors

NCT03190174 2025-02-17

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

Phase 1/2 Completed

34 enrolled 14 charts

DermatologicGastrointestinalGenitourinarySarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Chordoma, Carcinoma, Hepatocellular, Melanoma, Sarcoma, Sarcoma, Ewing, Colorectal Neoplasms, Desmoid Tumors, Perivascular Epithelioid Cell Neoplasms

NCT03785964 2025-01-31

DeFi

Phase 3 Completed

142 enrolled 21 charts 1 FDA

Sarcoma

Desmoid Tumors

NCT02076906 2025-01-01

MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

Phase 1 Completed

7 enrolled

CNSGastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoid Tumors

NCT03802084 2024-05-13