Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

No longer available 1Completed 1Active not recruiting 1

Sponsor Class

NIH 2INDUSTRY 1

Study Type

Interventional 2Expanded_access 1

Sponsor

Conditions

Proteus Syndrome 3Neoplasms 2Endometrial Neoplasms 2Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Ovarian Neoplasms 1Lymphoma 1Hereditary Sensory and Autonomic Neuropathies 1Growth Disorders 1Congenital Abnormalities 1

Interventions

Miransertib 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Proteus Syndrome × Miransertib × Clear all
NCT04316546 2026-06-05

MK-7075 (Miransertib) in Proteus Syndrome

National Institutes of Health Clinical Center (CC)

Phase 2 Active not recruiting
38 enrolled

Proteus Syndrome

NCT02594215 2022-06-30

Dose Finding Trial of MK-7075 in Children and Adults With Proteus Syndrome

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
6 enrolled

Proteus Syndrome

NCT03317366 2021-08-06

Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies

ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)

No longer available

Congenital Abnormalities, Growth Disorders, Hereditary Sensory and Autonomic Neuropathies, Proteus Syndrome

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