Clinical Trials Browser

Fibrosis × Clear all

NCT03520660 2026-05-22

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Phase 4 Active not recruiting

Gastrointestinal

Cardiovascular Diseases, Diabetes Mellitus, Fibrosis, Hepatitis C, Carcinoma, Hepatocellular, Hepatitis C, Chronic

NCT01082419 2026-05-14

NARFI

Phase NA Completed

Gastrointestinal

Digestive System Diseases, Fibrosis, Heart Failure, Carcinoma, Hepatocellular, Liver Cirrhosis

NCT05027425 2026-05-06

Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant

Phase 2 Terminated

8 enrolled 9 charts

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Hypertension, Portal

NCT02908048 2026-05-05

Extracellular RNA Markers of Liver Disease and Cancer

Gastrointestinal

Bile Duct Neoplasms, Biliary Tract Neoplasms, Fibrosis, Hepatitis, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Cholangiocarcinoma

NCT02968810 2026-05-04

Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis

Phase 2 Active not recruiting

52 enrolled 15 charts

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT06096779 2026-05-04

Kirros

Phase 2 Recruiting

Gastrointestinal

Digestive System Neoplasms, Fatty Liver, Fibrosis, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms

NCT02626312 2026-04-30

Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function

Phase 1 Active not recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT05637216 2026-04-24

Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients

Phase 2 Recruiting

Radiation Fibrosis Syndrome, Breast Neoplasms, Camurati-Engelmann Syndrome, Fibrosis, Inflammation

NCT03612531 2026-04-23

MANTLE

Phase NA Active not recruiting

Deglutition Disorders, Fibrosis

NCT05486572 2026-04-21

PREMIUM

Phase NA Recruiting

Gastrointestinal

Chronic Disease, Fibrosis, Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasms

NCT07529262 2026-04-14

AspiRe HCC

Phase 3 Not yet recruiting

Carcinoma, Fibrosis, Liver Cirrhosis, Neoplasms

NCT05263362 2026-04-13

STARLINGS

Breast Carcinoma In Situ, Breast Neoplasms, Fibrosis

NCT05874492 2026-04-13

FIBROTHERME

Phase NA Recruiting

BreastHead & Neck

Breast Neoplasms, Fibrosis, Head and Neck Neoplasms

NCT04620538 2026-03-30

VOCAL

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Liver Cirrhosis, Liver Neoplasms

NCT05586516 2026-03-30

A Study to Assess an ATX Inhibitor (IOA-289) in Patients With Metastatic Pancreatic Cancer

Phase 1/2 Completed

Gastrointestinal

Fibrosis, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT07469319 2026-03-13

BISHOP

Phase NA Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT05095714 2026-03-12

FASTRAK

Phase NA Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Liver Neoplasms

NCT07010315 2026-03-04

Development and Testing of a Patient-facing Educational Tool About Liver Cancer Prevention

Gastrointestinal

Fibrosis, Liver Diseases, Liver Neoplasms

NCT04485286 2026-02-27

Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury

Phase 2 Recruiting

GastrointestinalThoracic

Radiation Fibrosis Syndrome, Fibrosis, Lung Neoplasms, Pancreatic Neoplasms

NCT06624189 2026-02-27

Active Choice Clinical Decision Support (CDS): Hepatocellular Carcinoma (HCC) Screening in Patients With Cirrhosis

Enrolling by invitation

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT06458998 2026-02-23

GTI

Phase NA Enrolling by invitation

30,300 enrolled

Gastrointestinal

Colonic Neoplasms, Fibrosis, Liver Neoplasms

NCT04690972 2026-02-12

LivMOD

Gastrointestinal

Hepatitis D, Fibrosis, Hepatitis B, Hepatitis C, Liver Diseases, Liver Neoplasms, Non-alcoholic Fatty Liver Disease

NCT06061328 2026-02-04

OASIS

Phase NA Enrolling by invitation

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Liver Neoplasms

NCT06912763 2026-01-26

Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)

Phase 2 Recruiting

Fibrosis, Head and Neck Neoplasms, Lymphedema

NCT07368309 2026-01-26

Clinical Management Strategies for Patients With Cirrhosis and Esophagogastric Varices Complicated by Early-stage Upper Gastrointestinal Cancer

Gastrointestinal

Fibrosis, Gastrointestinal Neoplasms

NCT03654053 2026-01-07

SACRED

Phase 3 Active not recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT04306939 2026-01-07

