Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1Lymphoid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 20Lymphoma, B-Cell 19Lymphoma, Large B-Cell, Diffuse 18Recurrence 13Lymphoma, Non-Hodgkin 13Multiple Myeloma 12Burkitt Lymphoma 11Lymphoma, Mantle-Cell 8Lymphoma 8Leukemia, Myeloid, Acute 8Carcinoma, Hepatocellular 7Pancreatic Neoplasms 6Neoplasms 6Lymphoma, Follicular 6Leukemia, Lymphocytic, Chronic, B-Cell 6Leukemia 5Glioma 5Colorectal Neoplasms 5Stomach Neoplasms 4Leukemia, B-Cell 4Hematologic Neoplasms 4Neoplasm, Residual 3Nasopharyngeal Carcinoma 3Melanoma 3Esophageal Neoplasms 3Breast Neoplasms 3Simpson-Golabi-Behmel syndrome 2Sarcoma, Synovial 2Sarcoma, Ewing 2Rhabdomyosarcoma 2

Interventions

Temozolomide 405Radiotherapy 202Bevacizumab 157Radiation 80Magnetic Resonance Spectroscopy 77Lomustine 49Surgical Procedures, Operative 45Carmustine 41pembrolizumab 40Irinotecan 38Nivolumab 32Specimen Handling 28Carboplatin 27Radiosurgery 24Erlotinib Hydrochloride 24Drug Therapy 23Chemotherapy, Adjuvant 23Radiotherapy, Intensity-Modulated 22Cyclophosphamide 20Aminolevulinic Acid 20O(6)-benzylguanine 17sargramostim 16Radiotherapy, Conformal 15Blood Specimen Collection 15temsirolimus 14Granulocyte-Macrophage Colony-Stimulating Factor 14Everolimus 14Vorinostat 13Sorafenib 13Ipilimumab 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Glioblastoma × Immunotherapy, Adoptive × Clear all
NCT06815029 2025-06-26

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

City of Hope Medical Center

Phase 1 Recruiting
27 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT02664363 2023-02-17

ExCeL

Duke University

Phase 1 Terminated
3 enrolled 8 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

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