NCT07415018 2026-04-14
Optimizing Contrast Dose and Scanning Parameters for Detection of Leptomeningeal Disease
M.D. Anderson Cancer Center
Phase NA Not yet recruiting
Clinical Trials
13 trialsNCT06146010 2026-04-08
Non Interventional German Leptomeningeal Disease Register
University Hospital Tuebingen
Recruiting
NCT03025256 2026-04-02
Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT05809752 2026-04-01
A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Recruiting
NCT02422641 2026-03-23
Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis
Wake Forest University Health Sciences
Phase 2 Recruiting
NCT00338377 2026-03-20
Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma
M.D. Anderson Cancer Center
Phase 2 Active not recruiting
NCT07476781 2026-03-17
CSF and Blood Plasma Liquid Biopsy in Patients With Metastatic Solid Tumours and CNS Metastases or no CNS Metastases
Sunnybrook Health Sciences Centre
Phase NA Recruiting
NCT05865990 2026-03-12
TUXEDO-3
MedSIR
Phase 2 Active not recruiting
NCT04988009 2026-03-05
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology
M.D. Anderson Cancer Center
Recruiting
NCT03719768 2026-03-02
Avelumab With Radiotherapy in Patients With Leptomeningeal Disease
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Completed
NCT06016387 2026-02-23
Tucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in Patients With HER2+, HER2 Mutated and/or HER2-amplified Metastatic Breast Cancer and Leptomeningeal Disease: A Multi-centre Phase II, Single Arm Feasibility Study
Sunnybrook Health Sciences Centre
Phase 2 Recruiting
NCT04588545 2026-02-09
Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease
H. Lee Moffitt Cancer Center and Research Institute
Phase 1/2 Recruiting
NCT07390539 2026-02-05
B7-H3.CD28Z.CART in CNS Neoplasms
Dana-Farber Cancer Institute
Phase 1 Not yet recruiting