Clinical Trials Browser

Pleuropulmonary blastoma × Clear all

Pleuropulmonary blastoma, Thyroid Neoplasms

NCT06647953 2026-05-05

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Phase 3 Recruiting

110 enrolled

Pleuropulmonary blastoma

NCT07072143 2025-07-18

PARTNER

Recruiting

6,250 enrolled

CNSDermatologicGastrointestinalHead & NeckOther solid neoplasmSarcomaThoracic

Pleuropulmonary blastoma, Nasopharyngeal Carcinoma, Adrenal Cortex Neoplasms, Melanoma, Mesothelioma, Pancreatic Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Esthesioneuroblastoma, Olfactory, Gastrointestinal Stromal Tumors

NCT03382158 2025-01-30

International PPB/DICER1 Registry

Recruiting

3,400 enrolled

CNSEndocrineGenitourinaryHead & NeckSarcoma

Pleuropulmonary blastoma, Disease, Goiter, Nodular, Wilms Tumor, Neuroblastoma, Pinealoma, Pituitary Neoplasms, Thyroid Neoplasms, Thyroid Nodule, Rhabdomyosarcoma, Embryonal, Sertoli-Leydig Cell Tumor, Sex Cord-Gonadal Stromal Tumors

NCT00565903 2023-03-01

PPB

Completed

1,247 enrolled

EndocrineGenitourinarySarcoma

Pleuropulmonary blastoma, Goiter, Wilms Tumor, Pinealoma, Pituitary Neoplasms, Sarcoma, Neuroectodermal Tumors, Primitive, Sertoli-Leydig Cell Tumor

NCT02452554 2022-01-13

Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

Phase 2 Completed

62 enrolled 15 charts

CNSGenitourinarySarcoma

Pleuropulmonary blastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Synovial, Neurofibrosarcoma

NCT03044769 2020-04-16

CLADatabase

Unknown

100 enrolled

Pleuropulmonary blastoma, Cystic Adenomatoid Malformation of Lung, Congenital

NCT01353300 2016-07-11

Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing Cancer

Completed

31 enrolled

CNSGastrointestinalGenitourinarySarcoma

Pleuropulmonary blastoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma

Clinical Trials

DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study