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Phase

Phase EARLY_PHASE1 1Phase 2 1Phase 1/2 1

Status

Completed 2Withdrawn 1

Sponsor Class

OTHER 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

Lymphoid 3Other 1CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 250Leukemia 186Lymphoma 137Leukemia, Myeloid, Acute 103Burkitt Lymphoma 90Myelodysplastic Syndromes 79Lymphoma, Non-Hodgkin 65Breast Neoplasms 60Lymphoma, Large B-Cell, Diffuse 59Leukemia, Lymphocytic, Chronic, B-Cell 49Lymphoma, Mantle-Cell 47Hodgkin Disease 47Graft vs Host Disease 46Lymphoma, Follicular 45Leukemia, Myeloid, Accelerated Phase 45Multiple Myeloma 39Leukemia, Myeloid, Chronic-Phase 39Congenital Abnormalities 39Myeloproliferative Disorders 38Blast Crisis 38Leukemia, Myelomonocytic, Chronic 37Leukemia, Biphenotypic, Acute 35Recurrence 34Lymphoma, Large-Cell, Immunoblastic 33Lymphoma, B-Cell, Marginal Zone 31Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Osteosarcoma 29Primary Myelofibrosis 27Neoplasms, Plasma Cell 25Leukemia, Myelogenous, Chronic, BCR-ABL Positive 25

Interventions

Paclitaxel 8Oxaliplatin 6Carboplatin 5Vincristine 4Radiotherapy 4Mental Status and Dementia Tests 4Leucovorin 4Amifostine 4Taxes 3Sodium Chloride 3Procarbazine 3Methotrexate 3Magnetic Resonance Spectroscopy 3Fluorouracil 3Cytarabine 3Cyclophosphamide 3Cisplatin 3xaliproden 2glucarpidase 2Surveys and Questionnaires 2Rituximab 2Radiotherapy, Intensity-Modulated 2Radiotherapy, Conformal 2Psychiatric Rehabilitation 2Prednisolone 2Magnesium Sulfate 2Folfox protocol 2Duloxetine Hydrochloride 2Doxorubicin 2Dexamethasone 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Neurotoxicity Syndromes × Methotrexate × Clear all
NCT01399372 2023-07-20

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Radiation Therapy Oncology Group

Phase 2 Completed
91 enrolled 17 charts
Lymphoid

Lymphoma, Radiation Injuries, Neurotoxicity Syndromes

NCT00727831 2014-01-27

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

University College, London

Phase 1/2 Completed
4 enrolled
LymphoidOther

Lymphoma, Lymphoma, Large B-Cell, Diffuse, Neurotoxicity Syndromes, Mucositis

NCT00734773 2012-05-18

Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Northwestern University

Phase EARLY_PHASE1 Withdrawn
CNSLymphoid

Lymphoma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

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