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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Lymphoid 1Classical hematology 1

Conditions

Breast Neoplasms 13Neoplasms 12Brain Neoplasms 6Prostatic Neoplasms 5Neoplasm Metastasis 4Lung Neoplasms 4Sarcoma 3Multiple Myeloma 3Melanoma 3Glioblastoma 3Gastrointestinal Neoplasms 3Esophageal Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Uterine Cervical Neoplasms 2Thymus Neoplasms 2Stomach Neoplasms 2Sarcoma, Synovial 2Rectal Neoplasms 2Pain 2Ovarian Neoplasms 2Oligodendroglioma 2Neuroendocrine Tumors 2Nasopharyngeal Carcinoma 2Mesothelioma 2Liposarcoma 2Hematologic Neoplasms 2Head and Neck Neoplasms 2Glioma 2Fatigue 2Colorectal Neoplasms 2

Interventions

Surveys and Questionnaires 211-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 2Ritonavir 1Quality of Life 1ON 01910 1Nivolumab 1Metformin 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Splenomegaly × Quality of Life × Clear all
NCT02948283 2021-02-12

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

City of Hope Medical Center

Phase 1 Completed
3 enrolled
Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

Lymphadenopathy, Anemia, Fatigue, Fever, Lymphocytosis, Multiple Myeloma, Splenomegaly, Thrombocytopenia, Weight Loss, Leukemia, Lymphocytic, Chronic, B-Cell

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