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NCT07379125 2026-05-22

Therapeutic RSK1 Targeting in Myelofibrosis

Phase 1 Recruiting

Classical hematologyMyeloid

Anemia, Bone Marrow Diseases, Hematologic Diseases, Myeloproliferative Disorders, Splenomegaly, Bone Marrow Neoplasms, Primary Myelofibrosis

NCT07575854 2026-05-13

SPLENIC-SIRT

Phase NA Not yet recruiting

Gastrointestinal

Gastrointestinal Neoplasms, Splenomegaly

NCT05992532 2026-02-11

GammaGA: Prevalence of Acid Sphingomyelinase Deficiency Disease (ASMD) and Gaucher Disease in Patients With Monoclonal Gammopathies and/or Multiple Myeloma

Gaucher Disease, Multiple Myeloma, Niemann-Pick Diseases, Paraproteinemias, Splenomegaly

NCT03895112 2023-02-10

MPN-RC 118 AVID200 in Myelofibrosis

Phase 1 Completed

Fibrosis, Splenomegaly, Primary Myelofibrosis

NCT02055781 2021-11-18

PAC326

Phase 3 Terminated

311 enrolled 12 charts

Classical hematologyMyeloid

Anemia, Bone Marrow Diseases, Hematologic Diseases, Hemorrhagic Disorders, Myeloproliferative Disorders, Polycythemia Vera, Splenomegaly, Thrombocythemia, Essential, Thrombocytopenia, Primary Myelofibrosis

NCT04716166 2021-10-20

Incentive Spirometry and Upper Abdominal Laparoscopic Surgery

Phase NA Completed

Gastrointestinal

Cholecystitis, Hernia, Diaphragmatic, Hernia, Hiatal, Pancreatic Neoplasms, Splenic Infarction, Splenomegaly, Choledocholithiasis

NCT02948283 2021-02-12

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

Phase 1 Completed

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

Lymphadenopathy, Anemia, Fatigue, Fever, Lymphocytosis, Multiple Myeloma, Splenomegaly, Thrombocytopenia, Weight Loss, Leukemia, Lymphocytic, Chronic, B-Cell

NCT01773187 2020-09-29

Pacritinib Versus Best Available Therapy to Treat Myelofibrosis

Phase 3 Terminated

327 enrolled 11 charts

Classical hematologyMyeloid

Anemia, Bone Marrow Diseases, Hematologic Diseases, Myeloproliferative Disorders, Polycythemia Vera, Splenomegaly, Thrombocythemia, Essential, Thrombocytopenia, Primary Myelofibrosis

NCT04524650 2020-08-28

Early Diagnosis of Oxaliplatin-induced Portal Hypertension

Gastrointestinal

Hypertension, Portal, Splenomegaly, Colorectal Neoplasms

NCT04524676 2020-08-24

Oxaliplatin-induced Portal Hypertension

Phase NA Unknown

Gastrointestinal

Hypertension, Portal, Splenomegaly, Colorectal Neoplasms

NCT02730884 2020-08-07

Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia

Phase 2 Terminated

3 enrolled 6 charts

Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Leukemia, Splenomegaly, Primary Myelofibrosis

NCT02421354 2019-05-15

Nivolumab in Treating Patients With Primary Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis, or Post-Polycythemia Vera Myelofibrosis

Phase 2 Terminated

8 enrolled 7 charts

Hepatomegaly, Polycythemia Vera, Splenomegaly, Primary Myelofibrosis

NCT01201655 2010-09-14

Study of the Impact of Hypersplenism and Splenectomy on Hepatocarcinogenesis in Patients With Posthepatitic Cirrhosis

Gastrointestinal

Carcinoma, Hepatocellular, Liver Cirrhosis, Splenomegaly