GREAT1

120,000 enrolled

Gastrointestinal

Arthritis, Rheumatoid, Celiac Disease, Cholecystitis, Cholelithiasis, Chronic Disease, Crohn Disease, Cystic Fibrosis, Diabetes Mellitus, Fibrosis, Gastritis, Hepatitis, Liver Cirrhosis, Biliary, Multiple Sclerosis, Pancreatic Cyst, Exocrine Pancreatic Insufficiency, Pancreatitis, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Dyslipidemias, Pancreatitis, Chronic, Renal Insufficiency, Chronic, Chronic Pain, Non-alcoholic Fatty Liver Disease

NCT00243633 2025-12-23

Characterization of Focal Liver Lesions by Real-time Contrast-enhanced Ultrasound Imaging (CEUS)

Phase NA Completed

Gastrointestinal

Fibrosis, Liver Cirrhosis, Liver Neoplasms

NCT03071458 2025-12-10

MUTHEC

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT05064553 2025-10-15

ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

Active not recruiting

Gastrointestinal

Fibrosis, Hepatitis B, Carcinoma, Hepatocellular, Liver Neoplasms

NCT06007846 2025-09-30

A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer

Phase 2/3 Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT06265272 2025-09-26

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Hypertension, Portal, Liver Cirrhosis

NCT05971108 2025-09-24

REVISE-HCC

Phase NA Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Liver Cirrhosis

NCT06658782 2025-09-22

AMULET

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT07185360 2025-09-22

LIVER-TRACK

Phase NA Not yet recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Liver Diseases, Hepatic Insufficiency

NCT07149506 2025-09-08

OCTOPUS-RD

Phase 3 Enrolling by invitation

Fibrosis, Radiodermatitis

NCT07132515 2025-08-20

Efficacy & Safety of Anticoagulants in Cirrhosis ± HCC

Phase 4 Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT06125743 2025-08-14

Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]

Phase NA Recruiting

Fibrosis, Head and Neck Neoplasms, Lymphedema

NCT05433467 2025-08-13

CTMH

Phase NA Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Liver Cirrhosis

NCT05463796 2025-08-07

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

GastrointestinalGynecologicOther hematologic neoplasmThoracic

Barrett Esophagus, Carcinoma in Situ, Endometrial Hyperplasia, Fibrosis, Giant Cell Tumors, Lung Neoplasms, Osteochondroma, Carcinoma, Lobular, Nevus, Epithelioid and Spindle Cell, Hematologic Neoplasms, Non-alcoholic Fatty Liver Disease

NCT07079150 2025-07-22

Real-world Study Evaluating the Long-term Outcomes of Pegylated Interferon α-2b Treatment in the Families With Clusters of HBV Infection and Unfavorable Prognosis - A Prospective, Controlled, Multicenter, Cohort Study

Gastrointestinal

Bronchiolitis Obliterans Syndrome, Fibrosis, Hepatitis B, Carcinoma, Hepatocellular

NCT07036874 2025-06-29

Non-invasive Assessment for Outcome Prediction in Patients With Hepatocellular Carcinoma

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT07042919 2025-06-29

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

Phase 1/2 Not yet recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT05339984 2025-06-27

LSM

Phase NA Recruiting

Fibrosis, Hypertension, Portal, Liver Diseases

NCT03534141 2025-05-16

MHALT

Phase NA Terminated

175 enrolled 19 charts

GastrointestinalGenitourinary

Fibrosis, Hepatitis B, Hepatitis C, Carcinoma, Hepatocellular, Hypothermia, Liver Cirrhosis, Alcoholic, Renal Insufficiency, Chronic, Acute Kidney Injury, End Stage Liver Disease, Non-alcoholic Fatty Liver Disease

NCT05178303 2025-05-16

SB-1121

Phase 4 Completed

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT05201404 2025-04-29

LIVERATION

Phase 3 Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular, Liver Neoplasms

NCT05242900 2025-04-27

Imaging Sodium and Lymphatics in Lymphedema

Active not recruiting

Fibrosis, Lymphedema, Neoplasm Metastasis

NCT03507140 2025-04-20

BIM-LT

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT06908005 2025-04-08

RaFIST: A Radiomics-Based Tool for Intratumoral Fibrosis Stratification in Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung, Fibrosis