Clinical Trials

Phase NA Active not recruiting

Spinal Cord Neoplasms, Spinal Diseases

NCT03839914 2026-04-29

Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients

76 enrolled

Spinal Cord Neoplasms, Surgical Wound Infection, Wounds and Injuries

NCT07527728 2026-04-14

Postoperative Neurological Recovery and Risk Factor Analysis in Patients With Paralysis Due to Spinal Metastases

Not yet recruiting

150 enrolled

Phase NA Not yet recruiting

Paralysis, Spinal Cord Compression, Spinal Cord Neoplasms

NCT07527884 2026-04-14

The Effect of Radiotherapy After Separation Surgery for Spinal Metastases

130 enrolled

Spinal Cord Neoplasms

NCT04533919 2026-04-06

Validation of Pre-clinical Nano-Based Analgesics in Cells From Human Dorsal Root Ganglia

Withdrawn

Spinal Cord Neoplasms

NCT03398915 2026-03-31

EUROSPIN

Active not recruiting

932 enrolled 8 charts

Intervertebral Disc Displacement, Spinal Cord Neoplasms, Spinal Stenosis, Spondylolisthesis, Discitis, Intervertebral Disc Degeneration

NCT05296889 2026-03-31

CERISE

200 enrolled

Spinal Cord Neoplasms, Spinal Fractures, Intervertebral Disc Degeneration

NCT02851706 2026-03-27

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

Completed

1,214 enrolled

Astrocytoma, Brain Neoplasms, Glioma, Neoplasms, Spinal Cord Neoplasms

NCT07488702 2026-03-27

GTTIR

Active not recruiting

50 enrolled

Spinal Cord Compression, Spinal Cord Neoplasms, Spinal Neoplasms

NCT05170815 2026-03-17

ErYs

760 enrolled

Spinal Cord Neoplasms, Spinal Fractures

NCT07429422 2026-02-24

SBRT Technique Implementation for Spinal Metastases Irradiation

Spinal Cord Neoplasms

NCT05957679 2026-02-12

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

20 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Meningioma, Neurofibroma, Spinal Cord Neoplasms

NCT07354178 2026-01-21

Study of Collagen-Based Thrombin Hemostat for the Control of Bleeding in Spinal Surgery

130 enrolled

Phase 1 Not yet recruiting

Spinal Cord Neoplasms, Spinal Injuries, Spinal Stenosis, Blood Loss, Surgical

NCT06357377 2026-01-14

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

12 enrolled

Choroid Plexus Carcinoma, Glioma, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT07225491 2025-12-19

Spine Oncology Registry

3,000 enrolled

Phase NA Not yet recruiting

Spinal Cord Neoplasms

NCT05396222 2025-12-17

A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine

18 enrolled

Spinal Cord Neoplasms

NCT07224451 2025-11-04

BDF002

20 enrolled

Spinal Cord Neoplasms

NCT04977375 2025-09-03

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

Phase 1/2 Recruiting

10 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT01295944 2025-08-05

Carboplatin and Bevacizumab for Recurrent Ependymoma

35 enrolled 17 charts

Brain Neoplasms, Ependymoma, Neoplasms, Neurologic Manifestations, Spinal Cord Neoplasms

NCT07066475 2025-07-23

DLS

Spinal Cord Neoplasms

NCT04227717 2025-07-18

Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine

9 enrolled

CNSThoracic

Spinal Cord Neoplasms, Spinal Diseases, Thoracic Diseases, Thoracic Neoplasms

NCT07056023 2025-07-09

EURJMT

Meningioma, Spinal Cord Neoplasms

NCT03173950 2025-06-29

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

133 enrolled

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningioma, Pinealoma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms

NCT05023772 2025-06-26

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

60 enrolled

Agnosia, Neoplasm Metastasis, Spinal Cord Compression, Spinal Cord Diseases, Spinal Cord Neoplasms, Epidural Neoplasms

NCT03956537 2025-06-13

PMCF Neo Pedicle Screw and Cage Systems

Active not recruiting

150 enrolled

Spinal Cord Neoplasms, Spinal Stenosis, Spondylolisthesis, Wounds and Injuries, Intervertebral Disc Degeneration

NCT04743310 2025-06-13

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

50 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Neuroma, Acoustic, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT03593330 2025-05-02

TCP

Phase NA Terminated

242 enrolled

Aneurysm, Brain Diseases, Brain Neoplasms, Hydrocephalus, Spinal Cord Neoplasms, Spinal Curvatures, Spinal Diseases, Spinal Stenosis, Trigeminal Neuralgia, Spinal Fractures

NCT06869746 2025-03-19

SSTR

250 enrolled

Spinal Cord Neoplasms

NCT06161974 2025-02-21

Study of Olutasidenib and Temozolomide in HGG

Phase 2 Recruiting

60 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Spinal Cord Neoplasms

NCT04525014 2024-10-31

PIRATE

Phase 1 Terminated

2 enrolled

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT06613295 2024-09-25

SABR-MESCC

128 enrolled

Spinal Cord Neoplasms, Spinal Neoplasms

NCT06587022 2024-09-19

ST-SBRT

500 enrolled

Spinal Cord Neoplasms

NCT03052738 2024-08-29

Medical Marijuana in the Pediatric Central Nervous System Tumor Population

Completed

19 enrolled

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT06042946 2024-08-21

Microsurgical Resection of Intramedullary Spinal Cord Metastases

60 enrolled

Spinal Cord Neoplasms

NCT02790294 2024-05-14

Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal

8 enrolled

Spinal Cord Neoplasms

NCT04219969 2024-05-09

FDG PET-MRI for the Diagnosis of Spinal Cord Lesions

11 enrolled

Spinal Cord Neoplasms

NCT06395831 2024-05-02

Assessment of Quality of Life and Independence, as Well as Received Social Support for Spinal Cancer.

Unknown

Spinal Cord Neoplasms

NCT01236560 2024-02-20

Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma

Phase 2/3 Completed

101 enrolled 15 charts

Astrocytoma, Spinal Cord Neoplasms

NCT06120426 2023-11-13

En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

182 enrolled

CNSSarcoma

Bone Neoplasms, Spinal Cord Neoplasms

NCT00788125 2023-07-14

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Phase 1/2 Terminated

7 enrolled 9 charts

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Burkitt Lymphoma, Carcinoma, Renal Cell, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Spinal Cord Neoplasms, Teratoma, Testicular Neoplasms, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Nephroma, Mesoblastic, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT05096468 2023-07-06

Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.

Phase 2/3 Completed

90 enrolled

Pain, Postoperative, Spinal Cord Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT05678608 2023-01-10

Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Phase NA Unknown

20 enrolled

Spinal Cord Neoplasms

NCT05631002 2022-11-30

Chemical Shift Encoding-based Water-fat Magnetic Resonance Imaging in Spinal Tumors

Unknown

150 enrolled

CNSSarcoma

Bone Neoplasms, Spinal Cord Neoplasms

NCT04578691 2022-11-10

Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery

55 enrolled

Spinal Cord Neoplasms, Spinal Injuries

NCT02085941 2022-08-15

Image-guided Cryoablation of Head, Neck and Spine Tumors