Announcements Trials
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Phase

Phase 3 1

Status

Recruiting 4Completed 3Unknown 1

Sponsor Class

OTHER 2NIH 1NETWORK 1

Study Type

Observational 3Interventional 1

Sponsor

Cancer Type

Head & Neck 3Sarcoma 2CNS 2Thoracic 1Other solid neoplasm 1Genitourinary 1Gastrointestinal 1Endocrine 1Dermatologic 1

Conditions

Breast Neoplasms 1774Neoplasms 1501Carcinoma, Non-Small-Cell Lung 1043Prostatic Neoplasms 957Colorectal Neoplasms 878Lung Neoplasms 800Pancreatic Neoplasms 572Carcinoma, Hepatocellular 542Leukemia, Myeloid, Acute 541Stomach Neoplasms 512Ovarian Neoplasms 507Neoplasm Metastasis 496Multiple Myeloma 495Recurrence 413Melanoma 386Squamous Cell Carcinoma of Head and Neck 370Brain Neoplasms 362Uterine Cervical Neoplasms 361Head and Neck Neoplasms 355Esophageal Neoplasms 312Precursor Cell Lymphoblastic Leukemia-Lymphoma 310Lymphoma 305Endometrial Neoplasms 304Triple Negative Breast Neoplasms 299Glioblastoma 298Rectal Neoplasms 280Urinary Bladder Neoplasms 264Sarcoma 264Hematologic Neoplasms 264Colonic Neoplasms 254

Interventions

Watchful Waiting 1Vincristine 1Topotecan 1Specimen Handling 1Razoxane 1Observation 1Magnetic Resonance Spectroscopy 1Ifosfamide 1High-Energy Shock Waves 1Doxorubicin 1Dexrazoxane 1Dactinomycin 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Recruiting × Pleuropulmonary blastoma × Clear all
NCT01247597 2026-06-03

DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

National Institutes of Health Clinical Center (CC)

Recruiting
1,500 enrolled
Head & Neck

Pleuropulmonary blastoma, Thyroid Neoplasms

NCT06647953 2026-05-05

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Children's Oncology Group

Phase 3 Recruiting
110 enrolled

Pleuropulmonary blastoma

NCT07072143 2025-07-18

PARTNER

Azienda Ospedaliera di Padova

Recruiting
6,250 enrolled
CNSDermatologicGastrointestinalHead & NeckOther solid neoplasmSarcomaThoracic

Pleuropulmonary blastoma, Nasopharyngeal Carcinoma, Adrenal Cortex Neoplasms, Melanoma, Mesothelioma, Pancreatic Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Esthesioneuroblastoma, Olfactory, Gastrointestinal Stromal Tumors

NCT03382158 2025-01-30

International PPB/DICER1 Registry

Children's Hospitals and Clinics of Minnesota

Recruiting
3,400 enrolled
CNSEndocrineGenitourinaryHead & NeckSarcoma

Pleuropulmonary blastoma, Disease, Goiter, Nodular, Wilms Tumor, Neuroblastoma, Pinealoma, Pituitary Neoplasms, Thyroid Neoplasms, Thyroid Nodule, Rhabdomyosarcoma, Embryonal, Sertoli-Leydig Cell Tumor, Sex Cord-Gonadal Stromal Tumors

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