Clinical Trials

158 enrolled

Neoplasms, Respiration Disorders, Pleural Effusion, Malignant

NCT05461430 2026-04-13

TraveraRTGx

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

72 enrolled

Anus Neoplasms, Appendiceal Neoplasms, Ascites, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Stomach Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Small Cell, Carcinoma, Pancreatic Ductal, Gastrointestinal Stromal Tumors

NCT02122185 2026-03-27

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

111 enrolled 15 charts

GynecologicThoracic

Carcinoma, Ovarian Epithelial, Brenner Tumor, Fallopian Tube Neoplasms, Pleural Effusion, Malignant

NCT06436807 2026-03-12

PMCF Study of the CE-marked Drainova® ArgentiC Catheter

169 enrolled

Ascites, Pleural Effusion, Pleural Effusion, Malignant

NCT02649894 2025-12-11

SWIFT

119 enrolled 16 charts

Pleural Effusion, Malignant

NCT02227732 2025-11-26

A Pilot Study Evaluating the Safety and Effectiveness of a New Pleural Catheter for the Medical Management of Symptomatic, Recurrent, Malignant Pleural Effusions

10 enrolled

Pleural Effusion, Malignant

NCT03235999 2025-10-03

The Experiences of Patients Living With Malignant Pleural Effusions

10 enrolled

Pleural Effusion, Malignant

NCT06657638 2025-05-29

Cytological Examination of Malignant Pleural Effusion in Breast Cancer

50 enrolled

BreastThoracic

Breast Neoplasms, Pleural Effusion, Malignant

NCT06744946 2024-12-20

Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural Effusion

Phase 4 Completed

60 enrolled

Pleural Effusion, Malignant

NCT06729931 2024-12-12

Quantitative C-Reactive Protein for Differentiating Tuberculous and Malignant Pleural Effusion: a Cross-Sectional Study

81 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT03414905 2024-02-20

Management of Malignant Pleural Effusions Using an Indwelling Tunneled Pleural Catheter and Non-Vacuum Collection System

40 enrolled

Pleural Effusion, Malignant

NCT02517749 2023-11-24

OPTIMUM

142 enrolled

Pleural Effusion, Malignant

NCT00993655 2023-08-28

Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer

275 enrolled 13 charts

GynecologicThoracic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pleural Effusion, Malignant

NCT01997190 2023-08-25

MpeTK01

BreastGynecologicOther solid neoplasmThoracic

19 enrolled

Breast Neoplasms, Lung Neoplasms, Mesothelioma, Ovarian Neoplasms, Pleural Effusion, Malignant

NCT00002872 2023-06-22

Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions

480 enrolled

Neoplasm Metastasis, Pleural Effusion, Malignant

NCT05372055 2023-06-09

MY-IPC

18 enrolled

Pleural Effusion, Malignant

NCT04264325 2023-05-10

ADD-Echo

15 enrolled

OtherThoracic

Dyspnea, Lung Neoplasms, Pleural Effusion, Malignant

NCT04749602 2023-03-08

Intrapleural Instillation of the Nivolumab in Cancer Patients With Pleural Effusion.

26 enrolled

Pleural Effusion, Malignant

NCT02583282 2022-10-06

A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion

100 enrolled

Pleural Effusion, Malignant

NCT00637676 2022-09-02

Tunneled Pleural Catheter in Partially Entrapped Lung

50 enrolled

Pleural Effusion, Malignant

NCT04235998 2022-05-11

Value of Additional Upfront Systematic Lung Ultrasound in the Workup of Patients With Unilateral Pleural Effusion

57 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT04123886 2022-05-06

A Phase I Study Evaluating SCB-313(Recombinant Human TRAIL-Trimer Fusion Protein) for the Treatment of Malignant Pleural Effusion

14 enrolled

Pleural Effusion, Malignant

NCT03869697 2022-02-02

Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural Effusions

5 enrolled

Pleural Effusion, Malignant

NCT01302808 2021-01-20

Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

17 enrolled 12 charts

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Malignant

NCT03270215 2020-12-17

The Added Value of CT Scanning in Patients With an Unilateral Pleural Effusion

232 enrolled

Hypersensitivity, Pleural Effusion, Malignant

NCT03272997 2020-12-17

The Value of PET-CT in Pleural Effusions

112 enrolled

Hypersensitivity, Pleural Effusion, Malignant

NCT01999985 2020-11-27

Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)

