Clinical Trials

Phase EARLY_PHASE1 Active not recruiting

90 enrolled

Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT04514029 2026-01-08

Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel

37 enrolled

Lymphoma, Neurotoxicity Syndromes

NCT07320950 2026-01-06

Neuroprotective Effect of Neurotropin on Chronic OXA-induced Neurotoxicity in Stage II and Stage III CRC Patients

333 enrolled

Phase 1 Active not recruiting

Colorectal Neoplasms, Neurotoxicity Syndromes

NCT03696784 2025-12-08

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

19 enrolled

Phase NA Active not recruiting

Cytokine Release Syndrome, Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, B-Cell, Neurotoxicity Syndromes

NCT05025826 2025-12-02

PROPERTY

110 enrolled

Stomach Neoplasms, Neurotoxicity Syndromes

NCT04150913 2025-11-25

A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

15 enrolled 17 charts

Cytokine Release Syndrome, Lymphoma, Non-Hodgkin, Neurotoxicity Syndromes

NCT00727922 2025-11-20

MnDPDP-K04

23 enrolled

Neoplasms, Neurotoxicity Syndromes

NCT04583124 2025-11-18

ATENTO

Phase NA Completed

42 enrolled

Phase 3 Active not recruiting

Breast Neoplasms, Neurotoxicity Syndromes

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

540 enrolled

Phase 3 Enrolling by invitation

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT06950190 2025-08-12

(ECCPC)

100 enrolled

Chemotherapy-Related Cognitive Impairment, Neurotoxicity Syndromes, Cognitive Dysfunction

NCT06551051 2024-09-19

ADC-induced Neurotoxicity Treated With Duloxetine

Phase 2 Recruiting

37 enrolled

Neurotoxicity Syndromes

NCT05510596 2024-08-09

MR-ICANS

Phase NA Completed

25 enrolled

Cytokine Release Syndrome, Lymphoma, B-Cell, Neurotoxicity Syndromes

NCT01399372 2023-07-20

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

91 enrolled 17 charts

Lymphoma, Radiation Injuries, Neurotoxicity Syndromes

NCT05798884 2023-04-05

Electro-acupuncture for the Prevention and Treatment of Oxaliplatin-induced Neurotoxicity in Colorectal Cancer Patients

Phase NA Unknown

150 enrolled

Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00660842 2023-03-24

MITO-7

Phase 3 Unknown

800 enrolled

Gynecologic

Ovarian Neoplasms, Neurotoxicity Syndromes

NCT01099449 2022-11-03

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

362 enrolled 17 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

194 enrolled 11 charts

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT05494320 2022-08-09

the Effect of ABCC2 Genetic Polymorphism on Neurotoxicity in Gastrointestinal Cancer Patients Receiving Oxaliplatin

Unknown

120 enrolled

Gastrointestinal Neoplasms, Neurotoxicity Syndromes

NCT00039780 2022-07-13

Evaluation of BNP7787 for the Prevention of Neurotoxicity in Metastatic Breast Cancer Patients Receiving Weekly Paclitaxel

764 enrolled

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Paresthesia, Neurotoxicity Syndromes

NCT00792142 2021-08-19

Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma

45 enrolled 8 charts

Plasma cell

Multiple Myeloma, Neurotoxicity Syndromes, Neoplasms, Plasma Cell

NCT01381718 2021-08-13

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

112 enrolled 16 charts

Fatigue, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00369564 2021-08-11

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

GenitourinaryLymphoidOther hematologic neoplasmSarcoma

250 enrolled 10 charts

Burkitt Lymphoma, Kidney Neoplasms, Leukemia, Lymphoma, Wilms Tumor, Peripheral Nervous System Diseases, Sarcoma, Lymphoma, Large B-Cell, Diffuse, Neurotoxicity Syndromes, Dendritic Cell Sarcoma, Interdigitating

NCT02864030 2021-03-04

PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment

Phase 4 Completed

200 enrolled

Breast Neoplasms, Neurotoxicity Syndromes, Drug-Related Side Effects and Adverse Reactions

NCT01913093 2020-10-08

NPG

LymphoidOther hematologic neoplasm

204 enrolled

Leukemia, Neurotoxicity Syndromes, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02890030 2020-04-08

The Platinum Study Comparison Group

102 enrolled

Genitourinary

Ototoxicity, Testicular Neoplasms, Neurotoxicity Syndromes

NCT01293851 2019-12-05

Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage

Terminated

3 enrolled

Neoplasms, Neuralgia, Neurotoxicity Syndromes

NCT01418495 2019-10-01

Pharmacokinetics of Ch14.18 in Younger Patients With High-Risk Neuroblastoma

12 enrolled

Neuroblastoma, Pain, Neurotoxicity Syndromes

NCT00001807 2019-04-24

(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy

50 enrolled

Phase EARLY_PHASE1 Completed

Brain Neoplasms, Neurotoxicity Syndromes

NCT00807768 2019-03-20

Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer

Phase 3 Unknown

601 enrolled 13 charts

Other

Fatigue, Obesity, Neurotoxicity Syndromes

NCT01372787 2019-03-12

Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer

Unknown

103 enrolled

Gynecologic

Anxiety Disorders, Fallopian Tube Neoplasms, Fatigue, Nausea, Ovarian Neoplasms, Vomiting, Neurotoxicity Syndromes

NCT00452868 2018-09-07

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

14 enrolled 7 charts

Familial ependymoma, Astrocytoma, Medulloblastoma, Radiation Injuries, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neurotoxicity Syndromes, Optic Nerve Glioma

NCT00068445 2018-05-04

Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

131 enrolled 14 charts

Pain, Neurotoxicity Syndromes

NCT02486198 2018-02-05

Monosialotetrahexosylganglioside for Treatment of Oxaliplatin Induced Neurotoxicity in Gastrointestinal Cancer

145 enrolled

Gastrointestinal Neoplasms, Neurotoxicity Syndromes

NCT01279681 2017-12-08

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Phase 3 Terminated

32 enrolled 14 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00755313 2017-11-24

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

81 enrolled

Breast Neoplasms, Fatigue, Neurotoxicity Syndromes

NCT01050075 2017-11-06

Acupuncture in Treating Nerve Pain in Patients With Stage I, Stage II, or Stage III Breast Cancer Who Are Receiving Paclitaxel

Phase NA Terminated

7 enrolled

Breast Neoplasms, Breast Neoplasms, Male, Neurotoxicity Syndromes

NCT03330964 2017-11-06

Clinical Trial of Electroacupuncture Stimulation on Prevention and Treatment of Oxaliplatin Neurotoxicity

Phase NA Unknown

120 enrolled

Gastrointestinal Neoplasms, Neurotoxicity Syndromes

NCT00754767 2017-09-11

L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancer

Phase 4 Terminated

2 enrolled 3 charts

Breast Neoplasms, Neurotoxicity Syndromes

NCT00516503 2017-08-24

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer