NCT03025256 2026-04-02
Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease
M.D. Anderson Cancer Center
Phase 1 Recruiting
Clinical Trials
14 trialsNCT05809752 2026-04-01
A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Recruiting
NCT03719768 2026-03-02
Avelumab With Radiotherapy in Patients With Leptomeningeal Disease
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Completed
NCT07390539 2026-02-05
B7-H3.CD28Z.CART in CNS Neoplasms
Dana-Farber Cancer Institute
Phase 1 Not yet recruiting
NCT03423628 2025-12-22
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
AstraZeneca
Phase 1 Recruiting
NCT04250545 2025-11-25
Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer
National Cancer Institute (NCI)
Phase 1 Active not recruiting
NCT07098806 2025-08-01
CA2024-LM-001
Plus Therapeutics
Phase 1 Recruiting
NCT05112549 2025-04-03
IT-PD1
University Hospital Tuebingen
Phase 1 Recruiting
NCT03711422 2022-06-14
Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC
National Cancer Centre, Singapore
Phase 1 Terminated
NCT00062881 2020-03-04
Intrathecal Mafosfamide
Baylor College of Medicine
Phase 1 Completed
NCT00512460 2016-05-16
RTA 744 Injection in Patients With Leptomeningeal Disease
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT00001251 2013-08-19
Phase I Study of Intrathecal Mafosfamide
National Institutes of Health Clinical Center (CC)
Phase 1 Completed
NCT00515788 2012-03-12
DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT00001333 2008-03-04
Phase I Study of Intrathecal Topotecan
National Institutes of Health Clinical Center (CC)
Phase 1 Completed