Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2Recruiting 1No longer available 1Active not recruiting 1

Sponsor Class

NIH 4INDUSTRY 1

Study Type

Observational 2Interventional 2Expanded_access 1

Sponsor

Cancer Type

Head & Neck 1

Conditions

Breast Neoplasms 13138Neoplasms 10481Carcinoma, Non-Small-Cell Lung 6874Prostatic Neoplasms 6268Colorectal Neoplasms 5948Lung Neoplasms 5105Multiple Myeloma 3577Pancreatic Neoplasms 3563Leukemia, Myeloid, Acute 3510Neoplasm Metastasis 3508Carcinoma, Hepatocellular 3273Ovarian Neoplasms 3168Melanoma 3141Stomach Neoplasms 3057Lymphoma 2983Head and Neck Neoplasms 2604Recurrence 2557Precursor Cell Lymphoblastic Leukemia-Lymphoma 2499Leukemia 2362Colonic Neoplasms 2328Brain Neoplasms 2313Lymphoma, Non-Hodgkin 2269Rectal Neoplasms 2192Uterine Cervical Neoplasms 2191Glioblastoma 2016Leukemia, Lymphocytic, Chronic, B-Cell 1992Carcinoma, Renal Cell 1913Squamous Cell Carcinoma of Head and Neck 1880Lymphoma, Follicular 1848Esophageal Neoplasms 1801

Interventions

Miransertib 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Proteus Syndrome × Clear all
NCT00001403 2026-06-05

Study of Proteus Syndrome and Related Congenital Disorders

National Institutes of Health Clinical Center (CC)

Recruiting
1,500 enrolled

Abnormalities, Multiple, Growth Disorders, Proteus Syndrome

NCT04316546 2026-06-05

MK-7075 (Miransertib) in Proteus Syndrome

National Institutes of Health Clinical Center (CC)

Phase 2 Active not recruiting
38 enrolled

Proteus Syndrome

NCT02594215 2022-06-30

Dose Finding Trial of MK-7075 in Children and Adults With Proteus Syndrome

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
6 enrolled

Proteus Syndrome

NCT03317366 2021-08-06

Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies

ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)

No longer available

Congenital Abnormalities, Growth Disorders, Hereditary Sensory and Autonomic Neuropathies, Proteus Syndrome

NCT01369953 2018-07-26

Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants

National Institutes of Health Clinical Center (CC)

Completed
30 enrolled
Head & Neck

Hyperparathyroidism 2, Coronary Artery Disease, Proteus Syndrome, Genetic Diseases, Inborn

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