Clinical Trials

1,500 enrolled

Neoplastic Syndromes, Hereditary, Li-Fraumeni Syndrome

NCT07461246 2026-03-10

RIPAF

Phase NA Enrolling by invitation

1,500 enrolled

GastrointestinalSarcoma

Turcot syndrome, Attenuated familial adenomatous polyposis, Polyposis Syndrome, Hereditary Mixed, 1, Gardner Syndrome, Neoplastic Syndromes, Hereditary, Adenomatous Polyposis Coli, Colorectal Neoplasms, Desmoid Tumors

NCT07053813 2026-02-27

CARE-HCS

900 enrolled

Neoplastic Syndromes, Hereditary

NCT06654466 2026-02-25

Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer

100 enrolled

Neoplastic Syndromes, Hereditary

NCT02958462 2026-02-23

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

Classical hematologyOther hematologic neoplasm

2,000 enrolled

Bone Marrow Failure Disorders, Congenital Bone Marrow Failure Syndromes, Cytopenia, Neoplastic Syndromes, Hereditary, Hematologic Neoplasms

NCT07195071 2026-02-18

FOCUS

1,000 enrolled

Neoplastic Syndromes, Hereditary

NCT05079334 2026-02-10

FOREST

Phase NA Enrolling by invitation

1,847 enrolled 8 charts

Neoplastic Syndromes, Hereditary

NCT07381985 2026-02-02

LINC

200 enrolled

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary

NCT04494945 2026-01-23

Identifying and Caring for Individuals With Inherited Cancer Syndrome

27,500 enrolled

Carcinoma, Intraductal, Noninfiltrating, Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT04261972 2026-01-14

CHARM1

1,416 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplasms, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT05664867 2026-01-14

TestMiGenes

80 enrolled

Neoplastic Syndromes, Hereditary

NCT05721326 2026-01-13

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

Phase NA Completed

1,330 enrolled

BreastGynecologic

Breast Neoplasms, Neoplastic Syndromes, Hereditary, Ovarian Neoplasms, Genetic Predisposition to Disease, Genetic Diseases, Inborn, Hereditary Breast and Ovarian Cancer Syndrome

NCT07052266 2025-12-26

FOCUS

550 enrolled

Neoplastic Syndromes, Hereditary

NCT06726642 2025-12-16

CHARM2

1,000 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Stomach Neoplasms, Li-Fraumeni Syndrome, Hereditary Breast and Ovarian Cancer Syndrome

NCT03857594 2025-12-03

INSIGHT

10 enrolled

Neoplastic Syndromes, Hereditary

NCT06218433 2025-11-18

Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study)

GastrointestinalGenitourinary

200 enrolled

Urogenital Diseases, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary

NCT06927947 2025-10-16

Navigation Interventions to Improve Cascade Genetic Testing Among Relatives of Patients With Hereditary Cancer Syndromes

500 enrolled

Neoplastic Syndromes, Hereditary

NCT03160274 2025-10-15

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

CNSEndocrineGenitourinaryHead & NeckSarcoma

2,000 enrolled

Bone Neoplasms, Kidney Neoplasms, Neoplastic Syndromes, Hereditary, Paraganglioma, Pheochromocytoma, Thyroid Neoplasms

NCT04763915 2025-09-19

IMPACT

Phase NA Active not recruiting

720 enrolled

BreastGastrointestinalGenitourinaryGynecologic

Breast Neoplasms, Neoplastic Syndromes, Hereditary, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT03426878 2025-09-11

CHARM

Phase NA Completed

967 enrolled 13 charts

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT06096688 2025-09-04

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

GastrointestinalGynecologic

1,120 enrolled

Carcinoma, Neoplastic Syndromes, Hereditary, Polyps, Colorectal Neoplasms, Endometrial Neoplasms

NCT05470920 2025-08-13

Genetic Testing Decision Aid

Phase NA Enrolling by invitation

350 enrolled

Gynecologic

Carcinoma, Ovarian Epithelial, Neoplastic Syndromes, Hereditary

NCT06914726 2025-08-05

PC-CDS

2,488 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT05562778 2025-07-28

Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment

150 enrolled

Neoplastic Syndromes, Hereditary

NCT06999954 2025-05-31

SDS-GPS

Classical hematologyGastrointestinalLymphoidMyeloid

8,000 enrolled

Neutropenia, severe chronic, Neutropenia, Severe Congenital, Autosomal Recessive 3, Congenital Bone Marrow Failure Syndromes, Shwachman-Diamond Syndrome, Primary Immunodeficiency Diseases, Immunologic Deficiency Syndromes, Lymphoma, Follicular, Myelodysplastic Syndromes, Neoplastic Syndromes, Hereditary, Exocrine Pancreatic Insufficiency, Pancytopenia

NCT04903782 2022-11-04

PREDICT

270 enrolled

Disease Susceptibility, Neoplasms, Neoplastic Syndromes, Hereditary, Genetic Predisposition to Disease

NCT03973450 2021-09-08

EpidemioPIT

Unknown

400 enrolled

EndocrineHead & Neck

Endocrine Gland Neoplasms, Hyperparathyroidism, Neoplastic Syndromes, Hereditary, Pituitary Neoplasms

NCT04510896 2021-07-30

Inherited Risk Evaluation Tool (InheRET): Identifying Patients at Increased Risk for Hereditary Disease

Phase NA Unknown

2,232 enrolled

Neoplastic Syndromes, Hereditary

NCT02289326 2019-09-19

Biomarker Monitoring in TP53 Mutation Carriers

Completed

6 enrolled

Neoplastic Syndromes, Hereditary, Li-Fraumeni Syndrome

NCT03979612 2019-06-07

GENEPY

Unknown

450 enrolled