Clinical Trials

1,214 enrolled

Astrocytoma, Brain Neoplasms, Glioma, Neoplasms, Spinal Cord Neoplasms

NCT07354178 2026-01-21

Study of Collagen-Based Thrombin Hemostat for the Control of Bleeding in Spinal Surgery

130 enrolled

Spinal Cord Neoplasms, Spinal Injuries, Spinal Stenosis, Blood Loss, Surgical

NCT01295944 2025-08-05

Carboplatin and Bevacizumab for Recurrent Ependymoma

35 enrolled 17 charts

Brain Neoplasms, Ependymoma, Neoplasms, Neurologic Manifestations, Spinal Cord Neoplasms

NCT04227717 2025-07-18

Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine

9 enrolled

CNSThoracic

Spinal Cord Neoplasms, Spinal Diseases, Thoracic Diseases, Thoracic Neoplasms

NCT03173950 2025-06-29

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

133 enrolled

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningioma, Pinealoma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms

NCT04743310 2025-06-13

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

50 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Neuroma, Acoustic, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT03052738 2024-08-29

Medical Marijuana in the Pediatric Central Nervous System Tumor Population

19 enrolled

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT02790294 2024-05-14

Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal

8 enrolled

Spinal Cord Neoplasms

NCT04219969 2024-05-09

FDG PET-MRI for the Diagnosis of Spinal Cord Lesions

11 enrolled

Spinal Cord Neoplasms

NCT01236560 2024-02-20

Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma

Phase 2/3 Completed

101 enrolled 15 charts

Astrocytoma, Spinal Cord Neoplasms

NCT05096468 2023-07-06

Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.

Phase 2/3 Completed

90 enrolled

Pain, Postoperative, Spinal Cord Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT04578691 2022-11-10

Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery

55 enrolled

Spinal Cord Neoplasms, Spinal Injuries

NCT02085941 2022-08-15

Image-guided Cryoablation of Head, Neck and Spine Tumors

30 enrolled 10 charts

CNSHead & Neck

Head and Neck Neoplasms, Spinal Cord Neoplasms

NCT02013297 2022-03-08

SBRT

61 enrolled

CNSThoracic

Brain Neoplasms, Ependymoma, Lung Neoplasms, Spinal Cord Neoplasms

NCT04952818 2021-07-07

The Value of Preoperative Diagnosis and Prognostic Prediction Based on Radiomics of Giant Cell Tumor of Spine

100 enrolled

Recurrence, Spinal Cord Neoplasms, Giant Cell Tumor of Bone

NCT01637766 2020-08-03

SIAC

12 enrolled

Spinal Cord Compression, Spinal Cord Neoplasms, Spinal Diseases

NCT04331431 2020-04-02

Outcomes of the Intradural Extramedullary Tumors Resection

24 enrolled

Spinal Cord Neoplasms

NCT00826241 2019-03-22

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

58 enrolled 11 charts

Brain Neoplasms, Ependymoma, Spinal Cord Neoplasms

NCT03050203 2019-01-28

kit

37 enrolled 5 charts

Bone Diseases, Spinal Cord Neoplasms, Osteoarthritis, Spine

NCT02613390 2019-01-10

Safety Evaluation of Intra-Operative MRI-Based Guidance for Laser Ablation of Epidural Metastasis

11 enrolled

Phase EARLY_PHASE1 Completed

Spinal Cord Neoplasms

NCT00452868 2018-09-07

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

14 enrolled 7 charts

Familial ependymoma, Astrocytoma, Medulloblastoma, Radiation Injuries, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neurotoxicity Syndromes, Optic Nerve Glioma

NCT03585699 2018-07-19

Percutaneous Fluoroscopic vs CT Guided Core Needle Biopsy for Spinal Infection and Tumor

60 enrolled

Spinal Cord Neoplasms, Discitis

NCT00077207 2018-05-16

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

66 enrolled 13 charts

Brain Neoplasms, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00276640 2018-04-20

SIOP-LGG-2004

3,417 enrolled

Astrocytoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00381797 2017-11-28

Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma

97 enrolled 35 charts

Familial ependymoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms

NCT00326664 2016-03-07

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

55 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00124657 2015-12-04

Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma

Phase 1/2 Completed

62 enrolled 15 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT02252185 2015-12-03

A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery

106 enrolled

Spinal Cord Neoplasms, Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Intervertebral Disc Degeneration

NCT02494622 2015-07-10

Alternative Treatment of Giant Spinal Schwannomas

18 enrolled

Spinal Cord Neoplasms

NCT01158300 2015-05-04

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

28 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Meningioma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00107458 2014-08-07

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

26 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00946335 2014-07-09

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

31 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00003141 2014-03-28

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

94 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Neuroblastoma, Sarcoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor

NCT00028795 2014-02-21

Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma

170 enrolled

Astrocytoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00066248 2014-02-03

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

CNSLymphoidMyeloidOther hematologic neoplasmSarcoma

70 enrolled

Familial ependymoma, Astrocytoma, Blast Crisis, Brain Neoplasms, Burkitt Lymphoma, Cachexia, Leukemia, Leukemia, Hairy Cell, Lymphoma, Medulloblastoma, Myelodysplastic Syndromes, Oligodendroglioma, Recurrence, Spinal Cord Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myelomonocytic, Chronic, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating

NCT01076530 2013-05-03

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

27 enrolled

CNSEndocrine

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Paraganglioma, Extra-Adrenal, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00053963 2013-01-16

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

CNSLymphoidOther hematologic neoplasm

30 enrolled

Familial ependymoma, Astrocytoma, Blast Crisis, Medulloblastoma, Spinal Cord Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00363272 2013-01-16

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

30 enrolled

CNSLymphoidSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Dendritic Cell Sarcoma, Interdigitating

NCT00430872 2012-08-01

Development of the MDASI-Spine Tumor Module

128 enrolled

Spinal Cord Neoplasms

NCT00631670 2012-02-03

Stereotactic Body Radiation Therapy (SBRT) for Tumors Near the Spinal Cord

21 enrolled 8 charts

Spinal Cord Neoplasms

NCT00015899 2009-10-14

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

53 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00001417 2008-03-04

Direct Injection of Alcohol for the Treatment of Spinal Tumors

30 enrolled