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Clinical Trials

164 trials
RecentStart dateEnrollment
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Phase

Phase 2 67Phase NA 14Phase 3 14Phase 1/2 12Phase 1 10Phase 2/3 8Phase 4 6Phase EARLY_PHASE1 2

Status

Unknown 48Recruiting 34Completed 30Not yet recruiting 23Terminated 12Active not recruiting 12Withdrawn 3Suspended 2

Sponsor Class

OTHER 112INDUSTRY 47OTHER_GOV 3NETWORK 2

Study Type

Interventional 133Observational 31

Sponsor

Cancer Type

Thoracic 164Other solid neoplasm 2Breast 1

Conditions

Breast Neoplasms 12989Neoplasms 10382Carcinoma, Non-Small-Cell Lung 6793Prostatic Neoplasms 6196Colorectal Neoplasms 5862Lung Neoplasms 5040Multiple Myeloma 3541Pancreatic Neoplasms 3511Neoplasm Metastasis 3478Leukemia, Myeloid, Acute 3467Carcinoma, Hepatocellular 3227Ovarian Neoplasms 3138Melanoma 3120Stomach Neoplasms 3019Lymphoma 2970Head and Neck Neoplasms 2575Recurrence 2527Precursor Cell Lymphoblastic Leukemia-Lymphoma 2485Leukemia 2353Colonic Neoplasms 2317Brain Neoplasms 2293Lymphoma, Non-Hodgkin 2257Rectal Neoplasms 2171Uterine Cervical Neoplasms 2164Glioblastoma 1993Leukemia, Lymphocytic, Chronic, B-Cell 1985Carcinoma, Renal Cell 1897Squamous Cell Carcinoma of Head and Neck 1856Lymphoma, Follicular 1829Esophageal Neoplasms 1786

Interventions

Pemetrexed 14Carboplatin 12osimertinib 11Drug Therapy 9aflutinib 8Gefitinib 8Radiotherapy 6Docetaxel 6Cisplatin 6pembrolizumab 5anlotinib 5Radiosurgery 5icotinib 4Vinorelbine 4Paclitaxel 4Gemcitabine 4Erlotinib Hydrochloride 4tislelizumab 3camrelizumab 3apatinib 3HM781-36B 3toripalimab 2spartalizumab 2rezivertinib 2dacomitinib 2Tyrosine Kinase Inhibitors 2Thalidomide 2Surgical Procedures, Operative 2S 1 (combination) 2Platinum 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements
NCT07530744 2026-04-15

Cronos

Elisabethinen Hospital

Phase NA Not yet recruiting
20 enrolled
Thoracic

NSCLC

NCT00280189 2026-04-14

Study of Outcomes of Radiofrequency Ablation of Lung Tumors

University of Pittsburgh

Suspended
72 enrolled
Thoracic

NSCLC

NCT06865339 2026-04-13

TRIPL

Montefiore Medical Center

Phase 2 Recruiting
76 enrolled
Thoracic

NSCLC

NCT07516015 2026-04-07

Clinical Effectiveness and Safety of SHR-A1811 in Chinese Patients With HER2-Altered NSCLC

Nanjing Tianyinshan Hospital

Not yet recruiting
1,000 enrolled
Thoracic

NSCLC

NCT03606070 2026-03-23

IMAHTEP

Gustave Roussy, Cancer Campus, Grand Paris

Phase NA Terminated
11 enrolled
Thoracic

NSCLC

NCT06738160 2026-03-20

The Efficacy and Safety of Narlumosbart in Combination With Stereotactic Body Radiation Therapy to Improve the Efficacy of First-line Chemotherapy Combined With Immunotherapy in Patients With Bone Metastases From Advanced Non-small Cell Lung Cancer

Fudan University

Phase 2 Recruiting
27 enrolled
Thoracic

NSCLC

NCT07388771 2026-03-19

Prediction of Outcome to Neoadjuvant Therapy in Non-small Cell Lung Cancer(NSCLC)

Tongji Hospital

Recruiting
500 enrolled
Thoracic

NSCLC

NCT05798845 2026-03-11

The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer

Shanghai Chest Hospital

Phase 2 Recruiting
124 enrolled
Thoracic

NSCLC

NCT05636267 2026-03-09

Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients

Akeso

Phase 1/2 Terminated
59 enrolled
Thoracic

NSCLC

NCT04318938 2026-03-02

Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping

Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

Phase 2 Active not recruiting
118 enrolled
Thoracic

NSCLC

NCT05378763 2026-02-18

PINNACLE

Spectrum Pharmaceuticals, Inc

Phase 3 Suspended
268 enrolled
Thoracic

NSCLC

NCT07413952 2026-02-17

Limertinib Plus Radiotherapy for EGFR-Mutant NSCLC With Brain Metastases

The First Affiliated Hospital of Guangzhou Medical University

Phase 2 Not yet recruiting
45 enrolled
Thoracic

NSCLC

NCT05714891 2026-02-12

Neoadjuvant Platform Trial in Non-Small Cell Lung Cancer

Canadian Cancer Trials Group

Phase 2 Active not recruiting
4 enrolled
Thoracic

NSCLC

NCT07082179 2026-02-11

A Prospective Phase II Clinical Study of Immunotherapy Combined With Chemotherapy for Stage III Unresectable Non-small Cell Lung Cancer

