Clinical Trials

Brain Neoplasms, Glioma, Neoplasms, Spinal Cord Neoplasms

NCT01624220 2026-05-12

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

41 enrolled 8 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasms, Unknown Primary, Prostatic Neoplasms, Sarcoma, Spinal Cord Neoplasms, Thyroid Neoplasms

NCT03839914 2026-04-29

Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients

Phase NA Active not recruiting

76 enrolled

Phase NA Not yet recruiting

Spinal Cord Neoplasms, Surgical Wound Infection, Wounds and Injuries

NCT07527884 2026-04-14

The Effect of Radiotherapy After Separation Surgery for Spinal Metastases

130 enrolled

Spinal Cord Neoplasms

NCT07429422 2026-02-24

SBRT Technique Implementation for Spinal Metastases Irradiation

100 enrolled

Spinal Cord Neoplasms

NCT05957679 2026-02-12

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

20 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Meningioma, Neurofibroma, Spinal Cord Neoplasms

NCT07354178 2026-01-21

Study of Collagen-Based Thrombin Hemostat for the Control of Bleeding in Spinal Surgery

130 enrolled

Phase 1 Not yet recruiting

Spinal Cord Neoplasms, Spinal Injuries, Spinal Stenosis, Blood Loss, Surgical

NCT06357377 2026-01-14

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

12 enrolled

Phase NA Not yet recruiting

Choroid Plexus Carcinoma, Glioma, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT05396222 2025-12-17

A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine

18 enrolled

Spinal Cord Neoplasms

NCT07224451 2025-11-04

BDF002

20 enrolled

Spinal Cord Neoplasms

NCT04977375 2025-09-03

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

Phase 1/2 Recruiting

10 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT01295944 2025-08-05

Carboplatin and Bevacizumab for Recurrent Ependymoma

35 enrolled 17 charts

Brain Neoplasms, Ependymoma, Neoplasms, Neurologic Manifestations, Spinal Cord Neoplasms

NCT04227717 2025-07-18

Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine

9 enrolled

CNSThoracic

Spinal Cord Neoplasms, Spinal Diseases, Thoracic Diseases, Thoracic Neoplasms

NCT03173950 2025-06-29

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

133 enrolled

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningioma, Pinealoma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms

NCT05023772 2025-06-26

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

60 enrolled

Agnosia, Neoplasm Metastasis, Spinal Cord Compression, Spinal Cord Diseases, Spinal Cord Neoplasms, Epidural Neoplasms

NCT04743310 2025-06-13

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

50 enrolled

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Neuroma, Acoustic, Pinealoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT03593330 2025-05-02

TCP

Phase NA Terminated

242 enrolled

Aneurysm, Brain Diseases, Brain Neoplasms, Hydrocephalus, Spinal Cord Neoplasms, Spinal Curvatures, Spinal Diseases, Spinal Stenosis, Trigeminal Neuralgia, Spinal Fractures

NCT06161974 2025-02-21

Study of Olutasidenib and Temozolomide in HGG

Phase 2 Recruiting

60 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Spinal Cord Neoplasms

NCT04525014 2024-10-31

PIRATE

Phase 1 Terminated

2 enrolled

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT06613295 2024-09-25

SABR-MESCC

128 enrolled

Spinal Cord Neoplasms, Spinal Neoplasms

NCT02790294 2024-05-14

Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal

8 enrolled

Spinal Cord Neoplasms

NCT04219969 2024-05-09

FDG PET-MRI for the Diagnosis of Spinal Cord Lesions

11 enrolled

Spinal Cord Neoplasms

NCT01236560 2024-02-20

Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma

Phase 2/3 Completed

101 enrolled 15 charts

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Astrocytoma, Spinal Cord Neoplasms

NCT00788125 2023-07-14

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Phase 1/2 Terminated

7 enrolled 9 charts

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Burkitt Lymphoma, Carcinoma, Renal Cell, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Spinal Cord Neoplasms, Teratoma, Testicular Neoplasms, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Nephroma, Mesoblastic, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT05096468 2023-07-06

Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.

Phase 2/3 Completed

90 enrolled

Pain, Postoperative, Spinal Cord Neoplasms

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT05678608 2023-01-10

Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Phase NA Unknown

20 enrolled

Spinal Cord Neoplasms

NCT04578691 2022-11-10

Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery

55 enrolled

Spinal Cord Neoplasms, Spinal Injuries

NCT02085941 2022-08-15

Image-guided Cryoablation of Head, Neck and Spine Tumors

30 enrolled 10 charts

CNSHead & Neck

Head and Neck Neoplasms, Spinal Cord Neoplasms

NCT05493228 2022-08-09

Dexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients

Phase 3 Unknown

38 enrolled

Spinal Cord Neoplasms

NCT02013297 2022-03-08

SBRT

61 enrolled

CNSThoracic

Brain Neoplasms, Ependymoma, Lung Neoplasms, Spinal Cord Neoplasms

NCT05106179 2021-11-03

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Phase 4 Unknown

1,000 enrolled

Spinal Cord Neoplasms

NCT02225223 2021-08-11

STARRT

Phase NA Terminated

35 enrolled 12 charts

Pain, Spinal Cord Neoplasms

NCT04968730 2021-07-20

Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection

Phase NA Unknown

100 enrolled

Spinal Cord Neoplasms

NCT01637766 2020-08-03

SIAC

Phase 1 Completed

12 enrolled

Spinal Cord Compression, Spinal Cord Neoplasms, Spinal Diseases

NCT03893110 2020-04-30

Carbon PEEK Versus Titanium Pedicle Screws in the Treatment of Spinal Tumors

Phase NA Withdrawn

Spinal Cord Neoplasms

NCT04331431 2020-04-02

Outcomes of the Intradural Extramedullary Tumors Resection

24 enrolled

Spinal Cord Neoplasms

NCT01921595 2019-03-29

Impact of Balanced Slat Colloid HES 130/0.42 on Coagulation Profiles in Patients Undergoing Spinal Cord Tumor Surgery

Phase NA Terminated

6 enrolled

Spinal Cord Neoplasms, Thrombosis

NCT00826241 2019-03-22

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

58 enrolled 11 charts

Brain Neoplasms, Ependymoma, Spinal Cord Neoplasms

NCT03050203 2019-01-28

kit

37 enrolled 5 charts

Bone Diseases, Spinal Cord Neoplasms, Osteoarthritis, Spine

NCT02613390 2019-01-10

Safety Evaluation of Intra-Operative MRI-Based Guidance for Laser Ablation of Epidural Metastasis

11 enrolled

Phase EARLY_PHASE1 Completed

Spinal Cord Neoplasms

NCT00452868 2018-09-07

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

14 enrolled 7 charts