Clinical Trials Browser

Interventional × Neurofibromatoses × Clear all

NCT02211768 2026-05-22

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Phase 1 Completed

Neurofibromatoses, Neurofibrosarcoma

NCT07102394 2026-05-08

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Phase 1 Recruiting

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT03962543 2026-05-06

ReNeu

Phase 2 Active not recruiting

114 enrolled 25 charts 1 FDA

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT06934928 2026-03-05

Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs)

Phase NA Suspended

Neurofibromatosis 1, Neurofibromatoses

NCT07233408 2026-02-27

Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy

Phase NA Recruiting

Neurofibromatosis 1, Neurofibromatoses

NCT03873610 2025-12-26

Resiliency Training in Adolescents With NF1 and NF2

Phase NA Active not recruiting

Neurofibromatoses

NCT03406208 2025-12-24

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

Phase NA Completed

Schwannomatosis, Behavior, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT06961565 2025-12-04

PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas

Phase 1 Recruiting

Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT07237100 2025-11-19

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Phase 2 Recruiting

CNSDermatologic

Melanoma, Neurofibromatoses

NCT06262113 2025-10-03

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Phase NA Recruiting

Neurofibromatosis 1, Neurofibromatoses

NCT03231306 2025-05-02

NF108-BINI

Phase 2 Completed

45 enrolled 8 charts

Neurofibroma, Neurofibromatosis 1, Peripheral Nervous System Neoplasms, Neurofibromatoses, Neurofibroma, Plexiform

NCT05196854 2025-02-24

Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

Phase NA Completed

Hypertension, Neurofibromatosis 1, Neurofibromatoses

NCT05438290 2024-05-06

DPCP to Treat Cutaneous Neurofibromas Associated With NF1

Phase 1 Completed

Neurofibromatosis 1, Neurofibromatoses

NCT05011019 2024-03-21

A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis

Phase 1/2 Terminated

Neurofibromatoses, Neurofibrosarcoma

NCT04474678 2024-01-09

Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")

Phase NA Completed

CNSOther hematologic neoplasmSarcoma

Brain Neoplasms, Hematologic Diseases, Leukemia, Neuroblastoma, Sarcoma, Neurofibromatoses

NCT05377008 2023-09-22

OPTIMAL-SSI

Phase NA Completed

Neurofibromatosis 1, Neurofibromatoses

NCT02101736 2023-05-24

NF105-CABO

Phase 2 Completed

45 enrolled 10 charts

Neurofibromatoses, Neurofibroma, Plexiform

NCT05779527 2023-03-22

Mindful Parenting - A Single Case Experimental Design Study

Phase NA Unknown

Alopecia, Cleft Lip, Skin Diseases, Neurofibromatoses

NCT04461886 2022-05-24

A Long-term Study of NPC-12G Gel in Neurofibromatosis Type I

Phase 3 Terminated

Neurofibromatoses

NCT05107037 2021-11-04

A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of TQ-B3234 in Patients With Type I Neurofibromatosis

Phase 1 Unknown

Neurofibromatoses

NCT01682811 2021-06-18

Phase I Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)

Phase 1 Completed

20 enrolled 11 charts

Neurofibromatoses

NCT03513757 2020-02-21

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Phase 4 Completed

40 enrolled 15 charts

Abdominal Neoplasms, Epilepsy, Headache, Hydrocephalus, Neoplasms, Neurofibromatoses

NCT01633008 2019-09-30

Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic Pain

Phase EARLY_PHASE1 Completed

Depression, Neurofibromatoses

NCT00911248 2019-04-12

PTC299 for Treatment of Neurofibromatosis Type 2

Phase 2 Terminated

Neurofibromatosis 2, Neurofibromatoses

NCT02387177 2018-08-17

Resiliency Training for Adolescent Neurofibromatosis Patients Via Videoconferencing With Skype

Phase NA Completed

Neurofibromatoses

NCT00021541 2018-04-17

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

Phase 2 Completed

62 enrolled 13 charts

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT01402817 2018-03-14

Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas

Phase 2 Terminated

19 enrolled 8 charts

Neurofibromatoses, Neurofibroma, Plexiform

NCT01140360 2017-07-02

0908-09

Phase 1/2 Completed

21 enrolled 8 charts

Neurofibroma, Neurofibromatoses

NCT01275586 2017-04-12

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Phase EARLY_PHASE1 Completed

6 enrolled 7 charts

Neurofibroma, Neurofibromatoses, Neurofibroma, Plexiform

NCT02298270 2016-06-23

Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype

Phase NA Completed

Schwannomatosis, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT01673009 2016-04-06

Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Phase 2 Completed

36 enrolled 8 charts

Neurofibromatoses

NCT00589784 2016-01-25

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Phase 2 Completed

50 enrolled 6 charts

Brain Neoplasms, Meningioma, Neurofibromatosis 1, Neurofibromatosis 2, Central Nervous System Neoplasms, Neurofibromatoses, Hemangioblastoma

NCT00004437 2015-03-25

Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2

Phase 2 Completed

Mental Disorders, Neurologic Manifestations, Neuroma, Acoustic, Neurofibromatosis 2, Neurofibromatoses, Genetic Diseases, Inborn, Hearing Loss, Rare Diseases

NCT01412892 2014-11-14

NFitor

Phase 2 Completed

Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT00427583 2012-08-07

Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors

Phase 2/3 Terminated

Neurofibromatoses, Nerve Sheath Neoplasms, Neurofibrosarcoma

NCT00754780 2012-03-19

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Phase 2 Completed

Neurofibromatoses, Neurofibroma, Plexiform

NCT01031901 2012-02-27

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

Phase 1 Completed

Neurofibroma, Tuberous Sclerosis, Neurofibromatoses, Angiofibroma