Jiangsu Cancer Institute & Hospital

Phase 2 Recruiting
33 enrolled
Thoracic

NSCLC

NCT07376382 2026-02-02

SYNSTAR-02

CSPC Megalith Biopharmaceutical Co.,Ltd.

Phase 3 Not yet recruiting
450 enrolled
Thoracic

NSCLC

NCT07379398 2026-01-30

Iparomlimab and Tuvonralimab Injection Combined With SBRT in Patients With Early-Stage Non-Small Cell Lung Cancer

Tianjin Medical University Cancer Institute and Hospital

Phase 2 Not yet recruiting
28 enrolled
Thoracic

NSCLC

NCT04557007 2026-01-29

Oncomabs

Oslo University Hospital

Terminated
80 enrolled
Thoracic

NSCLC

NCT07358689 2026-01-22

Toripalimab Combined With Platinum-based Chemotherapy With or Without H1 Receptor Antagonist in the Perioperative Treatment of Resectable Non-small Cell Lung Cancer

Tianjin Medical University Cancer Institute and Hospital

Phase 2 Not yet recruiting
120 enrolled
Thoracic

NSCLC

NCT06576635 2026-01-20

LUNG-05

University of Illinois at Chicago

Phase NA Recruiting
29 enrolled
Thoracic

NSCLC

NCT05089916 2026-01-14

ROSE

AIO-Studien-gGmbH

Phase 2 Active not recruiting
42 enrolled
Thoracic

NSCLC

NCT07330037 2026-01-09

TALENT Study: Phase II Trial of Adjuvant L-TIL Plus Tislelizumab in Resectable NSCLC Without pCR After Neoadjuvant Chemoimmunotherapy

Tianjin Medical University Cancer Institute and Hospital

Phase 2 Recruiting
41 enrolled
Thoracic

NSCLC

NCT04640259 2025-12-18

EoYLC

Addario Lung Cancer Medical Institute

Active not recruiting
250 enrolled
Thoracic

NSCLC

NCT07169552 2025-12-17

HC010 in First-line PD-L1 Positive Advanced NSCLC Patients

HC Biopharma Inc.

Phase 2 Recruiting
50 enrolled
Thoracic

NSCLC

NCT07281209 2025-12-15

A Study of SHR-A1811 Combined With Adebelimumab as Neoadjuvant Therapy for Resectable HER2-Altered Non-Small Cell Lung Cancer

Shanghai Chest Hospital

Phase 2 Not yet recruiting
40 enrolled
Thoracic

NSCLC

NCT07247227 2025-11-25

Real-world First-line Sugemalimab-Chemotherapy in Advanced NSCLC

Peking Union Medical College

Phase NA Recruiting
150 enrolled
Thoracic

NSCLC

NCT07243899 2025-11-24

Multimodal Model Predicts Treatment Efficacy and CIP Risk in Advanced NSCLC With Immunotherapy and Chemotherapy

Shanghai Zhongshan Hospital

Completed
3,000 enrolled
Thoracic

NSCLC

NCT04858958 2025-11-19

FAVOUR

Allist Pharmaceuticals, Inc.

Phase 1 Active not recruiting
30 enrolled
Thoracic

NSCLC

NCT05466149 2025-11-19

Efficacy and Safety of Furmonertinib in Patients With Locally Advanced or Metastatic NSCLC With EGFR Exon 20 Insertion

Allist Pharmaceuticals, Inc.

Phase 2 Active not recruiting
100 enrolled
Thoracic

NSCLC

NCT07181499 2025-09-30

Sequential Chemotherapy With Befotertinib in Non-Small Cell Lung Cancer (NSCLC) Patients With Resistance to Third-Generation EGFR-TKI

Betta Pharmaceuticals Co., Ltd.

