Clinical Trials

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT05546372 2026-05-26

RACCOON

122 enrolled

Klatskin Tumor

NCT05874934 2026-05-26

CHORDA-II-p

Phase NA Completed

40 enrolled

Phase 2 Active not recruiting

Klatskin Tumor

NCT05564403 2026-05-13

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

66 enrolled

Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT07030140 2026-05-01

Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar Cholangiocarcinoma

Phase 2 Recruiting

38 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06125769 2026-04-03

LITALHICA

50 enrolled

Klatskin Tumor

NCT07454486 2026-03-06

TRACE-BTC

300 enrolled

Phase 3 Active not recruiting

Biliary Tract Neoplasms, Gallbladder Neoplasms, Neoplasms, Cholangiocarcinoma, Klatskin Tumor, Neoplasm, Residual

NCT06109779 2026-03-04

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

757 enrolled

Phase 2 Active not recruiting

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06178588 2026-02-24

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

15 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT05430698 2026-02-09

PD-1 Antibody Plus GEMOX as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma

Phase 2 Recruiting

62 enrolled

Klatskin Tumor

NCT06739252 2026-01-28

Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCA

Phase 2 Terminated

1 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma, Klatskin Tumor

NCT05993429 2026-01-26

Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma

200 enrolled

Phase NA Not yet recruiting

Cholangiocarcinoma, Klatskin Tumor

NCT07326189 2026-01-16

PHAE-PHCC

33 enrolled

Klatskin Tumor

NCT07311798 2025-12-31

Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective Study

300 enrolled

Phase NA Not yet recruiting

Klatskin Tumor

NCT03104569 2025-12-26

Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma

100 enrolled

Cholangitis, Klatskin Tumor

NCT06420349 2025-12-22

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Phase 1 Terminated

7 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT05024513 2025-12-18

Biliary Drainage Plus HAIC in Locally Advanced pCCA

127 enrolled

Klatskin Tumor

NCT07176962 2025-09-16

A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers Screening

Recruiting

1,800 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Disease, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT07161869 2025-09-09

POELH-III

250 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Biliary Tract Neoplasms, Common Bile Duct Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT07149558 2025-09-02

Volume-Restricted Resection for Perihilar Cholangiocarcinoma

300 enrolled

Klatskin Tumor

NCT06850753 2025-08-21

SURE-LT

15 enrolled

Klatskin Tumor

NCT05678218 2025-08-08

POELH-II

245 enrolled

Adenocarcinoma, Common Bile Duct Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT04993131 2025-07-31

TESLA II

15 enrolled

Bile Duct Neoplasms, Klatskin Tumor

NCT03377179 2025-07-23

A Study of ABC294640 Alone and in Combination With HCQ Sulfate in the Treatment of Advanced Cholangiocarcinoma

65 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT06493734 2025-07-15

STRONG II

30 enrolled

Klatskin Tumor

NCT04561453 2025-07-10

Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer

Terminated

14 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06964425 2025-07-02

Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study

20 enrolled

Disease, Cholangiocarcinoma, Klatskin Tumor

NCT06986486 2025-05-23

pCOLA

Recruiting

8 enrolled

Klatskin Tumor

NCT05239169 2025-05-01

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

40 enrolled

Phase 2/3 Not yet recruiting

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06923475 2025-04-11

NEODISCO

150 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT05551299 2025-03-27

CARP

Phase 4 Recruiting

258 enrolled

Bile Duct Neoplasms, Klatskin Tumor

NCT03414489 2025-03-18

Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)

No longer available

Cholangiocarcinoma, Klatskin Tumor

NCT06720883 2024-12-06

ROBOCHOL

Recruiting

32 enrolled

Phase 2 Active not recruiting

Congenital contractural arachnodactyly, Cholangiocarcinoma, Klatskin Tumor

NCT06717464 2024-12-05

Toripalimab Combined With Capecitabine as Postoperative Adjuvant Therapy for Patients With Resectable Advanced Extrahepatic Biliary Tract Cancer

110 enrolled

Gallbladder Neoplasms, Klatskin Tumor

NCT06658587 2024-10-26

A Novel Serological Risk Model for Early Non-invasive Diagnosis of Cholangiocarcinoma

60 enrolled

Disease, Cholangiocarcinoma, Klatskin Tumor

NCT06357117 2024-04-11

Extent of Intrahepatic Infiltration of Perihilar Cholangiocarcinoma

62 enrolled

Klatskin Tumor

NCT05563870 2024-03-26

COMBO-RFA

30 enrolled

Klatskin Tumor

NCT01825603 2023-12-28

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Phase 1 Completed

17 enrolled

Phase NA Not yet recruiting

Gallbladder Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06175845 2023-12-19

ACTICCA-2

130 enrolled

Bile Duct Neoplasms, Bites and Stings, Cholangitis, Liver Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06106750 2023-10-30

Endoscopic Scissors Cutting Nasobiliary Duct VS Bilateral Plastic Stent

122 enrolled

Bile Duct Diseases, Gallbladder Diseases, Klatskin Tumor

NCT05681949 2023-08-24

ADBoard

1,200 enrolled

Fibrolamellar hepatocellular carcinoma, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Cholangiocarcinoma, Klatskin Tumor

NCT03003065 2023-08-22

PDT

10 enrolled

Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT04211168 2023-03-29

Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers

Phase 2 Unknown

44 enrolled

Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT05626127 2022-11-23

MRI-based Clinico-radiomics Predicting Lymph Node Metastasis Status of Hilar Cholangiocarcinoma

Unknown

60 enrolled

Lymphatic Metastasis, Klatskin Tumor

NCT03353181 2022-08-25

ENBD

Phase NA Withdrawn

Klatskin Tumor

NCT05402618 2022-06-02

Minimally Invasive Versus Open Surgery for PHC

783 enrolled

Klatskin Tumor

NCT04611100 2022-03-23

Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma

Phase NA Completed

70 enrolled

Klatskin Tumor

NCT02232932 2021-11-03

TRANSPHIL

60 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT05078801 2021-10-15

Endoscopic Versus Radiologic Biliary Drainage for Perihilar Malignant Obstruction

Unknown

100 enrolled