Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 2 1Phase 1/2 1

Status

Unknown 3Active not recruiting 2

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Glioma 6Glioblastoma 5Brain Neoplasms 4Astrocytoma 3Oligodendroglioma 2Melanoma 2Pancreatic Neoplasms 1Gliosarcoma 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Breast Neoplasms 1

Interventions

Temozolomide 405Radiotherapy 202Bevacizumab 157Radiation 80Magnetic Resonance Spectroscopy 77Lomustine 49Surgical Procedures, Operative 45Carmustine 41pembrolizumab 40Irinotecan 38Nivolumab 32Specimen Handling 28Carboplatin 27Radiosurgery 24Erlotinib Hydrochloride 24Chemotherapy, Adjuvant 23Radiotherapy, Intensity-Modulated 22Drug Therapy 22Cyclophosphamide 20Aminolevulinic Acid 20O(6)-benzylguanine 17sargramostim 16Radiotherapy, Conformal 15Blood Specimen Collection 15temsirolimus 14Granulocyte-Macrophage Colony-Stimulating Factor 14Everolimus 14Vorinostat 13Sorafenib 13Ipilimumab 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Glioblastoma × Chlorotoxin × Clear all
NCT05627323 2026-01-29

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

Chimeric Therapeutics

Phase 1 Active not recruiting
42 enrolled
CNS

Glioblastoma

NCT04214392 2025-10-06

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

City of Hope Medical Center

Phase 1 Active not recruiting
19 enrolled
CNS

Glioblastoma, Glioma

NCT00591058 2009-07-17

Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma

TransMolecular

Phase 1 Unknown
36 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00683761 2009-07-17

A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma

TransMolecular

Phase 1/2 Unknown
64 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00114309 2009-04-03

131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma

TransMolecular

Phase 2 Unknown
66 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

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