Phase 2 Recruiting
28 enrolled
Thoracic

NSCLC

NCT07198217 2025-09-30

Real World Study of Platinum Containing Dual Drug Chemotherapy Followed by Large Fractionated Radiotherapy Combined withTislelizumab in Stage IIIB/C-IV Non-small Cell Lung Cancer Patient

Zibo Municipal Hospital

Phase 2 Recruiting
20 enrolled
Thoracic

NSCLC

NCT06448910 2025-09-24

Cadonilimab(AK104) Plus Concurrent Chemoradiotherapy in Patients With Locally Advanced, Unresectable, Stage III NSCLC

Fudan University

Phase 2 Active not recruiting
41 enrolled
Thoracic

NSCLC

NCT07179445 2025-09-17

Analysis of Deoxyribonucleic Acid and Ribonucleic Acid Next-Generation Sequencing in Non-Small Cell Lung Cancer Patients Without Pathological Complete Response Following Neoadjuvant Immunotherapy

Tianjin Medical University Cancer Institute and Hospital

Not yet recruiting
300 enrolled
Thoracic

NSCLC

NCT07156604 2025-09-05

Vebreltinib for Neoadjuvant in METex 14 Skipping Mutant Stage IIA-IIIB (N2) Non-small Cell Lung Cancer (NSCLC)

Fudan University

Phase 2 Not yet recruiting
30 enrolled
Thoracic

NSCLC

NCT07153770 2025-09-04

Bozitinib Combined With Chemotherapy as Radical Treatment for Stage IIA-IIIC MET-Altered Non-Small Cell Lung Cancer

Shanghai Pulmonary Hospital, Shanghai, China

Phase 2 Not yet recruiting
34 enrolled
Thoracic

NSCLC

NCT05773092 2025-09-03

A Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC

National Cancer Centre, Singapore

Phase 2 Active not recruiting
30 enrolled
Thoracic

NSCLC

NCT07134413 2025-08-21

QL1706/Bevacizumab ± Chemotherapy in Post-ICI Non-Squamous NSCLC

Guangdong Association of Clinical Trials

Phase 2 Not yet recruiting
77 enrolled
Thoracic

NSCLC

NCT05078931 2025-07-30

A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients

Shanghai Chest Hospital

Phase 2 Active not recruiting
35 enrolled
Thoracic

NSCLC

NCT07089199 2025-07-28

TitAN

Qilu Hospital of Shandong University

Phase 2 Not yet recruiting
34 enrolled
Thoracic

NSCLC

NCT06864624 2025-07-25

WU-KONG20

Tang-Du Hospital

Phase 2 Recruiting
27 enrolled
Thoracic

NSCLC

NCT07085182 2025-07-25

Tislelizumab Combined With sCRT in Stage IIIB/C-IV Non-Squamous Non-Small Cell Lung Cancer:A Prospective, Single-Arm, Phase II Study

Zibo Municipal Hospital

Phase 2 Recruiting
20 enrolled
Thoracic

NSCLC

NCT07086326 2025-07-25

NEOINSPIRE

Peking University People's Hospital

Phase 2 Not yet recruiting
164 enrolled
Thoracic

NSCLC

NCT02284308 2025-07-04

ELDAPT

Maastricht Radiation Oncology

Active not recruiting
180 enrolled
Thoracic

NSCLC

NCT06754644 2025-06-10

A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC

Qilu Pharmaceutical Co., Ltd.

Phase 3 Recruiting
808 enrolled
Thoracic

NSCLC

NCT04820023 2025-06-06

Phase 1/2 Study of BBT-176 in Advanced NSCLC With Progression After EGFR TKI Treatment

Bridge Biotherapeutics, Inc.

Phase 1/2 Terminated
45 enrolled 19 charts
Thoracic

NSCLC

NCT06940401 2025-05-14

JS111 in Patients With Advanced NSCLC Harboring EGFR Mutations

Suzhou Junjing BioSciences Co., Ltd.

Phase 1/2 Recruiting
42 enrolled
Thoracic

NSCLC

NCT05994131 2025-04-30

IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLC

InxMed (Shanghai) Co., Ltd.

Phase 1/2 Recruiting
110 enrolled
Thoracic

NSCLC

NCT06944470 2025-04-25

JS207 Combined With Chemotherapy in Subjects With Stage II-III NSCLC

Shanghai Junshi Bioscience Co., Ltd.

Phase 2 Not yet recruiting
76 enrolled
Thoracic

NSCLC

NCT02973763 2025-04-03

Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of Alflutinib in Advanced Non Small Cell Lung Cancer

Allist Pharmaceuticals, Inc.

Phase 1 Terminated
14 enrolled
Thoracic

NSCLC

NCT06457789 2025-04-02

iRelate

Amsterdam UMC, location VUmc

Phase NA Recruiting
34 enrolled
Thoracic

NSCLC

NCT06893354 2025-03-25

Explore the Mechanisms Underlying Disease Resistance and Potential Primary Resistance Mechanism of Induction Therapy Lorlatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Positive Mutation Revealed by Single-cell RNA Sequencing and Spatial Transcriptomics

The First Affiliated Hospital of Guangzhou Medical University

Phase 4 Not yet recruiting
20 enrolled
Thoracic

NSCLC

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