Clinical Trials Browser

Phase 3 × Glioblastoma × Clear all

NCT05095376 2026-05-19

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Phase 3 Active not recruiting

Glioblastoma, Gliosarcoma

NCT07452458 2026-05-04

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Phase 3 Not yet recruiting

Glioblastoma

NCT06556563 2026-05-01

EF-41

Phase 3 Recruiting

Glioblastoma

NCT07195591 2026-04-30

BRIDGES

Phase 3 Recruiting

Glioblastoma, Neoplasms

NCT05902169 2026-04-24

SONOBIRD

Phase 3 Recruiting

Glioblastoma

NCT07100730 2026-04-16

IPAX BrIGHT

Phase 3 Recruiting

Brain Neoplasms, Glioblastoma, Neoplasm Recurrence, Local, Neoplasms, Central Nervous System Neoplasms

NCT01507506 2026-04-14

SPECTRO GLIO

Phase 3 Terminated

Glioblastoma

NCT06419946 2026-04-13

Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma

Phase 3 Recruiting

Glioblastoma

NCT06496971 2026-04-09

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

Phase 3 Recruiting

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue

NCT06388733 2026-04-01

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Phase 3 Recruiting

Brain Neoplasms, Glioblastoma

NCT03663725 2026-03-30

StrateGlio

Phase 3 Active not recruiting

Glioblastoma

NCT07461948 2026-03-10

Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients

Phase 3 Recruiting

Glioblastoma

NCT05303519 2026-03-05

SIGMA

Phase 3 Recruiting

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT06448286 2026-02-19

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

Phase 3 Not yet recruiting

Glioblastoma

NCT05904119 2026-02-17

LEGATO

Phase 3 Recruiting

Glioblastoma

NCT07376304 2026-01-29

BrainUS-AI

Phase 3 Not yet recruiting

Brain Neoplasms, Glioblastoma, Glioma

NCT05326464 2025-12-15

Tofacitinib in Recurrent GBM Patients

Phase 3 Active not recruiting

Glioblastoma

NCT02685605 2025-10-14

INTRAGO-II

Phase 3 Active not recruiting

Glioblastoma

NCT00807027 2025-10-10

Clinical Trial to Assess the Efficacy and Safety of 'Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of Korea

Phase 3 Completed

180 enrolled 8 charts

Glioblastoma

NCT01811121 2025-09-15

RESECT

Phase 3 Completed

Glioblastoma

NCT03149575 2025-09-04

STAR-3

Phase 3 Terminated

Brain Neoplasms, Glioblastoma, Glioma

NCT03345095 2025-07-01

MIRAGE

Phase 3 Completed

749 enrolled 15 charts

Glioblastoma

NCT05439278 2025-05-21

Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma

Phase 3 Recruiting

Glioblastoma

NCT03632135 2025-04-15

CSCRGBM

Phase 3 Completed

78 enrolled 10 charts

Brain Neoplasms, Glioblastoma

NCT02017717 2025-04-04

CheckMate 143

Phase 3 Completed

529 enrolled 28 charts

Glioblastoma

NCT06749925 2025-04-01

Clinical Trial Assessing the Efficacy and Safety of Dendritic Cell-Based Immunotherapy for Glioblastoma

Phase 3 Not yet recruiting

Glioblastoma

NCT05118776 2024-10-31

Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM

Phase 3 Active not recruiting

Glioblastoma

NCT05271240 2024-09-19

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Phase 3 Recruiting

Brain Neoplasms, Glioblastoma, Glioma

NCT06477939 2024-06-27

THREE-GLEES

Phase 3 Not yet recruiting

Hypoxia, Brain Neoplasms, Glioblastoma

NCT03776071 2024-04-22

A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1

Phase 3 Completed

Glioblastoma

NCT02546102 2024-04-03

Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma

Phase 3 Suspended

Glioblastoma

NCT03149003 2023-11-15

A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy

Phase 3 Completed

221 enrolled 17 charts

CNSGenitourinary

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Wilms Tumor

NCT00482677 2023-08-22

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 3 Completed

562 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT05718466 2023-07-17

Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy

Phase 3 Completed

35 enrolled 13 charts

Glioblastoma, Recurrence

NCT02573324 2023-05-11

Intellance1

Phase 3 Completed

691 enrolled 28 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT02761070 2023-03-08

RE-GEND

Phase 3 Unknown

Glioblastoma, Recurrence, Disease Progression

NCT03291977 2022-11-09

FLEGME

Phase 3 Completed

Glioblastoma

NCT05600491 2022-10-31

A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme

Phase 3 Unknown

Glioblastoma

NCT03243461 2022-06-06

HIT-HGG-2013

Phase 3 Unknown

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial

NCT00045968 2022-05-18

GBM

Phase 3 Unknown

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00369785 2021-10-20

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Phase 3 Completed

198 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Fatigue, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Radiation Injuries, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00031798 2021-09-09

Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors

Phase 3 Terminated

Astrocytoma, Brain Neoplasms, Depression, Ependymoma, Fatigue, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT03393000 2021-07-22

INTACT

Phase 3 Terminated

19 enrolled 8 charts

Glioblastoma

NCT03419403 2021-04-14

UNITE Study: Understanding New Interventions With GBM ThErapy

Phase 3 Terminated

40 enrolled 16 charts

Glioblastoma, Neoplasms

NCT04829097 2021-04-02

Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma

Phase 3 Unknown

Glioblastoma

NCT01290939 2021-02-15

Bevacizumab and Lomustine for Recurrent GBM

Phase 3 Completed

Brain Neoplasms, Cognition Disorders, Glioblastoma

NCT04536649 2020-09-02

Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma.

Phase 3 Unknown

Glioblastoma

NCT00304031 2020-06-09

Radiation Therapy (RT) and Temozolomide (TMZ) in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Phase 3 Completed

1,173 enrolled 33 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01805453 2020-05-08

ASTER

Phase 3 Completed

Edema, Glioblastoma

NCT04277221 2020-03-17

ADCTA for Adjuvant Immunotherapy in Standard Treatment of Recurrent Glioblastoma Multiforme (GBM)

Phase 3 Unknown

Glioblastoma