25 enrolled 10 charts

Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Pleural Diseases, Pleural Effusion, Pleural Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Pleural Effusion, Malignant

NCT03597828 2020-06-30

Respiratory Function of Dexmedetomidine in Patients Undergoing Pleuroscopy

60 enrolled

Bronchiolitis Obliterans Syndrome, Pleural Diseases, Pleural Effusion, Pleural Effusion, Malignant

NCT00066404 2020-05-13

Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions

BreastDermatologicGastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymoma, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Pleural Effusion, Malignant, Endometrial Neoplasms, Breast Neoplasms, Male, Gestational Trophoblastic Disease, Small Cell Lung Carcinoma

NCT02674243 2020-01-23

Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion

60 enrolled

Pleural Effusion, Malignant

NCT00126581 2019-08-07

Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer

188 enrolled 16 charts

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Pleural Effusion, Malignant

NCT02054052 2019-03-29

Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer

22 enrolled

Carcinoma, Non-Small-Cell Lung, Pericardial Effusion, Pleural Effusion, Malignant

NCT03394105 2019-03-08

Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer

4 enrolled

Pleural Effusion, Malignant

NCT03276715 2018-10-11

Prognostic Factors on Malignant Pleural Effusion

233 enrolled

Lung Neoplasms, Pleural Effusion, Malignant

NCT02625675 2018-01-09

Using Thoracic Ultrasound to Predict Pleurodesis Success in Malignant Pleural Effusions: a Pilot Study

18 enrolled

Pleural Effusion, Malignant

NCT00528645 2017-12-07

AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer

23 enrolled 7 charts

Pleural Effusion, Malignant, Small Cell Lung Carcinoma

NCT00188474 2017-05-04

A Quality of Life Study re Management of Malignant Pleural Effusions

149 enrolled

Pleural Effusion, Malignant

NCT00408460 2017-04-25

Imatinib Mesylate and Paclitaxel in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

34 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT00215930 2017-03-23

The 'MADe IT' Clinical Trial: Molecular Analyses Directed Individualized Therapy for Advanced Non-Small Cell Lung Cancer

53 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT00231465 2017-03-03

Phase II Study of Docetaxel + ZD1839 in Elderly Patients With Non-Small Cell Lung Cancer

44 enrolled 7 charts

Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT00508144 2017-02-13

Single Agent Alimta in Poor Performance Status in Non-small Cell Lung Cancer

64 enrolled 5 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pericardial Effusion, Pleural Effusion, Malignant

NCT00564733 2017-02-10

FDG-Labeled PET Scan in Planning Chemotherapy in Treating Patients With Stage IIIB or IV Non-Small Cell Lung Cancer

55 enrolled 7 charts

Carcinoma, Non-Small-Cell Lung, Pleural Effusion, Malignant

NCT00758316 2017-02-10

A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions

120 enrolled

Pleural Effusion, Malignant

NCT00042770 2016-07-04

Standard Chest Tube Compared With a Small Catheter in Treating Malignant Pleural Effusion in Patients With Cancer

67 enrolled

Neoplasm Metastasis, Pleural Effusion, Malignant

NCT00002622 2016-06-28

Talc in Treating Patients With Malignant Pleural Effusion

501 enrolled

Neoplasm Metastasis, Pleural Effusion, Malignant

NCT01117740 2016-04-11

Pleural Catheters Versus Thoracoscopic Pleurodesis

445 enrolled

Lung Neoplasms, Pleural Effusion, Malignant

NCT00533585 2016-02-10

BAY 43-9006 in Previously Untreated Patients With Non-Small Cell Lung Cancer (NSCLC)

23 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion, Malignant

NCT00896285 2015-07-20

TIME-1

4 enrolled

Neoplasms, Pleural Effusion, Pleural Effusion, Malignant

NCT00019825 2015-04-29

Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura