Clinical Trials

Phase 3 Active not recruiting

Brain Neoplasms, Glioblastoma, Glioma, Meningioma

NCT05095376 2026-05-19

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

265 enrolled

Glioblastoma, Gliosarcoma

NCT05500612 2026-05-19

MANGO

Recruiting

20 enrolled

Phase NA Not yet recruiting

Glioblastoma

NCT07590726 2026-05-19

PIRe

160 enrolled

Brain Injuries, Traumatic, Margins of Excision, Caregiver Burden, Brain Injuries, Brain Neoplasms, Communication, Glioblastoma, Neoplasms, Neurologic Manifestations, Stroke

NCT05432804 2026-05-18

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Phase 1/2 Recruiting

97 enrolled

Glioblastoma

NCT05871021 2026-05-18

PRIDE

146 enrolled

Glioblastoma

NCT07285044 2026-05-18

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

27 enrolled

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT07409584 2026-05-18

SHINE-GLIO

Recruiting

176 enrolled

Depression, Glioblastoma, Suicidal Ideation

NCT03911388 2026-05-15

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

24 enrolled

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT03970447 2026-05-15

GBM AGILE

Phase 2/3 Recruiting

2,250 enrolled

Glioblastoma, Recurrence

NCT06319027 2026-05-15

GABLE

100 enrolled

Glioblastoma

NCT06389591 2026-05-15

RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)

24 enrolled

Brain Neoplasms, Glioblastoma

NCT00906893 2026-05-14

MISOGLIO

Phase 2 Completed

14 enrolled

Hypoxia, Glioblastoma, Neoplasms

NCT04003649 2026-05-14

IL13Ra2-CAR T Cells With or Without Nivolumab and Ipilimumab in Treating Patients With GBM

20 enrolled

Glioblastoma

NCT04477200 2026-05-14

Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma

68 enrolled 20 charts

Phase EARLY_PHASE1 Completed

Glioblastoma, Gliosarcoma

NCT04614909 2026-05-14

Study of Pamiparib in Newly Diagnosed and rGBM

50 enrolled

Glioblastoma

NCT05281731 2026-05-14

Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma

Phase NA Recruiting

40 enrolled

Glioblastoma

NCT05739942 2026-05-14

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

42 enrolled

Phase EARLY_PHASE1 Terminated

Glioblastoma

NCT05773326 2026-05-14

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

5 enrolled

Glioblastoma, Glioma

NCT06934889 2026-05-14

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

60 enrolled

Phase NA Active not recruiting

Glioblastoma, Gliosarcoma

NCT07042620 2026-05-14

A Study to Test a New Fluid to Improve the Quality of Images Obtained by Using Sound Waves (Ultrasound) During Surgery

15 enrolled

Phase 1/2 Not yet recruiting

Glioblastoma, Glioma

NCT07392957 2026-05-14

Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma

54 enrolled

Phase EARLY_PHASE1 Recruiting

Glioblastoma

NCT07485049 2026-05-14

BGB-58067 in Newly Diagnosed Glioblastoma Patients With MTAP-Deleted Tumors

78 enrolled

Phase EARLY_PHASE1 Active not recruiting

Glioblastoma

NCT07585851 2026-05-14

Administration of Repurposed Ketoconazole in Glioma Patients

80 enrolled

CNSLymphoid

Glioblastoma, Lymphoma, Follicular

NCT05864534 2026-05-13

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

25 enrolled

Glioblastoma, Gliosarcoma

NCT06161519 2026-05-13

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Phase 1/2 Recruiting

146 enrolled

Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Recurrence

NCT06860594 2026-05-13

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Phase 1 Suspended

30 enrolled

CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT07244835 2026-05-13

A Study of DEG6498 in Participants With Solid Tumors

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

100 enrolled

Glioblastoma, Carcinoma, Hepatocellular, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Neurofibrosarcoma

NCT07422363 2026-05-13

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Phase 1 Not yet recruiting

30 enrolled

Phase 1 Not yet recruiting

Glioblastoma, Gliosarcoma

NCT07579208 2026-05-12

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

36 enrolled

Glioblastoma

NCT02192359 2026-05-11

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

18 enrolled 16 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT03975829 2026-05-11

Pediatric Long-Term Follow-up and Rollover Study

Phase 4 Recruiting

165 enrolled

CNSMyeloid

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Histiocytosis, Langerhans-Cell, Neuroblastoma, Neurofibromatosis 1, Oligodendroglioma, Ganglioglioma, Neurocytoma, Neurofibroma, Plexiform

NCT06973096 2026-05-11

CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy

9 enrolled

Glioblastoma

NCT07209241 2026-05-11

Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM

12 enrolled