Clinical Trials

Neurofibromatosis 1, Neurofibromatoses

NCT07233408 2026-02-27

Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy

Phase NA Recruiting

50 enrolled

Phase NA Active not recruiting

Neurofibromatosis 1, Neurofibromatoses

NCT03873610 2025-12-26

Resiliency Training in Adolescents With NF1 and NF2

200 enrolled

Neurofibromatoses

NCT03406208 2025-12-24

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

228 enrolled

Schwannomatosis, Behavior, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT06961565 2025-12-04

PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas

Phase 1 Recruiting

56 enrolled

Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT07237100 2025-11-19

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Phase 2 Recruiting

10 enrolled

CNSDermatologic

Melanoma, Neurofibromatoses

NCT05581511 2025-10-14

cNF Natural Hx

Active not recruiting

500 enrolled

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT06262113 2025-10-03

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Phase NA Recruiting

294 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT05489783 2025-06-29

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

Recruiting

50 enrolled

Glioma, Neurofibromatoses

NCT03231306 2025-05-02

NF108-BINI

45 enrolled 8 charts

Neurofibroma, Neurofibromatosis 1, Peripheral Nervous System Neoplasms, Neurofibromatoses, Neurofibroma, Plexiform

NCT05196854 2025-02-24

Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

54 enrolled

Hypertension, Neurofibromatosis 1, Neurofibromatoses

NCT01639950 2024-06-21

Validating Pain Scales in Children and Young Adults

CNSClassical hematologyOther hematologic neoplasm

252 enrolled

Anemia, Sickle Cell, Leukemia, Pain, Neurofibromatoses

NCT05438290 2024-05-06

DPCP to Treat Cutaneous Neurofibromas Associated With NF1

Phase 1 Completed

17 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT05011019 2024-03-21

A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis

Phase 1/2 Terminated

22 enrolled

CNSSarcoma

Neurofibromatoses, Neurofibrosarcoma

NCT04474678 2024-01-09

Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")

CNSOther hematologic neoplasmSarcoma

240 enrolled

Brain Neoplasms, Hematologic Diseases, Leukemia, Neuroblastoma, Sarcoma, Neurofibromatoses

NCT05377008 2023-09-22

OPTIMAL-SSI

38 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT04463316 2023-09-06

GROW UR GENES

Recruiting

600 enrolled

Blepharophimosis syndrome Ohdo type, Tetrasomy X, Allan-Herndon-Dudley syndrome, Acrocephalosyndactylia, Adrenal Hyperplasia, Congenital, De Lange Syndrome, DiGeorge Syndrome, Klinefelter Syndrome, Noonan Syndrome, Prader-Willi Syndrome, Disorders of Sex Development, Tuberous Sclerosis, Turner Syndrome, Rett Syndrome, Neurofibromatoses, Kallmann Syndrome, Williams Syndrome, Bardet-Biedl Syndrome, Jacobsen Distal 11q Deletion Syndrome, 22q11 Deletion Syndrome, Disorder of Sex Development, 46,XY, CHARGE Syndrome

NCT01885767 2023-08-30

Neurofibromatosis (NF) Registry Portal

Recruiting

20,000 enrolled

Schwannomatosis, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT02101736 2023-05-24

NF105-CABO

45 enrolled 10 charts

Neurofibromatoses, Neurofibroma, Plexiform

NCT05779527 2023-03-22

Mindful Parenting - A Single Case Experimental Design Study

Phase NA Unknown

12 enrolled

Alopecia, Cleft Lip, Skin Diseases, Neurofibromatoses

NCT04461886 2022-05-24

A Long-term Study of NPC-12G Gel in Neurofibromatosis Type I

Phase 3 Terminated

100 enrolled

Neurofibromatoses

NCT05107037 2021-11-04

A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of TQ-B3234 in Patients With Type I Neurofibromatosis

Phase 1 Unknown

120 enrolled

Neurofibromatoses

NCT01682811 2021-06-18

Phase I Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)

Phase 1 Completed

20 enrolled 11 charts

Neurofibromatoses

NCT03513757 2020-02-21

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Phase 4 Completed

40 enrolled 15 charts

Abdominal Neoplasms, Epilepsy, Headache, Hydrocephalus, Neoplasms, Neurofibromatoses

NCT00824278 2019-12-17

The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory Pilot Study

289 enrolled

Neoplasms, HIV Infections, Neurofibromatoses

NCT01222728 2019-12-17

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

5 enrolled

Phase EARLY_PHASE1 Completed

Neoplasms, Nervous System Diseases, Neuroma, Acoustic, Vestibular Diseases, Neurofibromatosis 2, Neurofibromatoses

NCT01633008 2019-09-30

Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic Pain

28 enrolled

Depression, Neurofibromatoses

NCT00911248 2019-04-12

PTC299 for Treatment of Neurofibromatosis Type 2

Phase 2 Terminated

11 enrolled

Neurofibromatosis 2, Neurofibromatoses

NCT00303368 2019-02-25

NF1TD

395 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT02387177 2018-08-17

Resiliency Training for Adolescent Neurofibromatosis Patients Via Videoconferencing With Skype

51 enrolled

Neurofibromatoses

NCT00021541 2018-04-17

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

62 enrolled 13 charts

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT01402817 2018-03-14

Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas

Phase 2 Terminated

19 enrolled 8 charts

Neurofibromatoses, Neurofibroma, Plexiform

NCT03359304 2017-12-02

The Neurofibromatosis-associated Tumor Biobank

Not yet recruiting

300 enrolled

CNSSarcoma

Bone Neoplasms, Neurofibromatoses

NCT01410006 2017-07-25

NPRI

2,391 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT01140360 2017-07-02

0908-09

Phase 1/2 Completed

21 enrolled 8 charts

Phase EARLY_PHASE1 Completed

Neurofibroma, Neurofibromatoses

NCT01275586 2017-04-12

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

6 enrolled 7 charts

Neurofibroma, Neurofibromatoses, Neurofibroma, Plexiform

NCT02435628 2017-04-04

Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NF

86 enrolled

Neurofibromatoses

NCT02298270 2016-06-23

Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype

65 enrolled

Schwannomatosis, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT01673009 2016-04-06

Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

36 enrolled 8 charts

Neurofibromatoses

NCT00589784 2016-01-25

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

50 enrolled 6 charts

Brain Neoplasms, Meningioma, Neurofibromatosis 1, Neurofibromatosis 2, Central Nervous System Neoplasms, Neurofibromatoses, Hemangioblastoma

NCT00004437 2015-03-25

Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2

Mental Disorders, Neurologic Manifestations, Neuroma, Acoustic, Neurofibromatosis 2, Neurofibromatoses, Genetic Diseases, Inborn, Hearing Loss, Rare Diseases

NCT01412892 2014-11-14

NFitor

30 enrolled